Vol 52, Issue 2 – Brazilian Journal of Pathology and Laboratory Medicine

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

The importance of determining reference intervals for laboratory medicine

Article Type, Editorial, Issue, Vol 52, Issue 2 / cadmin

Natasha Slhessarenko; Adagmar AndrioloJ. Bras. Patol. Med. Lab. 2016;52(2):68-69DOI: 10.5935/1676-2444.20160019 Exactly 20 years ago, Forsman has shown that at least 70% of clinical decisions made within hospital setting were very dependent on the results of laboratory tests(1). Nowadays, with the remarkable technological evolution, probably this contributory percentage is even higher. The performance of a laboratory […]

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Amino acid reference intervals by high performance liquid chromatography in plasma sample of Brazilian children

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 2 / cadmin

Ana F. Cruz; Tatiana Maria C. C. Barbosa; Talita Émile R. Adelino; William P. Lima; Magda O. Mendes; Eugênia R. ValadaresJ. Bras. Patol. Med. Lab. 2016;52(2):70-77DOI: 10.5935/1676-2444.20160012 ABSTRACT INTRODUCTION: The high performance liquid chromatography is a technique used for quantification of amino acids in plasma. The definition of reference intervals in the population is very important

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Distribution of resampling percentage orders per semester

Analysis of the pre-analytical phase in a private pathology laboratory of Maringá city-PR, Brazil

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 2 / cadmin

Cristiane F. Oliveira; Talma R. L. FernandesJ. Bras. Patol. Med. Lab. 2016;52(2):78-83DOI: 10.5935/1676-2444.20160016 ABSTRACT INTRODUCTION: The pre-analytical phase involves most of the errors of clinical analysis laboratories. Information characterizing the occurrence of these errors can be useful to provide prevention and reduction strategies.OBJECTIVE: The aim of this study was to identify the main errors in the pre-analytical

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Chronic spontaneous urticaria: cutaneous reaction and laboratory aspects

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 2 / cadmin

Vitor Celso M. Campos; Letícia Yassumoto; Odilon M. Almeida Filho; Roseli N. S. Antunes; Zamir CalamitaJ. Bras. Patol. Med. Lab. 2016;52(2):84-90DOI: 10.5935/1676-2444.20160020 ABSTRACT INTRODUCTION: The chronic spontaneous urticaria (CSU) is a cutaneous reaction characterized by the formation of episodic and recurrent erythematous papules, usually pruritic, which etiology may be associated with an autoimmune response resulting from

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Percentage of 75 Acinetobacter baumannii isolates from hospital 1 according to the source of specimens

Emergence of polymyxin B-resistant Acinetobacter baumannii in hospitals in Rio de Janeiro

Issue, Laboratory Medicine, Vol 52, Issue 2 / cadmin

Gabrielle L. Genteluci; Daniela B. C. Gomes; Maria José de Souza; Karyne R. Carvalho; Maria Helena S. Villas-BôasJ. Bras. Patol. Med. Lab. 2016;52(2):91-95DOI: 10.5935/1676-2444.20160021 ABSTRACT INTRODUCTION: Acinetobacter baumannii has been considered a prevalent pathogen in hospitals, raising concern in the medical community due to its broad spectrum of antimicrobial resistance. Since it is a subject that arouses

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Are platelet indices useful in the evaluation of type 2 diabetic patients?

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 2 / cadmin

Kamilla R. Alhadas; Sandra N. Santos; Marcela Mara S. Freitas; Sophia Mara S. A. Viana; Luiz Cláudio Ribeiro; Mônica B. CostaJ. Bras. Patol. Med. Lab. 2016;52(2):96-102DOI: 10.5935/1676-2444.20160017 ABSTRACT INTRODUCTION: Long-term complications of diabetes mellitus are a leading cause of death in people with diabetes. Recent studies suggest that platelets with altered morphology could be associated with an increased

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Blood samples showing lipemia A) lipemic serum sample; B) whole blood sample after centrifugation, TG 12,355 mg/dl concentration. TG: triglycerides.

Procedures to minimize interference of hypertriglyceridemia in laboratory exams of lipemic samples in acute pancreatitis: a case report

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 2 / cadmin

Nívea Nara N. Andrade; Marcio V. Oliveira; Claudio L. SouzaJ. Bras. Patol. Med. Lab. 2016;52(2):103-106DOI: 10.5935/1676-2444.20160022 ABSTRACT Lipemia can be characterized by serum turbidity caused by accumulation of lipoproteins and is a major cause of interference in laboratory analyzes. Hypertriglyceridemia (HTG) is the third most common cause of acute pancreatitis (AP). Diagnosis and laboratory monitoring

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Illustrative images of some morphological criteria for the diagnosis of prostate cancer

Frequency of the morphological criteria of prostate adenocarcinoma in 387 consecutive prostate needle biopsies: emphasis on the location and number of nucleoli

Article Type, Issue, Pathology, Vol 52, Issue 2 / cadmin

Andrea O. Cruz; Amanda L. S. Santana; Andréia C. Santos; Daniel A. AthanazioJ. Bras. Patol. Med. Lab. 2016;52(2):107-111DOI: 10.5935/1676-2444.20160018 ABSTRACT INTRODUCTION AND OBJECTIVES: We evaluated the sensitivity and specificity of morphological criteria for the diagnosis of prostate adenocarcinoma in consecutive, prostate needle biopsies specimens with emphasis on the location and number of nucleoli.METHODS: The morphological features of

Frequency of the morphological criteria of prostate adenocarcinoma in 387 consecutive prostate needle biopsies: emphasis on the location and number of nucleoli Read More »

Clinical aspect of patient with metastatic cutaneous Crohn's disease: erythematous scaly plates in left arm

Metastatic cutaneous Crohn’s disease as an important differential diagnosis of granulomatous skin disease

Article Type, Issue, Pathology, Vol 52, Issue 2 / cadmin

Murilo C. Peretti; Andressa T. Szczypkovski; Gabriel S. Reis; Gabriela M. Quadros; Maira M. Mukai; Heda Maria B. S. Amarante; Betina WernerJ. Bras. Patol. Med. Lab. 2016;52(2):112-11510.5935/1676-2444.20160013 ABSTRACT Patients with Crohn’s disease may show extraintestinal manifestations, including cutaneous, whose frequency ranges from 2% to 34%. Metastatic cutaneous Crohn’s disease is considered a specific and rare

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A) numerous isolated cells in the basal layer, in a continuous pattern, labeled with Melan-A, mimicking melanoma in situ; B) S100 stain highlighted junctional melanocytes as well as langerhans cells in the epidermis; C and D) a normal number of melanocytes labeled with HMB45 (C) and tyrosinase (D)

Report of two cases of vacuolar interface dermatitis initially suspected as melanoma in situ and review of the literature

Article Type, Issue, Pathology, Vol 52, Issue 2 / cadmin

Luciana Pantaleão; Rosane Orofino-Costa; Mariléia C. Torres; Rossitza Lazova; Mayra C. RochaelJ. Bras. Patol. Med. Lab. 2016;52(2):116-119DOI: 10.5935/1676-2444.20160015 ABSTRACT The diagnosis of melanocytic lesions can be challenging and immunohistochemical study is a valuable tool for dermatopathologists. We report two cases initially simulating melanoma in situ, reviewing the histopathological and immunohistochemical findings and the cases published in

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