Vol 55, Issue 4 – Brazilian Journal of Pathology and Laboratory Medicine

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Longitudinal analysis of laboratory tests in a population-based study

Article Type, Issue, Original Article, Vol 55, Issue 4 / cadmin

Anna Cecília Roncalio; Caroline Galgowski; Mayra Alice Corrêa; Leonardo André Lange; Celina Noriko Yamanaka; Tatiani Karini Rensi; Caio Mauricio M. de CordovaJ. Bras. Patol. Med. Lab. 2019;55(4):348-359DOI: 10.5935/1676-2444.20190032 ABSTRACT Clinical laboratories must have quality management systems that guarantee the reliability of their results. Furthermore, in longitudinal studies, it is important that the generated data be […]

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Concentration of serum TG of subjects with and without hypercholesterolemia measured after 12-hour fast and during postprandial period Figure shows the serum TG concentration of male subjects without (n = 13) and with (n = 8) hypercholesterolemia (A), and of male subjects with hypercholesterolemia using (n = 5) or not (n = 3) oral drugs (B). It also shows the serum TG concentration of female volunteers without (n = 15) and with (n = 14) hypercholesterolemia (C), and female volunteers with hypercholesterolemia using (n = 8) or not (n = 6) oral medications (D). The data represent the mean ± standard error of mean. TG: triglyceride; *p < 0.05 and ***p < 0.001 when comparing fasting and postprandial values obtained from the same individual (paired samples t-test).

The influence of different types of fasting on lipid profile of volunteers from a city of Rio Grande do Sul, Brazil

Article Type, Issue, Original Article, Vol 55, Issue 4 / cadmin

Cláudia Regina Colla; Diego Carvalho; Aline P. RemorJ. Bras. Patol. Med. Lab. 2019;55(4):360-377DOI: 10.5935/1676-2444.20190033 ABSTRACT INTRODUCTION: Determination of lipid profile includes triglycerides (TG), total cholesterol and fractions as high-density lipoprotein cholesterol (HDL-c) and low-density lipoprotein cholesterol (LDL-c). These parameters are valuable in the risk assessment of developing cardiovascular disease. However, some pre-analytical factors, such as the

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Gating strategy used in the FC500 cytometer and Kaluza analysis software A) selection of the viable population by means of side scatter × forward scatter; B) side scatter × CD45 with gate in the region of total lymphocytes; C, D, E) inside the gate of lymphocytes, we identified populations of T, B, and NK lymphocytes; F, G, H) still inside the gate of lymphocytes, we identified a population of CD3 T lymphocytes and the CD4 and CD8 subpopulations.

Aquios CL flow cytometer performance in the automated quantification of lymphocyte subpopulations

Article Type, Issue, Original Article, Vol 55, Issue 4 / cadmin

Laiz C. Bento; Rodolfo P. Correia; Eduardo C. Pedro; Anderson M. Alexandre; Andressa C. Vaz; Daniela Schimidell; Rodrigo S. Barroso; Nydia S. BacalJ. Bras. Patol. Med. Lab. 2019;55(4):378-389DOI: 10.5935/1676-2444.20190034 ABSTRACT Flow cytometry (FC) is an essential tool for diagnosis, prognosis and therapeutic follow-up of several hematologic malignancies. In addition, it performs the quantification of lymphocytes

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Clinical and laboratory evolution of measles IgM and IgG: immunoglobulin class M and G. Source: Adapted from WHO, 2007.

Clinical, laboratorial diagnosis and prophylaxis of measles in Brazil

Article Type, Issue, Review Article, Vol 55, Issue 4 / cadmin

Analucia R. Xavier; Thalles S. Rodrigues; Lucas S. Santos; Gilmar S. Lacerda; Salim KanaanJ. Bras. Patol. Med. Lab. 2019;55(4):390-401DOI: 10.5935/1676-2444.20190035 ABSTRACT Measles is an acute febrile exanthematic disease of viral etiology, highly contagious, being the cause of morbidity and mortality of children in developing countries, whereas it has become rarer in developed countries due to

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Cadeia de rastreabilidade metrológica Adaptado de ISO 17511:2003(14).

