Brazilian Journal of Pathology and Laboratory Medicine

Please contact: journal@jbpml.org.br

Vol 56, Issue 1

Coronavirus in pediatrics: report of two cases and review of the literature

Lucas R. Mostardeiro; Ellen Cristine A. Antoniolli; Jady W. XavierJ. Bras. Patol. Med. Lab. 2020;56(1):1-4DOI: 10.5935/1676-2444.20200058 ABSTRACT COVID-19 was identified on December 31, 2019 in China, and has since been the subject of several studies. In the area of pediatrics, the infection appears to affect this population group more mildly when compared to adults. The […]

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Coronavirus in a patient with hepatitis C: case report

Lucas R. Mostardeiro; Ellen Cristine A. Antoniolli; Jady W. XavierJ. Bras. Patol. Med. Lab. 2020;56(1):1-3DOI: 10.5935/1676-2444.20200059 ABSTRACT In February 2020, the World Health Organization (WHO) named the infection with the new coronavirus, which appeared in December 2019 in China, as COVID-19, and defined it as a worldwide pandemic. There is not much evidence about the

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Evaluation of HLA-G immune checkpoint molecule in melanocytic lesions

Raylane P. Gomes; Gabriela Tayrine Caetano; Lucas Henrique F. Sampaio; Camila R. Silva; Maurício B. Costa; Maria Auxiliadora Cysneiro; Isabela Jubé WastowskiJ. Bras. Patol. Med. Lab. 2020;56(1):1-4DOI: 10.5935/1676-2444.20200016 ABSTRACT The human leukocyte antigen-G (HLA-G) is a non-classical molecule of the major histocompatibility complex. HLA-G has been associated with the process of tumorigenesis and tumor escape.

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Statistical association of rs2243250 polymorphism of IL4 gene and hemorrhagic stroke in Brazilian population

Ângelo M. Rolim; Felipe S. A. Borges; Aline R. Barros; Jonathan D. Lima; Fabiana B. A. Silva; Hélia Carla de Souza; Daniel O. Freire; Luzitano B. Ferreira; Izabel Cristina R. SilvaJ. Bras. Patol. Med. Lab. 2020;56(1):1-4DOI: 10.5935/1676-2444.20200031 ABSTRACT Interleukin-4 (IL-4) has great significance in inflammatory processes in cases of stroke, since it is able to

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Template for the laboratory’s report of 25-hydroxyvitamin D: recommendations form the Brazilian Society of Clinical Pathology/Laboratory Medicine (SBPC/ML) and the Brazilian Society of Endocrinology and Metabolism (SBEM)

Carlos Eduardo S. Ferreira; Carolina A. Moreira; Leonardo S. VasconcellosJ. Bras. Patol. Med. Lab. 2020;56(1):1-2DOI: 10.5935/1676-2444.20200052 ABSTRACT The Brazilian Society of Clinical Pathology/Laboratory Medicine (SBPC/ML) and the Brazilian Society of Endocrinology and Metabolism (SBEM) recommend a new template for laboratory reports of 25-hydroxyvitamin D: deficiency < 20 ng/ml; normal values for the general population between

Template for the laboratory’s report of 25-hydroxyvitamin D: recommendations form the Brazilian Society of Clinical Pathology/Laboratory Medicine (SBPC/ML) and the Brazilian Society of Endocrinology and Metabolism (SBEM) Read More »

Comparison of micronuclei frequency between smokers and non-smokers: a systematic review

Rodrigo B. Andrade; Nadine Alessandra CamposJ. Bras. Patol. Med. Lab. 2020;56(1):1-7DOI: 10.5935/1676-2444.20200022 ABSTRACT INTRODUCTION: Cancer results from the accumulation of several modifications in the genetic material and, therefore, it is possible to carry out its cytogenetic detection using biomarkers. Micronuclei (MN) have been addressed in the literature as biomarkers of genotoxic damage. These markers provide information

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Deglutition manifestations in patients with oropharyngeal cancer subjected to conservative therapy: systematic review

Jucimara N. Gois; Susana A. Barbosa; Felipe R. Matos; Carla H. Cesar; Luiz Renato ParanhosJ. Bras. Patol. Med. Lab. 2020;56(1):1-11DOI: 10.5935/1676-2444.20200046 ABSTRACT OBJECTIVES: To characterize scientific production and identify deglutition changes in individuals with oropharyngeal cancer subjected to conservative therapy.METHODS: The search was applied to five electronic database [Scientific Electronic Library Online (Scielo), Literatura Latino-Americana e do

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COVID-19: clinical and laboratory manifestations in novel coronavirus infection

Analucia R. Xavier; Jonadab S. Silva; João Paulo C. L. Almeida; Johnatan Felipe F. Conceição; Gilmar S. Lacerda; Salim KanaanJ. Bras. Patol. Med. Lab. 2020;56(1):1-9DOI: 10.5935/1676-2444.20200049 ABSTRACT COVID-19 is a highly contagious disease caused by the coronavirus of severe acute respiratory syndrome 2 (SARS-CoV-2). In 2020, due to the outbreak, it was considered by the

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Cerebrospinal fluid: history, collection techniques, indications, contraindications and complications

João Paulo S. Oliveira; Natalia T. Mendes; Álvaro R. Martins; Wilson Luiz SanvitoJ. Bras. Patol. Med. Lab. 2020;56(1):1-11DOI: 10.5935/1676-2444.20200054 ABSTRACT This article is based on a historical review of the medical literature with the purpose of acknowledging the historical stages and anatomical findings over the years, which led gradually to performance of the first lumbar

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Underreporting of scientific knowledge: a theme for reflection

Immunopathological mechanisms involved in SARS-CoV-2 infection

Sávio Breno P. Brito; Isaque O. Braga; Marília M. Moraes; Carolina C. Cunha; Sydney C. Leão; Iukary TakenamiJ. Bras. Patol. Med. Lab. 2020;56(1):1-10DOI: 10.5935/1676-2444.20200056 ABSTRACT INTRODUCTION: Coronavirus disease 2019 (Covid-19) has become a global health emergency. Although many scientific advances have been achieved over the last few months, the knowledge about how the etiologic agent SARS-CoV-2

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