The role of IDH1/2 mutations in the pathogenesis of secondary glioblastomas
Eduardo CambruzziJ. Bras. Patol. Med. Lab. 2017;53(5):338-344DOI: 10.5935/1676-2444.20170055 ABSTRACT Diffuse astrocytoma and glioblastoma (GBM) constitute a group of diffusely infiltrating astrocytic neoplasms, which more commonly arise in cerebral hemispheres of adults. The prevalence of malignant transformation of diffuse astrocytoma to anaplastic astrocytoma and GBM varies from 40% to 75% of cases in different series. Distinct […]
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