Brazilian Journal of Pathology and Laboratory Medicine

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Vol 52, Issue 6

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Diet and cancer

Article Type, Editorial, Issue, Vol 52, Issue 6 /

Adagmar AndrioloJ. Bras. Patol. Med. Lab. 2016;52(6):366DOI: 10.5935/1676-2444.20160059 Cancer is a complex group of diseases with numerous possible causes. These include genetic factors, eating habits, lifestyle, viral infections, exposure to different types of potentially mutagenic agents and radiation, among others. Although it represents an important group, cancers arising from inherited gene mutations correspond to a […]

Diet and cancer Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Sepsis-associated organ dysfunction and increased supportive care are associated with high serum interleukin-6 levels

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 6 /

Adriana Carta; Maria Gabriela de Lucca; Milton D. Pires; Suzana Margareth LoboJ. Bras. Patol. Med. Lab. 2016;52(6):367-373DOI: 10.5935/1676-2444.20160060 ABSTRACT INTRODUCTION: Detection of sepsis and septic shock is essential, since any delay in initiating a proper treatment is associated with a worse prognosis.OBJECTIVE: To evaluate levels of interleukin-6 (IL-6) early in the onset of the evolution of sepsis

Sepsis-associated organ dysfunction and increased supportive care are associated with high serum interleukin-6 levels Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Analysis of laboratory tests results of patients submitted to a clinical screening program

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 6 /

Raphaela M. Zapelini; Kaiser S. Koch; Geraldo César C. Althoff; Camila S. Duarte; Eloysa M. João; Sérgio Silveira Jr.J. Bras. Patol. Med. Lab. 2016;52(6):374-381DOI: 10.5935/1676-2444.20160061 ABSTRACT INTRODUCTION: There are not studies demonstrating the major changes in biochemical tests performed in screening programs.OBJECTIVE: Identify the results found in laboratory tests of patients submitted to medical check-up program, showing

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Presence of the of anti-factor VIII inhibitor antibody

Incidence of factor VIII inhibitory antibodies in patients with hemophilia A seen at HEMOCE, Ceará, Brazil

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 6 /

Rosineide A. Carvalho; Paulo Henrique da Silva; Railson HennebergJ. Bras. Patol. Med. Lab. 2016;52(6):382-386DOI: 10.5935/1676-2444.20160056 ABSTRACT INTRODUCTION: Hemophilia A is an inherited disease caused by a deficiency of factor VIII, which results from a genetic inheritance located on the X chromosome. During treatment of patients with this disorder, factor VIII inhibitors may be present, which are

Incidence of factor VIII inhibitory antibodies in patients with hemophilia A seen at HEMOCE, Ceará, Brazil Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Clinical correlation between the Point-of-care testing method and the traditional clinical laboratory diagnosis in the measure of the lipid profile in patients seen in medical offices

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 6 /

Hermes T. Xavier; Rogerio M. Ruiz; Luiz Kencis Jr.; Giovanni Melone; William Costa; Raffael Francisco Fraga; Luciano Wajman; Marcio Krakauer; Marileia ScarteziniJ. Bras. Patol. Med. Lab. 2016;52(6):387-390DOI: 10.5935/1676-2444.20160057 ABSTRACT INTRODUCTION: Elevated plasma levels of lipids are considered the main modifiable risk factor for the cardiovascular disease. The Point-of-care testing (POCT) method provides quick results and allows

Clinical correlation between the Point-of-care testing method and the traditional clinical laboratory diagnosis in the measure of the lipid profile in patients seen in medical offices Read More »

Fetal ultrasound performed at 16 weeks of gestation showing the cystic hygroma

Use of the fluid obtained by puncture of cystic hygroma: an alternative method for fetal karyotyping

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 6 /

Maiara A. Floriani; Luiza E. Dorfman; Dayane B. Koshiyama; Tatiana D. Zen; Jorge Alberto B. Telles; André C. Cunha; Paulo Ricardo G. Zen; Rafael Fabiano M. RosaJ. Bras. Patol. Med. Lab. 2016;52(6):391-392DOI: 10.5935/1676-2444.20160062 ABSTRACT The aim of our study aim was to report the case of a fetus with Turner syndrome (TS) diagnosed by karyotype

