Vol 52, Issue 1 – Brazilian Journal of Pathology and Laboratory Medicine

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Telepathology: a new tool for medical education and recruitment and training of pathologists

Article Type, Editorial, Issue, Vol 52, Issue 1 / cadmin

Paulo Hilário Nascimento SaldivaJ. Bras. Patol. Med. Lab. 2016;52(1):4DOI: 10.5935/1676-2444.20160007 Pathology remains as one of the most important medical specialties, playing a pivotal role in diagnosis as well as in elucidating the pathogenesis of several diseases. Pathologists usually build a bridge between basic sciences and clinical practice, and are important players in translational biomedical research. […]

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epresentation of average HbF level in genotypes F: fetal; HbF-M: mean fetal hemoglobin; ATP: atypical; BEN: Benin; CAR: Central African Republic; p < 0.05.

Haplotypes βs-globin and its clinical-haematological correlation in patients with sickle-cell anemia in Triângulo Mineiro, Minas Gerais, Brazil

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 1 / cadmin

Alexandra S. Leal; Paulo Roberto J. Martins; Marly Aparecida S. Balarin; Gilberto A. Pereira; Gláucia Aparecida D. ResendeJ. Bras. Patol. Med. Lab. 2016;52(1):5-10DOI: 10.5935/1676-2444.20160001 ABSTRACT INTRODUCTION: Sickle-cell anemia (SCA) is the most severe form of sickle-cell disease, and is characterized by homozygous hemoglobin S (α2βS2).OBJECTIVE: Determine the haplotypes frequency in patients with SCA and their correlation with

Haplotypes βs-globin and its clinical-haematological correlation in patients with sickle-cell anemia in Triângulo Mineiro, Minas Gerais, Brazil Read More »

Analysis of the frequency of biological sample recollections as quality indicators in a clinical laboratory of Distrito Federal, Brazil

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 1 / cadmin

Natani L. Coriolano; Izabel Cristina R. Silva; Thaís A. C. LamounierJ. Bras. Patol. Med. Lab. 2016;52(1):11-16DOI: 10.5935/1676-2444.20160002 ABSTRACT INTRODUCTION: Clinical laboratory results influence more than 60% of medical decisions, impacting on disease prevention, diagnosis, and treatment. The use of quality indicators (QIs) is fundamental for quality assurance, once it allows monitoring the process and directs the

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The critical value concept in clinical laboratory

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 1 / cadmin

Bruna Cláudia B. Rocha; José Adilson R. Alves; Félix Pedro D. Pinto; Maria Elizabete Mendes; Nairo M. SumitaJ. Bras. Patol. Med. Lab. 2016;52(1):17-20DOI: 10.5935/1676-2444.20160008 ABSTRACT The critical value is a laboratory result representing a pathophysiological state that offers risk to a patient’s life. The communication of these results is a laboratory responsibility and, according to

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Allele frequencies for C282Y and H63D mutations

Prevalence of C282Y and H63D mutations in the HFE gene in patients from São Paulo and Southern Brazil

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 1 / cadmin

Marcos E. Herkenhoff; Ana Kelly Pitlovanciv; Vanessa R. RemualdoJ. Bras. Patol. Med. Lab. 2016;52(1):21-24DOI: 10.5935/1676-2444.20160003 ABSTRACT Hereditary hemochromatosis (HH) is an autosomal recessive disorder caused by mutations in the HFE gene; it is characterized by the risk of iron overload. C282Y and H63D are the most associated mutations in HH. This study aimed to determine the frequency

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Presence of koilocytes in UC. A and B: 20×; C and D: 40×, optical microscopy, Papanicolaou staining. Images by Leon, RM UC: urine cytology test.

