Brazilian Journal of Pathology and Laboratory Medicine

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Vol 54, Issue 2

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Standards for the diagnosis and treatment of chronic myeloid leukemia

Article Type, Editorial, Vol 54, Issue 2 /

Paulo CampregherJ. Bras. Patol. Med. Lab. 2018;54(2):68DOI:10.5935/1676-2444.20180023 ABSTRACT Myeloproliferative disorders are a group of clonal myeloid neoplasms characterized by increased proliferation of myeloid cells with preserved cell differentiation. The molecular features of myeloproliferative neoplasms have been efficiently mapped in the last decades(1). Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm defined by the presence of […]

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Mean values of the concentrations of samples extracted by the two methods PKM: proteinase K method.

Comparison of DNA extraction using proteinase K and extraction kit: analysis of the quality of the genetic material

Article Type, Issue, Original Article, Vol 54, Issue 2 /

André Luís F. Santos; Carolina Q. P. Oliveira; Geovana Nicole P. N. Arruda; John Kenned MartinsJ. Bras. Patol. Med. Lab. 2018;54(2):70-75DOI:10.5935/1676-2444.20180013 RESUMO INTRODUÇÃO: O ácido desoxirribonucleico (DNA) é a matéria-prima para os estudos genéticos, por isso são desenvolvidas técnicas laboratoriais para sua obtenção, com concentração e integridades adequadas.OBJETIVO: Comparar dois métodos de extração de DNA em relação

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Prevalence and antimicrobial susceptibility profile of microorganisms in a university hospital from Vitória (ES), Brazil

Article Type, Issue, Original Article, Vol 54, Issue 2 /

Carla C. M. Siqueira; Alexandre C. Guimarães; Thays F. D. Mata; Rodrigo Pratte-Santos; Norma Lucia S. Raymundo; Carolina F. Dias; Rodrigo MoraesJ. Bras. Patol. Med. Lab. 2018;54(2):76-82DOI:10.5935/1676-2444.20180014 RESUMO INTRODUÇÃO: As infecções relacionadas com a assistência à saúde (IRAS) ocorrem durante a internação como resultado de morbidade subjacente, procedimentos invasivos, patologia aguda ou tratamento médico. Elas levam

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Translocation in the BCR-ABL1 gene

The role of cytogenetics and molecular biology in the diagnosis, treatment and monitoring of patients with chronic myeloid leukemia

Article Type, Issue, Review Article, Vol 54, Issue 2 /

Luiza Emy Dorfman; Maiara A. Floriani; Tyana Mara R. D. R. Oliveira; Bibiana Cunegatto; Rafael Fabiano M. Rosa; Paulo Ricardo G. ZenJ. Bras. Patol. Med. Lab. 2018;54(2):83-91DOI:10.5935/1676-2444.20180015 RESUMO Leucemia mieloide crônica (LMC) é a desordem mieloproliferativa mais comum entre as neoplasias crônicas. A história dessa doença se alia ao desenvolvimento de técnicas de análise citogenética

The role of cytogenetics and molecular biology in the diagnosis, treatment and monitoring of patients with chronic myeloid leukemia Read More »

Lateral chest X-ray. Opacity in right lung base and in midfields and left lung base, due to air space filling lesions

Hereditary thrombophilia by factor V Leiden G1691A (heterozygous) and FII prothrombin G20210A (homozygous) mutations in a patient with ischemic cerebrovascular accident

Article Type, Case Report, Issue, Vol 54, Issue 2 /

Leonardo G. P. Ruiz; Maria Gabriela L. Oliveira; Adriana L. Z. Ruiz; Camila S. Daher; Mauricio L. NogueiraJ. Bras. Patol. Med. Lab. 2018;54(2):92-94DOI:10.5935/1676-2444.20180016 RESUMO Mutações relacionadas com o fator V de Leiden (G1691A) e a protrombina (G20210A) estão associadas a um significativo aumento do risco de tromboembolismo venoso. Por meio da realização de exames moleculares