Use of the fluid obtained by puncture of cystic hygroma: an alternative method for fetal karyotyping Read More »

Analysis of necrotic areas

Daily intake of watercress causes inhibition of experimental Ehrlich tumor growth

Article Type, Issue, Pathology, Vol 52, Issue 6 /

Débora Aparecida de Souza; Poliane M. Costa; Rosy Iara M. A. Ribeiro; Paula V. T. Vidigal; Flávia C. H. PintoJ. Bras. Patol. Med. Lab. 2016;52(6):393-399DOI: 10.5935/1676-2444.20160063 ABSTRACT INTRODUCTION: Increasing cruciferous vegetable intake has been associated with reduced risk of cancer. Experimental and epidemiological studies suggest that the watercress it is a cruciferous vegetable with high concentration

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Photomicrography, stained with HE, of the skeletal musculature of BALB/c mice after implantation of Linnea Safe

Polymethyl methacrylate (Linnea Safe) causes local inflammatory response after intramuscular implant in BALB/c mice but it is not observed in distant organs

Article Type, Issue, Pathology, Vol 52, Issue 6 /

Eduardo Luiz Costa; Anália C. Milhomem; Ronaldo Moisés de Moura Filho; Ruy S. Lino Jr.J. Bras. Patol. Med. Lab. 2016;52(6):400-406DOI: 10.5935/1676-2444.20160058 ABSTRACT INTRODUCTION: Among its different therapeutic functions, the use of polymethyl methacrylate (PMMA) for more than a decade has has stood out in the replacement of the volumes lost with the aging process and filling

Polymethyl methacrylate (Linnea Safe) causes local inflammatory response after intramuscular implant in BALB/c mice but it is not observed in distant organs Read More »

Immunohistochemical reaction

Immunohistochemical analysis of apoptosis and cell proliferation in lungs of premature infants with chronic lung disease (bronchopulmonary dysplasia)

Article Type, Issue, Pathology, Vol 52, Issue 6 /

Sandra Mara Witkowski; Lúcia de Noronha; Cristina T. Okamoto; Carlos F. Oldenburg Neto; Tammy Almeida; Seigo Nagashima; João A. BahrJ. Bras. Patol. Med. Lab. 2016;52(6):407-415DOI: 10.5935/1676-2444.20160064 ABSTRACT INTRODUCTION: The pathophisiology of chronic lung disease (CLD), clinically known as bronchopulmonary dysplasia is not clear. It is believed that protective mechanisms, such as the release of inflammatory mediators

Immunohistochemical analysis of apoptosis and cell proliferation in lungs of premature infants with chronic lung disease (bronchopulmonary dysplasia) Read More »

ISH Sample number 30 (lymph node) labeled by the five probes A-E. A-E) positive cells are labeled in brown or purple (bold arrows); F) RNA negative probe. Original magnification 400× from A to F. ISH: in situ hybridization; RNA: ribonucleic acid.

Comparative study of five commercial probes for the detection of Epstein-Barr virus (EBV) by in situ hybridization in cases of nodular sclerosis Hodgki’s lymphoma

Article Type, Issue, Pathology, Vol 52, Issue 6 /

Suely Nonogaki; Neuza K. Shirata; Lidia M. Kimura; Juliana M. Guerra; Raphael S. S. Medeiros; Roberto Antonio P. Paes; Cristina T. Kanamura; Camila C. Oliveira; Yara de MenezesJ. Bras. Patol. Med. Lab. 2016;52(6):416-425DOI: 10.5935/1676-2444.20160065 ABSTRACT INTRODUCTION: Epstein-Barr virus (EBV) may serve as a target in therapeutic treatments, thus reliable diagnostic results are necessary.OBJECTIVE: The aim of this

Comparative study of five commercial probes for the detection of Epstein-Barr virus (EBV) by in situ hybridization in cases of nodular sclerosis Hodgki’s lymphoma Read More »