Brazilian Journal of Pathology and Laboratory Medicine

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Issue

Complications of idiopathic thrombocytopenic purpura in pregnancy: a review of literature

Camila L. Silva; Allyne Cristina GrandoJ. Bras. Patol. Med. Lab. 2021;57(1):1-9 ABSTRACT INTRODUCTION: Idiopathic thrombocytopenic purpura (ITP) is an acquired immune disorder that causes a reduction in platelet count, called thrombocytopenia. ITP during pregnancy usually presents some complications that may impair the outcome of pregnancy.OBJECTIVE: This literature review aimed to identify the main complications of ITP in […]

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

The influence of tobacco and alcohol in oral cancer: literature review

Rafaella B. Leite; Ana Carla O. Marinho; Beatriz L. Costa; Maria Beatriz V. Laranjeira; Kleyber D. T. Araújo; Anaícla F. M. CavalcantiJ. Bras. Patol. Med. Lab. 2021;57(1):1-5 ABSTRACT In Brazil, smoking and drinking are more common in male patients, less frequently affecting female patients. The most diagnosed type of lesion is squamous cell carcinoma. This

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Evaluation of galectin-3 levels in patients with type 2 diabetes mellitus and chronic kidney disease

Isabella D. P. Souza; Kathryna F. Rodrigues; Nathália T. Pietrani; Adriana A. Bosco; Karina B. Gomes; Michelle T. AlvesJ. Bras. Patol. Med. Lab. 2021;57(1):1-9 ABSTRACT INTRODUCTION: Type 2 diabetes mellitus (T2DM) is the most common manifestation of diabetes, accounting for about 90% of diagnosed cases. The causes of T2DM are not fully understood, but its pathogenesis

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Pie charts showing percentages of patients with CTCs detected by analyses of the expression of TWIST-1, MGA and the combination of expression of both genes CTCs: circulating tumor cells.

The combination of mammaglobin A and TWIST-1 increases detection of circulating tumor cells in breast cancer

Georgina Gallucci; Estefanía Massa; Carlos C. Funes; Roberto Tozzini; Sergio Ghersevich J. Bras. Patol. Med. Lab. 2021;57(1):1-10 ABSTRACT OBJECTIVES: Breast cancer cells that are released into the bloodstream are called circulating tumor cells (CTCs). CTCs can express different genes, like TWIST-1 and mammaglobin A (MGA). The aims of this study were to analyze the expression of TWIST-1 and MGA in the blood

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Distribuição dos valores medianos de testosterona total com os participantes da coleta realizando ou não jejum de 8 horas

Evaluation of the influence of pre-analytical factors on total testosterone levels in healthy young men

Isabela L. Lima; Isabelly M. Neves; Izabela R. Costa; Matheus C. Caplum; Pedro C. B. Oliveira; Rômulo C. Vaz de Mello J. Bras. Patol. Med. Lab. 2021;57(1):1-6 DOI: 10.5935/1676-2444.20210016 Evaluation of the influence of pre-analytical factors on total testostero ABSTRACT INTRODUCTION: Testosterone is the main hormone that regulates male reproductive functions, directly participating in spermatogenesis and

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Relationship between serum concentrations of uric acid, insulin resistance and metabolic alterations in adolescents

Malene L. G. Sodré; Alice S. Ferreira; Andressa C. Ferreira; Anne Caroline S. Silva; Carla Milena A. Sá; Carlos Alberto D. Filho; Sally Cristina M. Monteiro J. Bras. Patol. Med. Lab. 2021;57(1):1-7DOI: 10.5935/1676-2444.20210020 ABSTRACT OBJECTIVE: To verify the possible relationship between serum uric acid concentrations and insulin resistance in adolescents.METHODS: This is a cross-sectional study with 74

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Fotomicrografias de imunomarcação para TIMP-1 em CCE

Analysis of TIMP-1 expression in leukoplakia and oral squamous cell carcinoma

Susy Carmelita P. Nascimento; Letícia N. G. Souza; Liliana Aparecida P. Barros J. Bras. Patol. Med. Lab. 2021;57(1):1-11 ABSTRACT INTRODUCTION: The current study about transition of oral epithelial dysplasia, present in lesions such as leukoplakia, for squamous cell carcinoma (SCC) involves not only the histopathological aspects, but also the analysis of the presence of biomarkers which

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Follow-up of squamous atypia’s and the evaluation of the conducts according to the recommendations of the Ministry of Health

Mateus F. Delabeneta; Dayane B. Costa; Jacqueline Plewka; Maiara Aline Santos; Maurício TurkiewiczJ. Bras. Patol. Med. Lab. 2021;57(1):1-7DOI: 10.5935/1676-2444.20210028 ABSTRACT INTRODUCTION: Cervical cancer is considered a public health problem, ranking fourth among the most common types of cancer worldwide.OBJECTIVE: The present study aimed to gather information on the follow-up, and to verify adherence to the management recommended

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Impact of pre-analytical errors on costs of clinical analysis laboratory

Priscila R. Santos; Camila L. Silva; Magda C. Gall; Allyne Cristina GrandoJ. Bras. Patol. Med. Lab. 2021;57(1):1-5DOI: 10.5935/1676-2444.20210023 ABSTRACT INTRODUCTION: Currently, it is well known that quality assurance systems in healthcare organizations are constantly evolving. Quality improvements can reduce costs by avoiding repetition of exams, which results in a waste of time and money for the

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Rumack-Matthew Nomogram(11)

Use of different matrices to construct the standard curve for the paracetamol dosage by visible spectrophotometry

Caroline M. Barros; Andresa P. Silva; Juliana O. S. S. Mizael; Yoko Oshima-FrancoJ. Bras. Patol. Med. Lab. 2021;57(1):1-7 ABSTRACT INTRODUCTION: Acute paracetamol poisoning is confirmed by the determination of its serum level and allows assessing the risk of hepatotoxicity, which can be monitored by the Rumack-Matthew nomogram for the administration of the N-Acetylcysteine antidote, as well

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