Hereditary thrombophilia by factor V Leiden G1691A (heterozygous) and FII prothrombin G20210A (homozygous) mutations in a patient with ischemic cerebrovascular accident Read More »

hyroid (HE, 40×): intense lymphocytic infiltrate diffusely associated with adipose tissue sparse within the parenchyma

Adipose metaplasia of the thyroid associated with Hashimoto’s thyroiditis with nodular hyperplasia and oncocytic cells adenoma: case report and literature review

Article Type, Case Report, Issue, Vol 54, Issue 2 /

Andrey Biff Sarris; Matheus A. Santos; Rubens Adão da Silva; Mário R. Montemor NettoJ. Bras. Patol. Med. Lab. 2018;54(2):105-108DOI:10.5935/1676-2444.20180019 RESUMO Lesões que envolvem tecido adiposo e glândula tireoide costumam ser raros. No presente relato, a metaplasia adiposa associou-se à tireoidite de Hashimoto com hiperplasia nodular e adenoma de células oncocíticas em uma paciente de 40

Adipose metaplasia of the thyroid associated with Hashimoto’s thyroiditis with nodular hyperplasia and oncocytic cells adenoma: case report and literature review Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Autopsy findings of a child with left atrial isomerism associated with pulmonary agenesis

Article Type, Case Report, Issue, Vol 54, Issue 2 /

Camilla M. V. Pereira; Larissa V. Cruz; Marina C. Girotto; André C. Cunha; Jorge Alberto B. Telles; Bruna L. Diniz; Rosana C. M. Rosa; Paulo Ricardo G. Zen; Rafael Fabiano M. RosaJ. Bras. Patol. Med. Lab. 2018;54(2):109-110DOI:10.5935/1676-2444.20180020 RESUMO O isomerismo é um defeito de lateralidade raro. Nosso objetivo foi descrever os achados da autópsia de

Autopsy findings of a child with left atrial isomerism associated with pulmonary agenesis Read More »

Histological sections stained with HE

Chondroblastic osteosarcoma of the mandible: case report

Article Type, Case Report, Issue, Vol 54, Issue 2 /

Loara Gabriela R. Oliveira; John Lennon S. Cunha; Bruno T. Bezerra; Maria de Fátima B. Melo; Juliana B. M. Fonte; Ricardo Luiz C. Albuquerque Jr.J. Bras. Patol. Med. Lab. 2018;54(2):111-115DOI:10.5935/1676-2444.20180021 RESUMO Relatamos o caso de um paciente do sexo masculino, 32 anos de idade, que realizou tomografia cone-beam para planejamento de remoção de dente incluso.

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Prevalence of carbapenemase in Enterobacteriaceae with decreased susceptibility to carbapenems isolated in a tertiary referral hospital

Article Type, Brief Communication, Issue, Vol 54, Issue 2 /

Diana M. Viegas; Valéria M. SoaresJ. Bras. Patol. Med. Lab. 2018;54(2):95-98DOI:10.5935/1676-2444.20180017 RESUMO As infecções causadas por enterobactérias com resistência aos carbapenêmicos são um grave problema de saúde pública. Este trabalho tem como objetivo analisar os mecanismos de resistência relacionados com as enterobactérias com sensibilidade diminuída aos carbapenêmicos isoladas no Hospital Júlia Kubitschek (HJK) da Fundação

Prevalence of carbapenemase in Enterobacteriaceae with decreased susceptibility to carbapenems isolated in a tertiary referral hospital Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

D2-40/podoplanin expression in chronic villitis of the placenta

Article Type, Brief Communication, Issue, Vol 54, Issue 2 /

Erika S. Abu Egal; Juliana S. Nascimento; Fernanda Meireles; Amílcar C. Mattos; Harim T. Santos; Fernanda Viviane Mariano; Albina M. A. M. AltemaniJ. Bras. Patol. Med. Lab. 2018;54(2):116-119DOI:10.5935/1676-2444.20180022 RESUMO Podoplanina/D2-40 (PDPN/D2-40) é uma proteína multifuncional que pode ser expressa no endotélio linfático e nas células imunes. Na vilosite crônica (VC), a expressão de PDPN/D2-40 ainda

D2-40/podoplanin expression in chronic villitis of the placenta Read More »