Brazilian Journal of Pathology and Laboratory Medicine

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Immunostaining for anti-smooth muscle actin antibodies (10× objective lens)

Multicentric angiomyolipoma in kidney, liver, and lymph node: case report/review of the literature

Article Type, Issue, Pathology, Vol 51, Issue 3 /

Artur S. de Azevedo; Nábia Maria M. S. SimãoJ. Bras. Patol. Med. Lab. 2015;51(3):173-177DOI:10.5935/1676-2444.20150030 ABSTRACT INTRODUCTION: The angiomyolipoma (AML) is constituted by adipose tissue, blood vessels and smooth muscle fiber; follows a benign clinical course, with slow growth and absence of metastasis, occurring in tuberous sclerosis or sporadically.OBJECTIVE: We intend to describe the clinical, radiological and histological […]

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Histological section of jejunum with transmural coagulative necrosis, HE 100× HE: hematoxylin and eosin.

Fatal complication after transsphenoidal surgery of pituitary adenoma: case report

Article Type, Issue, Pathology, Vol 51, Issue 3 /

Conceição Aparecida Dornelas; Tereza N. A. G. Nogueira; Evandro T. Alves; River A. B. CoêlhoJ. Bras. Patol. Med. Lab. 2015;51(3):178-182DOI:10.5935/1676-2444.20150031 ABSTRACT The objective of this study was to report a rare fatal complication in the postoperative period of transsphenoidal surgery of the pituitary gland (adenoma), with a brief review of the subject. The patient was

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Puncture tracheotomy in BALB/c lineage mice

Access to the tracheal pulmonary pathway in small rodents

Article Type, Issue, Pathology, Vol 51, Issue 3 /

Roberto S. A. Ribeiro; Isabeliza M. E. S. R. Ferreira; Israel Figueiredo Jr; Maurício A. VerícimoJ. Bras. Patol. Med. Lab. 2015;51(3):183-188DOI:10.5935/1676-2444.20150032 ABSTRACT The tracheal pulmonary route is used in diverse experimental models for the study of drugs, infectious agents, and diseases. In view of its importance and associated difficulties, the present article proposes to give

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Amplification of microsatellite regions using the multiplex PCR technique PCR: polymerase chain reaction; LOH: loss of heterozygosity.

Molecular biology techniques for loss of heterozygosity detection: the glioma example

Article Type, Issue, Pathology, Vol 51, Issue 3 /

Tiago D. P. Ramos; Lidia M. F. AmorimJ. Bras. Patol. Med. Lab. 2015;51(3):189-196DOI:10.5935/1676-2444.20150033 ABSTRACT In recent years, many oncology institutions have implemented the use of molecular approaches to assess and manage cancer patients. One commonly observed type of genetic alteration in cancer is the loss of heterozygosity (LOH). In the clinical setting, this molecular genetic

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Detection of H. pylori in endoscopic gastric biopsies: a routine research that goes far beyond the laboratory limits

Article Type, Editorial, Issue, Vol 51, Issue 2 /

Alfredo J. A. BarbosaJ. Bras. Patol. Med. Lab. 2015;51(2):70-71DOI:10.5935/1676-2444.20150012 ABSTRACT Instituto Alfa de Gastroenterologia; Hospital das Clínicas da Universidade Federal de Minas Gerais, Belo Horizonte, Brasil It took about 10 years between the first reports of the association of the microorganism H. pylori with inflammation of the gastric mucosa and the acceptance by the scientific community of

Detection of H. pylori in endoscopic gastric biopsies: a routine research that goes far beyond the laboratory limits Read More »

AML subtypes in children aged 0 to 17 years

Frequency of acute myeloid leukemia in children attended in Belém, Pará from August 2005 to May 2009

Article Type, Editorial, Issue, Vol 51, Issue 2 /

Lacy C. B. Junior; Ian E. Levy; Larissa Tatiana V. M. Frances; Alayde V. Wanderley; Rita de Cássia M. Carneiro; Alessandra Q. BentesJ. Bras. Patol. Med. Lab. 2015;51(2):72-76DOI:10.5935/1676-2444.20150013 ABSTRACT INTRODUCTION: Acute myeloid leukemia (AML) has variable incidence in different regions of Brazil.OBJECTIVE: To determine the frequency of AML subtypes in children aged 0-17 years attended at Belém,

Frequency of acute myeloid leukemia in children attended in Belém, Pará from August 2005 to May 2009 Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

New red blood cell and reticulocyte parameters and reference values for healthy individuals and in chronic kidney disease

Article Type, Issue, Laboratory Medicine, Vol 51, Issue 2 /

Patrícia S. Scherer; Daniela Moraes; Terezinha P. Munhoz; Vanessa SgnaolinJ. Bras. Patol. Med. Lab. 2015;51(2):77-84DOI:10.5935/1676-2444.20150014 ABSTRACT INTRODUCTION: The importance of local references values has been well described in the literature; this is because the characteristics of the population may influence the laboratory tests.OBJECTIVE: To establish the reference range for traditional and extended red blood cell parameters and

New red blood cell and reticulocyte parameters and reference values for healthy individuals and in chronic kidney disease Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Hematological parameters in children with Down syndrome

Article Type, Issue, Laboratory Medicine, Vol 51, Issue 2 /

Renato Nisihara; Alana S. C. Souza; Letícia R. Finatti; Nancy O. PalmieriJ. Bras. Patol. Med. Lab. 2015;51(2):85-90DOI:10.5935/1676-2444.20150015 ABSTRACT INTRODUCTION: There are few studies that investigated whether Down syndrome (DS) interferes with references values for complete blood counts (CBC) test in children with the syndrome.OBJECTIVE: This study aimed to analyze the results of CBC performed in children with

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Distribution of log10 (OD/CO) for DBS HIV reactive and non-reactive samples OD: optical density; CO: cut-off; δ: delta value; DBS: dried blood spot; HIV: human immunodeficiency virus.

Blood collection on filter paper for HIV antibodies detection: experience of SampaCentro Project

Article Type, Issue, Laboratory Medicine, Vol 51, Issue 2 /

Marcia J. Castejon; Rosemeire Yamashiro; Carmem A. F. Oliveira; Carmen Lúcia Soares; Maria Amélia S. M. VerasJ. Bras. Patol. Med. Lab. 2015;51(2):91-98DOI:10.5935/1676-2444.20150016 ABSTRACT INTRODUCTION: Blood samples collected on filter paper (dried blood spot [DBS]) is an immunoassay that has been used for antibodies screening.OBJECTIVE: To evaluate the strategy of DBS blood collection for detection of HIV antibodies,

Blood collection on filter paper for HIV antibodies detection: experience of SampaCentro Project Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Absence of atypical haplotype and presence of Senegal haplotype sickle cell disease in African-descent population in the northern Brazil

Article Type, Issue, Pathology, Vol 51, Issue 2 /

Rafael E. Nascimento; Natália M. Castelo; Adriana C. Bueno; Larissa Mescouto; Artemis S. N. RodriguesJ. Bras. Patol. Med. Lab. 2015;51(2):99-101DOI:10.5935/1676-2444.20150017 ABSTRACT INTRODUCTION: Sickle cell anemia (SCA) is the most severe form of sickle cell disease; it presents variants that are called haplotypes βS. There are five major haplotypes βS gene: Arab-Indian/Saudi, Senegal, Benin, Bantu, and Camaroon.OBJECTIVE: Characterize the

Absence of atypical haplotype and presence of Senegal haplotype sickle cell disease in African-descent population in the northern Brazil Read More »