Amplification of microsatellite regions using the multiplex PCR technique PCR: polymerase chain reaction; LOH: loss of heterozygosity.

Molecular biology techniques for loss of heterozygosity detection: the glioma example

Article Type, Issue, Pathology, Vol 51, Issue 3 /

Tiago D. P. Ramos; Lidia M. F. AmorimJ. Bras. Patol. Med. Lab. 2015;51(3):189-196DOI:10.5935/1676-2444.20150033 ABSTRACT In recent years, many oncology institutions have implemented the use of molecular approaches to assess and manage cancer patients. One commonly observed type of genetic alteration in cancer is the loss of heterozygosity (LOH). In the clinical setting, this molecular genetic […]

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