Immunosuppression and the occurrence of HPV in kidney transplant patients verified by urinary cytology

Article Type, Cytopathology, Issue, Vol 52, Issue 1 / cadmin

Rogéria M. Leon; Alana D. Ranzi; Graziele S. Fardin; Elizete Keitel; Rosicler Luzia Brackmann; João Carlos Prolla; Claudia G. BicaJ. Bras. Patol. Med. Lab. 2016;52(1):25-30DOI: 10.5935/1676-2444.20160009 ABSTRACT INTRODUCTION: Human papillomavirus (HPV) is the main cause of cervical cancer, and immunosuppression is recognized as a risk factor for HPV infection and its persistence. After renal transplantation, immunosuppressive

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Aggressive papillary tumor of endolymphatic sac: CT showing an expansile lytic lesion arising in the right temporal bone (A and B) CT: computed tomography.

Aggressive papillary tumor of endolymphatic sac: case report of a rare neoplasia

Article Type, Issue, Pathology, Vol 52, Issue 1 / cadmin

Eduardo Cambruzzi; Karla Lais Pêgas; Leandro P. Almeida; Gerson Evandro Perondi; Leandro I. DiniJ. Bras. Patol. Med. Lab. 2016;52(1):31-34DOI: 10.5935/1676-2444.20160010 ABSTRACT Aggressive papillary endolymphatic sac tumor (ELST) is a rare neoplasm, occasionally related to von Hippel-Lindau disease, characterized by locally aggressive growth with temporal bone destruction. The authors report a case of ELST in a

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AAM in HE staining revealing a fragment of squamous mucosa with spindlecell neoplastic proliferation in loose collagenous stroma with a myxoid matrix embedding irregular vessels and inflammatory cells. A) 40×; B) 100×; C) 400×; D) 400× AAM: aggressive angiomyxoma; HE: hematoxylin and eosin.

Aggressive angiomyxoma of the vagina: a case report

Article Type, Issue, Pathology, Vol 52, Issue 1 / cadmin

Matheo Augusto M. Stumpf; Rebecca S. M. Stival; Alexandre B. Merlini; Fábio P. Mansani; Janicelli B. C. H. Silvestre; Isabela B. Mongruel; Mário R. Montemór NettoJ. Bras. Patol. Med. Lab. 2016;52(1):35-38DOI: 10.5935/1676-2444.20160011 ABSTRACT Aggressive angiomyxoma (AAM) is a rare infiltrative tumor of mesenchymal origin that has high rates of local recurrence. We present the case

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Erythematous keratotic papules arranged in a semi-circular pattern in the neck

Elastosis perforans serpiginosa, a transepithelial elimination skin disease diagnosed by histopathology: case report

Article Type, Issue, Pathology, Vol 52, Issue 1 / cadmin

Alexandre M. Lima; Milena M. Rodrigues; Sheila P. Rocha; Cibele C. Rodrigues; Carmelia M. S. ReisJ. Bras. Patol. Med. Lab. 2016;52(1):39-42DOI: 10.5935/1676-2444.20160004 ABSTRACT Elastosis perforans serpiginosa is a disease that belongs to the group of perforating dermatoses, in which dermal elastic tissue extrusion occurs through epidermis. It generally affects young male individuals, and is clinically

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Electrophoresis in 8% polyacrylamide gel stained with silver nitrate. HPV amplification (142 bp) HPV: human papillomavirus; MW: 100 bp DNA ladder; HeLa: DNA from HPV 18-infected cervical carcinoma cell line; CO2: condyloma DNA; NO: no DNA control; DNA: deoxyribonucleic acid; MW: molecular weight.

HPV detection in floor of mouth squamous cell carcinoma by PCR amplification

Article Type, Issue, Pathology, Vol 52, Issue 1 / cadmin

Luciana E. Simonato; Saygo Tomo; José Fernando Garcia; Luiz Alberto Veronese; Glauco I. MiyaharaJ. Bras. Patol. Med. Lab. 2016;52(1):43-49DOI: 10.5935/1676-2444.20160005 ABSTRACT INTRODUCTION: Studies conducted during the last years, using new technologies for viral detection, permit to consider human papillomavirus (HPV) an etiologic factor for cervical cancer. Besides the relation to genital regions, other anatomic sites have

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