Vol 55, Issue 6 – Brazilian Journal of Pathology and Laboratory Medicine

Conventional cytogenetics of patients with translocation t(15; 17) present, absent or unrecognized before and after 2006, and in the total study period NP: not performed.

Acute promyelocytic leukemia: evaluation of diagnostic tests from 2000 to 2018 in a public hospital

Article Type, Issue, Original Article, Vol 55, Issue 6 / cadmin

Aline C. Hey; Ana Paula Azambuja; Yara Carolina Schluga; Elenaide C. Nunes; Rodrigo Miguel Bendlin; Valderez R. JamurJ. Bras. Patol. Med. Lab. 2019;55(6):580-597DOI: 10.5935/1676-2444.20190052 ABSTRACT INTRODUCTION: Acute promyelocytic leukemia (APL) is caused by t(15;17)(q24;q21) translocation, which product is the fusion oncoprotein PML-RARα (promyelocytic leukemia-retinoic acid receptor alpha). The morphology of leukemic promyelocytes is usually characteristic, with the presence […]

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Intron 22 inversion and inhibitor response rate (high/low)

Prevalence of inversions in introns 1 and 22 of the factor VIII gene and inhibitors in patients from southern Brazil

Article Type, Issue, Original Article, Vol 55, Issue 6 / cadmin

Maria Cristina S. M. Corrêa; Euripides Ferreira; Marcelo T. A. Veiga; Eliane Bandinelli; Clévia RossetJ. Bras. Patol. Med. Lab. 2019;55(6):598-605DOI: 10.5935/1676-2444.20190053 ABSTRACT OBJECTIVES: The development of antibodies (inhibitors) against exogenous factors is the main complication in the treatment of hemophilia. Both genetic and non-genetic factors are related to inhibitor development. Among the genetic factors, the type

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In vitro closure of the wound healing assay area after 24 hours colchicine or paclitaxel treatment in the presence or absence of serum

Anticancer drug screening: standardization of in vitro wound healing assay

Article Type, Issue, Original Article, Vol 55, Issue 6 / cadmin

Vitor M. Almeida; Maximino Alencar Bezerra Jr.; Jéssica C. Nascimento; Lidia Maria F. AmorimJ. Bras. Patol. Med. Lab. 2019;55(6):606-619DOI: 10.5935/1676-2444.20190054 ABSTRACT INTRODUCTION: Gliomas are characterized by rapid proliferation and aggressive invasion into normal surrounding brain tissue. In medical laboratories, the in vitro wound healing assay stands out as a simple, easy, inexpensive and affordable method to evaluate cell

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Image model used for the development of the software database A) invasive lobular carcinoma; B) carcinoma in situ; C) fibroadenoma; D) invasive carcinoma of no special type; E) fibrocystic changes; F) normal breast.

Method of histopathological diagnosis of mammary nodules through deep learning algorithm

Article Type, Issue, Original Article, Vol 55, Issue 6 / cadmin

Victor Antônio Kuiava; Eliseu Luiz Kuiava; Rubens Rodriguez; Adriana Eli Beck; João Pedro M. Rodriguez; Eduardo O. ChielleJ. Bras. Patol. Med. Lab. 2019;55(6):620-632DOI: doi.org/10.5935/1676-2444.20190055 ABSTRACT INTRODUCTION: Artificial intelligence systems are promising health care technologies, mainly in medical subareas such as pathology, and can be used as support methods for the histological diagnosis of mammary nodules.OBJECTIVE: This study

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Medical Residency Training in Clinical Pathology/Laboratory Medicine at the Paulista School of Medicine, Federal University of São Paulo

Article Type, Issue, Original Article, Vol 55, Issue 6 / cadmin

Adagmar AndrioloJ. Bras. Patol. Med. Lab. 2019;55(6):633-638DOI: 10.5935/1676-2444.20190056 ABSTRACT Teaching and learning in medicine has its own characteristics, requiring from their actors, in addition to intellectual skills, great dedication and personal commitment. The object of study, learning and practice is a person, punctually placed in the position of a patient, that is, someone who must

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Distribution of tests performed by geographic region

Results of laboratory tests not accessed in Brazilian private laboratories

Article Type, Issue, Original Article, Vol 55, Issue 6 / cadmin

Wilson Shcolnik; Alex Galoro; Marcelo Lorencin; Rodolpho N. Donini; Diogo JeronimoJ. Bras. Patol. Med. Lab. 2019;55(6):639-656DOI: 10.5935/1676-2444.20190057 ABSTRACT BACKGROUND: Laboratory medicine is an important part of the health care system and directly contributes to preventive actions, diagnostics, treatment, and management of diseases. The level and quality of laboratory resources utilization have been frequently questioned. A dissemination

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Histopathological aspects A) hypercellularity in JOF; B) presence of multinucleated giant cells; C) psammomatoid pattern; D) osteoid deposition by mesenchymal cells and forming trabecular pattern; E) presence of hemorrhagic areas; F) pseudocystic degeneration present in case 1.

Juvenile ossifying fibroma: series of seven cases focusing on clinical and pathological aspects

Article Type, Case Report, Issue, Vol 55, Issue 6 / cadmin

Katianne S. Rodrigues; Glória Maria França; Everton F. Morais; Joaquim Felipe Jr.; Roseana A. Freitas; Hébel C. GalvãoJ. Bras. Patol. Med. Lab. 2019;55(6):657-666DOI: 10.5935/1676-2444.20190058 ABSTRACT Juvenile ossifying fibroma (JOF) is an uncommon benign fibro-osseous lesion that affects young individuals and deserves attention because it presents an aggressive clinical behavior and high rates of recurrence. This

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Bloodstream infection by acinetobacter radioresistens: the first case report in Brazil

Article Type, Case Report, Issue, Vol 55, Issue 6 / cadmin

Maria Carolina Lopes; Bruna S. Évora; Thiago André Cidral; Larissa B. Botelho; Maria Celeste N. MeloJ. Bras. Patol. Med. Lab. 2019;55(6):667-672DOI: 10.5935/1676-2444.20190059 ABSTRACT This report is the description of the first case in Brazil of community-acquired bloodstream infection caused by Acinetobacter radioresistens. A 73-year-old male patient with Alzheimer’s and Parkinson’s disease was hospitalized and diagnosed with pneumonia

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Choroid plexus papilloma: case report

Article Type, Case Report, Issue, Vol 55, Issue 6 / cadmin

Wilker D. Martins; Wander N. NavesJ. Bras. Patol. Med. Lab. 2019;55(6):673-680DOI: 10.5935/1676-2444.20190060 ABSTRACT Choroid plexus papillomas (CPP) are a rare oncological condition. They affect mostly the pediatric population, and the diagnosis is associated with clinical findings, imaging and anatomopathological methods. We report the case of a 49-year-old woman who underwent neurosurgical evaluation for chronic headache

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Glandular odontogenic cyst: report of an unusual case in the posterior mandible

Article Type, Case Report, Issue, Vol 55, Issue 6 / wadmin

Glória Maria França; Camila Tatyanne S. Freitas; Luis F. Almeida Neto; Luiz Carlos Moreira Jr.; Petrus P Gomes; Hébel C. GalvãoJ. Bras. Patol. Med. Lab. 2019;55(6):681-690DOI:10.5935/1676-2444.20190061 ABSTRACT The glandular odontogenic cyst (GOC) is an uncommon developmental cyst that presents glandular differentiation and has potential for recurrence. Clinically, it is asymptomatic and it has slow growing.

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