Rastreabilidade em medicina laboratorial: um estímulo global para resultados exatos no cuidado com o paciente

Article Type, Issue, Review Article, Vol 55, Issue 4 / cadmin

Jane Luíza N. Fernandes; Wagner Wollinger; Bruno C. GarridoJ. Bras. Patol. Med. Lab. 2019;55(4):402-411DOI: 10.5935/1676-2444.20190036 ABSTRACT Laboratory medicine results influence a high percentage of all clinical decisions. Globalization requires that laboratory medicine results should be transferable between methods in the interests of patient safety. International collaboration is necessary to deliver this requirement. That collaboration should

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Microscopy, 400×, HE: spindle cells, with elongated nuclei and abundant cytoplasm HE: hematoxylin and eosin.

Giant gastrointestinal stromal tumor of the proximal ileum

Article Type, Case Report, Issue, Vol 55, Issue 4 / cadmin

Kelen Christina A. BezzerraJ. Bras. Patol. Med. Lab. 2019;55(4):412-415DOI: 10.5935/1676-2444.20190037 ABSTRACT The gastrointestinal stromal tumors (GIST) are rare and consist in mesenchymal neoplasms of the gastrointestinal tract, which may affect any part of the gastrointestinal tract, and is more frequent in stomach. We report a case of a 65-years-old male patient who presented a mass

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Flowchart of warm AHAI treatment AIHA: autoimmune haemolytic anemia; IVGV: intravenous immunoglobulins; Ab: antibody.

Evans syndrome in male lupus patient: case report

Article Type, Case Report, Issue, Vol 55, Issue 4 / cadmin

Barbara F. Dalmaso, Afonso José P. Cortez, Maitê Alexandra E. Velasquez, Warlindo C. Silva Neto, Flávio Aparecido R. Silva, Lívia Mara S. SousaJ. Bras. Patol. Med. Lab. 2019;55(4):416-425DOI: 10.5935/1676-2444.20190038 ABSTRACT Evans syndrome (ES) is a rare autoimmune disease of unknown etiology. ES occurs when there is a combination of autoimmune hemolytic anemia (AIHA) with thrombocytopenia,

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A) MRI in T1-weighted axial image without contrast demonstrating well-defined extra-axial mass in the posterior fossa (curved light gray arrow), projecting to the adjacent soft parts; B) MRI, T1-weighted post-contrast sagittal image demonstrating well-defined extra-axial mass in the posterior fossa traversing the posterolateral inferior occipital bone, projecting to the adjacent soft parts, with intense peripheral enhancement by contrast (fine white arrow), striking the cerebellar hemispheres (curved arrow) and distorting the fourth ventricle with severe hydrocephalus upstream (gray arrow) MRI: magnetic resonance imaging.

Aggressive osteoblastoma with degeneration to secondary aneurysmal bone cyst

Article Type, Case Report, Issue, Vol 55, Issue 4 / cadmin

Marcio Luís Duarte; José Luiz M. A. Prado; Carlos Alexandre M. Pereira; Maria Teresa S. Alves; Luiz Carlos D. ScoppettaJ. Bras. Patol. Med. Lab. 2019;55(4):426-433DOI: 10.5935/1676-2444.20190039 ABSTRACT A 4-year-old male patient presented with headaches that started 18 months ago and were associated with progressive loss of balance and difficulty walking. Magnetic resonance imaging (MRI) demonstrated

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Expression of FoxP3 in different forms of leprosy and reactions

Article Type, Brief Communication, Issue, Vol 55, Issue 4 / cadmin

Chalita Patricia Lima; Elisa M. Costa; Lucas F. SampaioJ. Bras. Patol. Med. Lab. 2019;55(4):434-441DOI: 10.5935/1676-2444.20190040 ABSTRACT Although regulatory T cells (Treg) are important in the immune regulation of various pathological processes, the role of these cells in the immunology of leprosy still needs to be better evaluated. The objective of this work is to quantify

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Cancer registries and pathologists

Article Type, Issue, Letter To Editor, Vol 55, Issue 4 / cadmin

Gil P. PenaJ. Bras. Patol. Med. Lab. 2019;55(4):442-445DOI: 10.5935/1676-2444.20190041 Dear Sir editor, The American Joint Committee on Cancer (AJCC) Cancer Staging Manual, 8th edition, was dedicated to Cancer Registrars, in recognition of their commitment, professionalism, dedication and leadership, related to the recording and maintenance of data that are vital for the care of cancer patients and

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