Vol 52, Issue 4 – Brazilian Journal of Pathology and Laboratory Medicine

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Review of the Brazilian Guidelines for Cervical Cancer Screening, 2016

Article Type, Editorial, Issue, Vol 52, Issue 4 / cadmin

Leticia Maria C. KatzJ. Bras. Patol. Med. Lab. 2016;52(4):210DOI: 10.5935/1676-2444.20160034 It is about to be published the second edition of the Brazilian Guidelines for Cervical Cancer Screening, as part of another publication of the Brazilian National Cancer Institute (Instituto Nacional de Câncer [Inca]). For the development of the document participated the members of the Collaborative […]

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Genotype distribution of GSTP1 polymorphism in relation to gender. Chi-square test p = 0.8674 GSTP1: glutathione S-transferase P1.

Association between the glutathione S-transferase P1 (GSTP1) Ile105Val gene polymorphism in obese and overweight patients over 60 years

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 4 / cadmin

Eduardo O. Chielle; Paola C. Fortuna; Jorlana S. MazieroJ. Bras. Patol. Med. Lab. 2016;52(4):211-216DOI: 10.5935/1676-2444.20160035 ABSTRACT INTRODUCTION: Obesity is related to the possibility of a number of metabolic damage associated with oxidative stress. The enzymes of the glutathione S-transferase (GST) family have the function of promoting detoxification; however, polymorphisms in the glutathione S-transferase P1 (GSTP1) gene

Association between the glutathione S-transferase P1 (GSTP1) Ile105Val gene polymorphism in obese and overweight patients over 60 years Read More »

Band pattern of positive and negative samples for HLA-B*27 by PCR-SSP in agarose gel with standardized mix PCR-SSP: polymerase chain reaction-single specific primer; HLA: human leukocyte antigens; H: HLA-B*27 positive; C: HLA-B*27 negative; BNK: blank. Step ladder: 50 pb.

Application of PCR-SSP method for HLA-B*27 identification as an auxiliary tool for diagnosis of ankylosing spondylitis

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 4 / cadmin

Gisele Cristina A. Oliveira; Eliane P. Ambrosio-Albuquerque; Jeane Eliete L. VisentainerJ. Bras. Patol. Med. Lab. 2016;52(4):217-222DOI: 10.5935/1676-2444.20160036 ABSTRACT INTRODUCTION: Human leukocyte antigens (HLA) are molecules that present antigen to the immune system; their presence or absence have been described as an influential factor in some diseases. HLA-B*27 is an HLA polymorphism that has been associated with increased susceptibility

Application of PCR-SSP method for HLA-B*27 identification as an auxiliary tool for diagnosis of ankylosing spondylitis Read More »

Is the creatine kinase isoenzyme MB level a marker of myocardial ischemia in ventilated premature infants?

Article Type, Issue, Pathology, Vol 52, Issue 4 / cadmin

Gisele Cristina A. Oliveira; Eliane P. Ambrosio-Albuquerque; Jeane Eliete L. VisentainerJ. Bras. Patol. Med. Lab. 2016;52(4):217-222Adauto D. M. Barbosa; Maria Paula S. Goldani; Israel Figueiredo Jr; Salim KanaanJ. Bras. Patol. Med. Lab. 2016;52(4):223-226DOI: 10.5935/1676-2444.20160037 ABSTRACT INTRODUCTION: It is not clear whether the levels of troponin I (TI) and creatine kinase isoenzyme MB (CK-MB) are changed in

Is the creatine kinase isoenzyme MB level a marker of myocardial ischemia in ventilated premature infants? Read More »

Prevalence of factor V Leiden in patients with venous thrombosis

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 4 / cadmin

Cristiane Aparecida Michel; Julia B. Rocha; Daiane C. Costa; Carlos Augusto Lima; Anna Paula B. BatschauerJ. Bras. Patol. Med. Lab. 2016;52(4):227-232DOI: 10.5935/1676-2444.20160038 ABSTRACT INTRODUCTION: Venous thrombosis is a multifactor disease with high incidence in the population. The development of this disease is closely linked to the presence of environmental and genetic factors and may occur in

