Brazilian Journal of Pathology and Laboratory Medicine

Please contact: journal@jbpml.org.br

Vol 57, Issue 1

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

The influence of tobacco and alcohol in oral cancer: literature review

Rafaella B. Leite; Ana Carla O. Marinho; Beatriz L. Costa; Maria Beatriz V. Laranjeira; Kleyber D. T. Araújo; Anaícla F. M. CavalcantiJ. Bras. Patol. Med. Lab. 2021;57(1):1-5 ABSTRACT In Brazil, smoking and drinking are more common in male patients, less frequently affecting female patients. The most diagnosed type of lesion is squamous cell carcinoma. This […]

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Complications of idiopathic thrombocytopenic purpura in pregnancy: a review of literature

Camila L. Silva; Allyne Cristina GrandoJ. Bras. Patol. Med. Lab. 2021;57(1):1-9 ABSTRACT INTRODUCTION: Idiopathic thrombocytopenic purpura (ITP) is an acquired immune disorder that causes a reduction in platelet count, called thrombocytopenia. ITP during pregnancy usually presents some complications that may impair the outcome of pregnancy.OBJECTIVE: This literature review aimed to identify the main complications of ITP in

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Hereditary hemochromatosis associated with the development of liver cirrhosis

Taylla S. Costa; Jaqueline M. Ferreira; Marina F. Couto; Regina S. NascimentoJ. Bras. Patol. Med. Lab. 2021;57(1):1-10 ABSTRACT Hereditary hemochromatosis (HH) is an autosomal recessive disease, most often associated with mutations in the HFE gene, which result in continuous absorption of iron, causing its overload. Liver tissue is the main site of iron deposition; thus, high levels

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The importance of flow cytometry in the diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria

Lethicia R. Ehlert; Camila L. Silva; Allyne Cristina GrandoJ. Bras. Patol. Med. Lab. 2021;57(1):1-8 ABSTRACT INTRODUCTION: The paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal disease of the hematopoietic stem cells, and it is clinically characterized by chronic intravascular hemolysis, bone marrow failure and hypercoagulability leading to thrombosis. It is a rare disorder of the hematopoietic

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Flow cytometry as a diagnostic tool in childhood solid tumors

Gislaine Furlanetto; Fabiane Spagnol; Ana Paula Alegretti; Mariela G. Farias; Victor J. Soares; Liane E. Daudt; Jiseh F. Loss; Mariana B. MichalowskiJ. Bras. Patol. Med. Lab. 2021;57(1):1-9DOI: 10.5935/1676-2444.20210042 ABSTRACT Childhood solid tumors represent about 30% of all pediatric cancers. In recent years, there has been some expansion in the use of flow cytometry (FC) in

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Umbilical cord constriction as a cause of intrauterine fetal death

Victor Antônio Kuiava; Henrique M. Pasqual; Ana Luiza S. Garcia; Bianca L. Barbarioli; Fernanda M. Carlotto; Gabriel K. Costa; Laurenlisiê L. H. Brittes; Maiara Christine Macagnan; Nathália Dal Prá Zucco; Rubens RodriguezJ. Bras. Patol. Med. Lab. 2021;57(1):1-5 ABSTRACT The umbilical cord constriction (UCC) is an uncommon condition and an important etiology for stillborn fetuses. The

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HPV detection in oral mucosa samples in pediatric patients

Aline R. Gama; Marcos Antonio B. Carvalho Jr.; Isabela J. Wastowski; Stela O. Rodrigues; Maria Fernanda B. Souza; Lais S. Botacin; Melissa A. G. Avelino; Lilian Carla CarneiroJ. Bras. Patol. Med. Lab. 2021;57(1):1-5 ABSTRACT INTRODUCTION: The human papillomavirus (HPV) detection favors treatments for patients with clinical manifestations and limits future consequences for those with asymptomatic infections.OBJECTIVES: Therefore,

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Bleach-concentrated direct sputum smear microscopy procedure for diagnosis of pulmonary tuberculosis in poverty areas

José L. O. Magalhães; Ana Albertina Araújo; Leonardo O. Silva; Ilyana O. Coutinho; Juliana F. C. Lima; Nilma C. Leal; Alzira M. P. AlmeidaJ. Bras. Patol. Med. Lab. 2021;57(1):1-8 ABSTRACT INTRODUCTION: Pulmonary tuberculosis caused by Mycobacterium tuberculosis is a serious public health problem affecting millions of people worldwide. The development of easy and low-cost diagnostic methods

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Impact of urinary selective antibiogram in primary care

Margarida Pereira; Gabriela Poças; Valquíria AlvesJ. Bras. Patol. Med. Lab. 2021;57(1):1-5 ABSTRACT INTRODUCTION: Selective reporting of antibiotic susceptibility test results (selective antibiogram), is increasingly recognized as one of the key strategies of antibiotic stewardship programs. The objective of this study is to determine the impact of selective susceptibility reporting on ciprofloxacin utilization and Escherichia coli susceptibility

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Evaluation of galectin-3 levels in patients with type 2 diabetes mellitus and chronic kidney disease

Isabella D. P. Souza; Kathryna F. Rodrigues; Nathália T. Pietrani; Adriana A. Bosco; Karina B. Gomes; Michelle T. AlvesJ. Bras. Patol. Med. Lab. 2021;57(1):1-9 ABSTRACT INTRODUCTION: Type 2 diabetes mellitus (T2DM) is the most common manifestation of diabetes, accounting for about 90% of diagnosed cases. The causes of T2DM are not fully understood, but its pathogenesis

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