Brazilian Journal of Pathology and Laboratory Medicine

Please contact: journal@jbpml.org.br

Vol 57, Issue 1

CRISP3 glycoprotein: a good biomarker for prostate cancer?

Aparecida de Lourdes Carvalho; Sebastião A. Pinto; Wagner G. dos SantosJ. Bras. Patol. Med. Lab. 2021;57(1):1-7 ABSTRACT INTRODUCTION: Cysteine-rich secretory protein 3 (CRISP3) is expressed at low levels in normal human prostate but often overexpressed in prostate cancer (PCa). The relevance of this overexpression for the malignancy of PCa is still unclear. The prognostic value of […]

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Evaluation of urinalysis pre-analytical phase in a private laboratory of Maringá city, Paraná, Brazil

Mariana M. Saramela; Talma R. L. FernandesJ. Bras. Patol. Med. Lab. 2021;57(1):1-6 ABSTRACT INTRODUCTION: Routine urinalysis is among the most requested exams in the clinical laboratory, assisting in the diagnosis of various diseases and treatment follow-up. In this case, the pre-analytical phase is extremely important because the quality of the sample directly influences the analysis and

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Timeline analysis of IgA and IgG levels in Covid-19 hospitalized patients according to the clinical outcome

Thalia Medeiros; Fabiana R. Carvalho; Renan Faustino; Gabriel M. C. Guimarães; Lilian S. Alves; Any Caroline Oliveira; Elzinandes L. Azeredo; Jorge R. Almeida; Luzia Maria O. Pinto; Andrea Alice SilvaJ. Bras. Patol. Med. Lab. 2021;57(1): ABSTRACT INTRODUCTION: Studies suggest the association between antibody production and the severity of coronavirus disease 2019 (Covid-19). Objectives: To evaluate the

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Pie charts showing percentages of patients with CTCs detected by analyses of the expression of TWIST-1, MGA and the combination of expression of both genes CTCs: circulating tumor cells.

The combination of mammaglobin A and TWIST-1 increases detection of circulating tumor cells in breast cancer

Georgina Gallucci; Estefanía Massa; Carlos C. Funes; Roberto Tozzini; Sergio Ghersevich J. Bras. Patol. Med. Lab. 2021;57(1):1-10 ABSTRACT OBJECTIVES: Breast cancer cells that are released into the bloodstream are called circulating tumor cells (CTCs). CTCs can express different genes, like TWIST-1 and mammaglobin A (MGA). The aims of this study were to analyze the expression of TWIST-1 and MGA in the blood

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Distribuição dos valores medianos de testosterona total com os participantes da coleta realizando ou não jejum de 8 horas

Evaluation of the influence of pre-analytical factors on total testosterone levels in healthy young men

Isabela L. Lima; Isabelly M. Neves; Izabela R. Costa; Matheus C. Caplum; Pedro C. B. Oliveira; Rômulo C. Vaz de Mello J. Bras. Patol. Med. Lab. 2021;57(1):1-6 DOI: 10.5935/1676-2444.20210016 Evaluation of the influence of pre-analytical factors on total testostero ABSTRACT INTRODUCTION: Testosterone is the main hormone that regulates male reproductive functions, directly participating in spermatogenesis and

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Relationship between serum concentrations of uric acid, insulin resistance and metabolic alterations in adolescents

Malene L. G. Sodré; Alice S. Ferreira; Andressa C. Ferreira; Anne Caroline S. Silva; Carla Milena A. Sá; Carlos Alberto D. Filho; Sally Cristina M. Monteiro J. Bras. Patol. Med. Lab. 2021;57(1):1-7DOI: 10.5935/1676-2444.20210020 ABSTRACT OBJECTIVE: To verify the possible relationship between serum uric acid concentrations and insulin resistance in adolescents.METHODS: This is a cross-sectional study with 74

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Fotomicrografias de imunomarcação para TIMP-1 em CCE

Analysis of TIMP-1 expression in leukoplakia and oral squamous cell carcinoma

Susy Carmelita P. Nascimento; Letícia N. G. Souza; Liliana Aparecida P. Barros J. Bras. Patol. Med. Lab. 2021;57(1):1-11 ABSTRACT INTRODUCTION: The current study about transition of oral epithelial dysplasia, present in lesions such as leukoplakia, for squamous cell carcinoma (SCC) involves not only the histopathological aspects, but also the analysis of the presence of biomarkers which

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Follow-up of squamous atypia’s and the evaluation of the conducts according to the recommendations of the Ministry of Health

Mateus F. Delabeneta; Dayane B. Costa; Jacqueline Plewka; Maiara Aline Santos; Maurício TurkiewiczJ. Bras. Patol. Med. Lab. 2021;57(1):1-7DOI: 10.5935/1676-2444.20210028 ABSTRACT INTRODUCTION: Cervical cancer is considered a public health problem, ranking fourth among the most common types of cancer worldwide.OBJECTIVE: The present study aimed to gather information on the follow-up, and to verify adherence to the management recommended

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Impact of pre-analytical errors on costs of clinical analysis laboratory

Priscila R. Santos; Camila L. Silva; Magda C. Gall; Allyne Cristina GrandoJ. Bras. Patol. Med. Lab. 2021;57(1):1-5DOI: 10.5935/1676-2444.20210023 ABSTRACT INTRODUCTION: Currently, it is well known that quality assurance systems in healthcare organizations are constantly evolving. Quality improvements can reduce costs by avoiding repetition of exams, which results in a waste of time and money for the

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Rumack-Matthew Nomogram(11)

Use of different matrices to construct the standard curve for the paracetamol dosage by visible spectrophotometry

Caroline M. Barros; Andresa P. Silva; Juliana O. S. S. Mizael; Yoko Oshima-FrancoJ. Bras. Patol. Med. Lab. 2021;57(1):1-7 ABSTRACT INTRODUCTION: Acute paracetamol poisoning is confirmed by the determination of its serum level and allows assessing the risk of hepatotoxicity, which can be monitored by the Rumack-Matthew nomogram for the administration of the N-Acetylcysteine antidote, as well

Use of different matrices to construct the standard curve for the paracetamol dosage by visible spectrophotometry Read More »