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Species distribution and antifungal susceptibility to vulvovaginal Candida spp. in southern Mato Grosso State, Brazil

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 4 / cadmin

Letícia S. Goulart; Elicléia F. Santiago; Júlia L. Ramon; Selma V. Moura; Amanda R. Silva; Iberê F. Silva Jr; Juliana Helena Chávez-Pavoni; Claudinéia AraújoJ. Bras. Patol. Med. Lab. 2016;52(4):233-237DOI: 10.5935/1676-2444.20160039 ABSTRACT INTRODUCTION: Vulvovaginal candidiasis is a prevalent opportunistic mucosal infection, caused predominantly by Candida albicans. Candida species vary in their susceptibility to the antifungal agents, thus, the susceptibility

Species distribution and antifungal susceptibility to vulvovaginal Candida spp. in southern Mato Grosso State, Brazil Read More »

Cervical cancer screening: from Pap smear to future strategies

Article Type, Cytopathology, Issue, Vol 52, Issue 4 / cadmin

Cristina Aparecida T. S. MitteldorfJ. Bras. Patol. Med. Lab. 2016;52(4):238-245DOI: 10.5935/1676-2444.20160040 ABSTRACT Previously, the screening for detection of cervical cancer was performed by simple cervicovaginal sample collected by the physician whenever the patient attended the medical consultation, and soon it was established as the annual “Pap smear”. Since then, an elementary test has evolved into

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Histological panoramic view of prostate tissue

Features of the female prostate according to age: an autopsy study

Article Type, Issue, Pathology, Vol 52, Issue 4 / cadmin

Thalita Cristina M. Costa; Patrícia M. Cury; Ana Maria G. CustódioJ. Bras. Patol. Med. Lab. 2016;52(4):246-252DOI: 0.5935/1676-2444.20160041 ABSTRACT INTRODUCTION: The prostate gland plays an important role in male and female reproductive system. Data on this organ have not been fully explored in women since its first description, probably because it is considered a vestigial gland.OBJECTIVE: To correlate

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Quantitative analysis of inflammatory and adhesion molecules in lungs of neonates with chronic lung disease (bronchopulmonary dysplasia) receiving mechanical ventilation

Article Type, Issue, Pathology, Vol 52, Issue 4 / cadmin

Cristina T. Okamoto; Carlos F. Oldenburg Neto; Sandra Mara Witkowski; Ana Paula Percicote; Luca R. Pasqualotto; Gabriela Troiano; Tammy Almeida; Cleber M. Souza; Lúcia de NoronhaJ. Bras. Patol. Med. Lab. 2016;52(4):253-261DOI: 10.5935/1676-2444.20160042 ABSTRACT INTRODUCTION: Chronic lung disease (CLD), clinically known as bronchopulmonary dysplasia (BPD), is a major cause of morbidity in premature newborn and were submitted

Quantitative analysis of inflammatory and adhesion molecules in lungs of neonates with chronic lung disease (bronchopulmonary dysplasia) receiving mechanical ventilation Read More »

Morphological and immunohistochemical characteristics of the resected specimens A) urothelial papillary neoplasia, HE 20×; B) invasive urothelial carcinoma with discohesive growth pattern, HE 200×; C) tumor cells showed eosinophilic cytoplasm and visible nucleoli, often with intracytoplasmic vacuoles and peripheral nucleus, HE 400×; D) negative for E-cadherin staining, 200×. HE: hematoxylin and eosin.

Invasive bladder urothelial carcinoma, plasmacytoid variant: case report

Article Type, Issue, Pathology, Vol 52, Issue 4 / cadmin

Rui Pedro C. M. Oliveira; Carlos Filipe C. Abrantes; Edgar Miguel C. T. Silva; Carol A. Marinho; Vítor Manuel L. Sousa; Lígia R. C. O. A. P. CastroJ. Bras. Patol. Med. Lab. 2016;52(4):262-265DOI: 10.5935/1676-2444.20160043 ABSTRACT Invasive bladder urothelial carcinoma, plasmacytoid variant is a rare entity with scarce cases reported in the literature. We report a

Invasive bladder urothelial carcinoma, plasmacytoid variant: case report Read More »