Brazilian Journal of Pathology and Laboratory Medicine

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Vol 53 issue 6

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

An overview of Acinetobacter baumannii: deciphering this amazing pathogen

Article Type, Editorial, Issue, Vol 53 issue 6 /

Rodrigo CayôJ. Bras. Patol. Med. Lab. 2017;53(6):356-357DOI: 10.5935/1676-2444.20170056 Rodrigo Cayô Escola Paulista de Medicina/Universidade Federal de São Paulo (EPM/UNIFESP), São Paulo, Brazil The genus Acinetobacter comprises several groups of closely related species(1, 2), including the Acinetobacter calcoaceticus-baumannii complex that was initially proposed in 1991(3). At that time, it had not yet been described what would become one of the […]

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Carbapenem-resistant Acinetobacter baumannii in Brazil: susceptibility profile and diversity of oxacillinases

Article Type, Issue, Laboratory medicine, Vol 53 issue 6 /

Lisiane Rocha; Mariana Pagano; Juliana C. Campos; Jorge Luiz M. Sampaio; Andreza F. Martins; Afonso Luis BarthJ. Bras. Patol. Med. Lab. 2017;53(6):358-361DOI: 10.5935/1676-2444.20170057 ABSTRACT INTRODUCTION: The Acinetobacter calcoaceticus-baumannii (ABC) complex includes five species, and the A. baumannii is the most important of them because it carries mechanisms of carbapenems resistance, especially the oxacillinases.OBJECTIVES: The objectives of this study were to identify

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Frequencies of CD39, IVS1-1, IVS1-6 and IVS1-110 mutations in beta-thalassemia carriers and their influence on hematimetric indices

Article Type, Issue, Laboratory medicine, Vol 53 issue 6 /

Willian R. Gomes; Raquel A. Santos; Juçara G. Cominal; Cristiane F. F. TavaresJ. Bras. Patol. Med. Lab. 2017;53(6):362-367DOI: 10.5935/1676-2444.20170058 ABSTRACT INTRODUCTION: Beta-thalassemia is caused by a deficient synthesis of the ß-chain of hemoglobin, which leads to a chronic, microcytic and hypochromic anemia. More than 200 mutations have already been associated with this type of thalassemia, and

Frequencies of CD39, IVS1-1, IVS1-6 and IVS1-110 mutations in beta-thalassemia carriers and their influence on hematimetric indices Read More »

Implementation of the ANA HEp-2 consensus guidelines in Brazilian clinical laboratories

Article Type, Issue, Laboratory medicine, Vol 53 issue 6 /

Glaucielen G. Silva; Clayson M. Gomes; Alessandra Dellavance; Paulo Luiz C. Francescantonio; Luís Eduardo C. Andrade; Wilson M. CruvinelJ. Bras. Patol. Med. Lab. 2017;53(6):368-376DOI: 10.5935/1676-2444.20170059 ABSTRACT INTRODUCTION: The detection of autoantibodies in HEp-2 cells represents a relevant tool for the diagnosis of autoimmune diseases, especially rheumatic autoimmune diseases. As a result of the methodological advances, the

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Consensus – reference ranges of vitamin D [25(OH)D] from the Brazilian medical societies. Brazilian Society of Clinical Pathology/Laboratory Medicine (SBPC/ML) and Brazilian Society of Endocrinology and Metabolism (SBEM)

Article Type, Issue, Laboratory medicine, Vol 53 issue 6 /

Carlos Eduardo S. Ferreira; Sergio S. Maeda; Marcelo C. Batista; Marise Lazaretti-Castro; Leonardo S. Vasconcellos; Miguel Madeira; Lilian M. Soares; Victória Z. C. Borba; Carolina A. MoreiraJ. Bras. Patol. Med. Lab. 2017;53(6):377-381DOI: 10.5935/1676-2444.20170060 ABSTRACT INTRODUCTION: Vitamin D is considered a pre-hormone and plays a crucial role in calcium homeostasis and, consequently, in bone health. The best

