Vol 53 issue 3 – Brazilian Journal of Pathology and Laboratory Medicine

Underreporting of scientific knowledge: a theme for reflection

Muscle biopsy with different levels of histological sections: an old procedure as a “still modern” approach

Article Type, Issue, Vol 53 issue 3 / wadmin

Acary S. B. OliveiraJ. Bras. Patol. Med. Lab. 2017;53(3):148-149DOI: 10.5935/1676-2444.20170026 The history of muscle biopsy dates back to 1860, when Duchenne first performed a biopsy on a patient with symptoms of myopathy(1). Since then, the basic and clinical science of muscle and muscle disease has gone through three stages of development: the classical period, the […]

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Evaluation of pleural and ascitic fluid analysis on the Sysmex XE-5000 hematology analyzer

Article Type, Issue, Original Article, Vol 53 issue 3 / wadmin

Regielly Caroline R. Cognialli; Samuel Ricardo Comar; Angela Maria de Souza; Gisele Maria B. SingerJ. Bras. Patol. Med. Lab. 2017;53(3):150-158DOI: 10.5935/1676-2444.20170023 ABSTRACT INTRODUCTION: Body fluid (BF) analysis is critical to the diagnosis and monitoring of several pathological conditions. The limitations of manual cell counts have led to greater interest in the development of automated BF analysis.OBJECTIVE: To

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Study of correlation between imatinib mesylate plasma levels and hematological profile of patients undergoing treatment for chronic myeloid leukemia

Article Type, Issue, Original Article, Vol 53 issue 3 / wadmin

Emanuelle S. Dal Ponte; Sandrine C. Wagner; Rafael Linden; Helena SchirmerJ. Bras. Patol. Med. Lab. 2017;53(3):159-164DOI: 10.5935/1676-2444.20170027 ABSTRACT INTRODUCTION: Chronic myeloid leukemia (CML) is a genetic disorder of hematopoietic stem cells, resulting in a myeloproliferative expansion of blood cells. CML is associated with the presence of the Philadelphia chromosome (Ph), generating an oncogene (BCR-ABL). The current

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Description of the quality indicators defined in the National Reference Laboratory in Tuberculosis of CRPHF/Ensp/Fiocruz by means of the process mapping methodology

Article Type, Issue, Original Article, Vol 53 issue 3 / wadmin

Aila Maronna; Renata A. Souza; Fatima Cristina O. F. MontesJ. Bras. Patol. Med. Lab. 2017;53(3):165-176DOI: 10.5935/1676-2444.20170028 ABSTRACT INTRODUCTION: The National Reference Laboratory (LRN) in Tuberculosis (TB) is a laboratory unit of highly specialized technical excellence that has developed projects involving training in human resources and the enhancement of techniques essential for the diagnosis of TB. Its

Description of the quality indicators defined in the National Reference Laboratory in Tuberculosis of CRPHF/Ensp/Fiocruz by means of the process mapping methodology Read More »

Antimicrobial susceptibility of Streptococcus pneumoniae isolated from patients in the northeastern macroregion of São Paulo state, Brazil, 1998-2013

Article Type, Issue, Original Article, Vol 53 issue 3 / wadmin

Marta Inês C. Medeiros; Samanta Cristine G. Almeida; Sérgio Bokermann; Evandro Watanabe; Maria Luiza L. S. Guerra; Denise de AndradeJ. Bras. Patol. Med. Lab. 2017;53(3):177-182DOI: 10.5935/1676-2444.20170029 ABSTRACT INTRODUCTION: There are reports worldwide about the increase in infections caused by Streptococcus pneumoniae resistant to antimicrobials.OBJECTIVE: Evaluate the susceptibility profile of serotypes of Streptococcus pneumoniae associating them with pneumococcal invasive diseases (PID), as

Antimicrobial susceptibility of Streptococcus pneumoniae isolated from patients in the northeastern macroregion of São Paulo state, Brazil, 1998-2013 Read More »

No association between glutathione S-transferase M1 and T1 gene polymorphisms and susceptibility to endometriosis

Article Type, Issue, Original Article, Vol 53 issue 3 / wadmin

Letícia C. Batista; Mariangela T. Ruiz-Cintra; Marco Fábio P. Lima; Alessandra Bernadete Trovó de MarquiJ. Bras. Patol. Med. Lab. 2017;53(3):183-187DOI: 10.5935/1676-2444.20170024 ABSTRACT INTRODUCTION: Endometriosis is a common gynecologic disorder influenced by genetic and environmental factors. The glutathione S-transferase family is associated with endometriosis because its main function is cellular detoxification, so the absence of those enzymes

No association between glutathione S-transferase M1 and T1 gene polymorphisms and susceptibility to endometriosis Read More »

Study on the stability of HIV and syphilis reference materials under varied temperature conditions during their transportation

Article Type, Issue, Original Article, Vol 53 issue 3 / wadmin

Márcia J. Castejon; Rosemeire Yamashiro; Camila C. Oliveira; Elaine L. Oliveira; Edilene P. R. Silveira; Carmem Aparecida F. OliveiraJ. Bras. Patol. Med. Lab. 2017;53(3):188-195DOI: 10.5935/1676-2444.20170025 ABSTRACT INTRODUCTION: The objective of this study was to evaluate the short-term stability of the serum samples used as internal quality control (IQC) of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (Aids)

Study on the stability of HIV and syphilis reference materials under varied temperature conditions during their transportation Read More »

Muscle biopsies in dermatomyositis and polymyositis: practical relevance of analyzing different levels of histological sections of the same muscular compartment

Article Type, Issue, Original Article, Vol 53 issue 3 / wadmin

Monica T. M. Diaz; Priscila S. Fraga; Marilda G. Silva; Samuel K. ShinjoJ. Bras. Patol. Med. Lab. 2017;53(3):196-201DOI: 10.5935/1676-2444.20170031 ABSTRACT INTRODUCTION: It is frequent in medical practice to have findings with normal aspects in histological muscle biopsies from patients with dermatomyositis (DM) or polymyositis (PM). This happens because, for example, the inflammatory infiltrate occurs in foci.OBJECTIVES: To

Muscle biopsies in dermatomyositis and polymyositis: practical relevance of analyzing different levels of histological sections of the same muscular compartment Read More »

Blended learning strategies in teaching general pathology at a medical course

Article Type, Issue, Original Article, Vol 53 issue 3 / wadmin

Juliana A. Fermozelli; Mario Luis R. Cesaretti; Maria Lourdes P. BarboJ. Bras. Patol. Med. Lab. 2017;53(3):202-209DOI: 10.5935/1676-2444.20170032 ABSTRACT INTRODUCTION: In many medical schools, it is evident that learning of general pathology is deficient, mainly due to the disinterest in knowledge not directly related to professional practice and the lack of pedagogical resources that motivate learning. Blended

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Creation of a comprehensive proficiency testing program for molecular diagnosis in Brazil

Article Type, Issue, Letter To Editor, Vol 53 issue 3 / wadmin

Gustavo B. Barra; Rafael H. Jácomo; Jéssica S. Gomes; Rafael M. LopesJ. Bras. Patol. Med. Lab. 2017;53(3):194-195DOI: 10.5935/1676-2444.20170030 External quality assessment (EQA) consists in the comparison of results from a laboratory with those from an external source – a group of laboratories or a reference laboratory. The implementation of a program of this nature helps

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