The Mechanism and Prevention Strategies of Postoperative Intestinal Adhesion and Infectious Complications in Patients with Acute Appendicitis

Authors

  • Wendong Luo Faculty of Medicine, Universiti Sultan Zainal Abidin, Terengganu, Malaysia
  • Ong Swee Leong Faculty of Medicine, Universiti Sultan Zainal Abidin, Terengganu, Malaysia
  • Haniif Ahmad Mazian KPJ Sri Manjung Specialist Hospital, Perak, Malaysia
  • Hasmali Mohamad Faculty of Medicine, Universiti Sultan Zainal Abidin, Terengganu, Malaysia
  • Harmy Mohamef Yusoff Faculty of Medicine, Universiti Sultan Zainal Abidin, Terengganu, Malaysia
  • Tiejun He The Third Affiliated Hospital of Jinzhou Medical University, China

Keywords:

Appendectomy, Postoperative Adhesions, Surgical Site Infections, Inflammatory Markers, Laparoscopic Surgery

Abstract

Following appendectomy invasive complications such as adhesions and infections persist as crucial medical problems. Examining both the frequency and influencing elements plus patient outcomes of these medical issues creates guidelines for effective management solutions. A follow-up period of one year after surgery was implemented for 125 patients who underwent appendectomy procedures between January and December 2023 within this prospective observational study. Researchers used univariate statistical methods to evaluate the incidence of adhesion formation and influential risk factors such as patient attributes and surgical techniques combined with infection rates. Adhesions formed after surgery impacted 20 patients (16.0%), resulting in adhesive bowel obstruction for 6 patients (4.8%) while another 14 patients (11.2%) had non-specific signs on imaging postoperatively. Research found patients who developed adhesions possessed considerably elevated neutrophil-to-lymphocyte ratios (NLR) while surgical procedures for these patients were more frequently carried out as open surgeries compared to patients without adhesions showing statistical significance (p < 0.05). While SSIs showed a rise from 12 at the 30-day mark to 17 cases after 12 months the numbers of intra-abdominal abscesses remained constant at 7 cases and stable at 3 cases for sepsis. Laparoscopic surgery first-line approaches together with inflammatory marker-based risk assessment and enhanced existing postoperative procedures lead to better treatment results by lowering complication rates in appendicitis cases.

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Published

2025-09-13

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