Consensus – reference ranges of vitamin D [25(OH)D] from the Brazilian medical societies. Brazilian Society of Clinical Pathology/Laboratory Medicine (SBPC/ML) and Brazilian Society of Endocrinology and Metabolism (SBEM) Read More »

Pseudothrombocytopenia: incidence and strategy for resolution in clinical laboratory

Article Type, Issue, Laboratory medicine, Vol 53 issue 6 /

Romário F. Prates; Robson C. Viana; Márcio V. Oliveira; Claudio L. SouzaJ. Bras. Patol. Med. Lab. 2017;53(6):382-387DOI: 10.5935/1676-2444.20170061 ABSTRACT INTRODUCTION: Pseudothrombocytopenia is an important source of pre-analytical problems in clinical laboratory; therefore it must be correctly evaluated. Low spurious platelet counts can lead to misdiagnosis.OBJECTIVE: This study aims to study the resolution of pseudothrombocytopenia in the laboratory

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Laboratory diagnosis of chronic kidney disease in adults: an overview of hospitals inserted in the Portuguese National Health System

Article Type, Issue, Vol 53 issue 6 /

Natália R. Costa; Ana R. M. Carvalho; Carla M. A. Pinto; Adagmar Andriolo; Isabel C. GuerraJ. Bras. Patol. Med. Lab. 2017;53(6):388-396DOI: 10.5935/1676-2444.20170062 ABSTRACT INTRODUCTION: The laboratory diagnosis of chronic kidney disease (CKD) is a simple and cost-effective procedure that allows the detection of early stages of the disease, which is essential to avoid kidney damage and

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Spontaneous chromatid break as clonal evolution in myelodysplastic syndrome patients

Article Type, Issue, Laboratory Medicine, Vol 53 issue 6 /

Daniela P. Borges; Ivo Gabriel F. França; Roberta Taiane G. Oliveira; Mayara M. L. Melo; Ronald F. PinheiroJ. Bras. Patol. Med. Lab. 2017;53(6):397-399DOI; 10.5935/1676-2444.20170063 ABSTRACT Myelodysplastic syndrome (MDS) is a clonal hematopoietic stem cell disorder characterized by peripheral cytopenias due to ineffective erythropoiesis and an increased risk for evolving into acute myeloid leukemia (AML). Chromosomal

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Analysis of 18 bp Ins/Del at -2549 polymorphism of the vascular endothelial growth factor gene in patients with systemic lupus erythematosus

Article Type, Issue, Laboratory Medicine, Vol 53 issue 6 /

Évelin M. Cassemiro; Daiani Cristina C. Alves; Daniel O. Freire; Lusitano B. Ferreira; Carlos Eduardo C. Lins; Izabel Cristina R. Silva; Rodrigo HaddadJ. Bras. Patol. Med. Lab. 2017;53(6):400-402DOI: 10.5935/1676-2444.20170064 ABSTRACT Systemic lupus erythematosus (SLE) is considered an autoimmune disease characterized by the action of autoantibodies, which cause chronic inflammation in various tissues of the body.

Analysis of 18 bp Ins/Del at -2549 polymorphism of the vascular endothelial growth factor gene in patients with systemic lupus erythematosus Read More »

Conservative therapy for central giant cell lesion: case report

Article Type, Issue, Pathology, Vol 53 issue 6 /

Israel L. Cavalcante; Caio César S. Barros; Rafael L. V. Osterne; Roberta B. Cavalcante; Renato Luiz M. Nogueira; Renata C. T. MedeirosJ. Bras. Patol. Med. Lab. 2017;53(6):403-406DOI: 10.5935/1676-2444.20170065 ABSTRACT Case report of central giant cell lesion (CGCL) in a 32-year-old female patient, who exhibited asymptomatic increase in mandible volume and integrity of the adjacent alveolar

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