Brazilian Journal of Pathology and Laboratory Medicine

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Prevalence of factor V Leiden in patients with venous thrombosis

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 4 /

Cristiane Aparecida Michel; Julia B. Rocha; Daiane C. Costa; Carlos Augusto Lima; Anna Paula B. BatschauerJ. Bras. Patol. Med. Lab. 2016;52(4):227-232DOI: 10.5935/1676-2444.20160038 ABSTRACT INTRODUCTION: Venous thrombosis is a multifactor disease with high incidence in the population. The development of this disease is closely linked to the presence of environmental and genetic factors and may occur in […]

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Species distribution and antifungal susceptibility to vulvovaginal Candida spp. in southern Mato Grosso State, Brazil

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 4 /

Letícia S. Goulart; Elicléia F. Santiago; Júlia L. Ramon; Selma V. Moura; Amanda R. Silva; Iberê F. Silva Jr; Juliana Helena Chávez-Pavoni; Claudinéia AraújoJ. Bras. Patol. Med. Lab. 2016;52(4):233-237DOI: 10.5935/1676-2444.20160039 ABSTRACT INTRODUCTION: Vulvovaginal candidiasis is a prevalent opportunistic mucosal infection, caused predominantly by Candida albicans. Candida species vary in their susceptibility to the antifungal agents, thus, the susceptibility

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Cervical cancer screening: from Pap smear to future strategies

Article Type, Cytopathology, Issue, Vol 52, Issue 4 /

Cristina Aparecida T. S. MitteldorfJ. Bras. Patol. Med. Lab. 2016;52(4):238-245DOI: 10.5935/1676-2444.20160040 ABSTRACT Previously, the screening for detection of cervical cancer was performed by simple cervicovaginal sample collected by the physician whenever the patient attended the medical consultation, and soon it was established as the annual “Pap smear”. Since then, an elementary test has evolved into

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Histological panoramic view of prostate tissue

Features of the female prostate according to age: an autopsy study

Article Type, Issue, Pathology, Vol 52, Issue 4 /

Thalita Cristina M. Costa; Patrícia M. Cury; Ana Maria G. CustódioJ. Bras. Patol. Med. Lab. 2016;52(4):246-252DOI: 0.5935/1676-2444.20160041 ABSTRACT INTRODUCTION: The prostate gland plays an important role in male and female reproductive system. Data on this organ have not been fully explored in women since its first description, probably because it is considered a vestigial gland.OBJECTIVE: To correlate

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Photomicrograph of groups

Quantitative analysis of inflammatory and adhesion molecules in lungs of neonates with chronic lung disease (bronchopulmonary dysplasia) receiving mechanical ventilation

Article Type, Issue, Pathology, Vol 52, Issue 4 /

Cristina T. Okamoto; Carlos F. Oldenburg Neto; Sandra Mara Witkowski; Ana Paula Percicote; Luca R. Pasqualotto; Gabriela Troiano; Tammy Almeida; Cleber M. Souza; Lúcia de NoronhaJ. Bras. Patol. Med. Lab. 2016;52(4):253-261DOI: 10.5935/1676-2444.20160042 ABSTRACT INTRODUCTION: Chronic lung disease (CLD), clinically known as bronchopulmonary dysplasia (BPD), is a major cause of morbidity in premature newborn and were submitted

Quantitative analysis of inflammatory and adhesion molecules in lungs of neonates with chronic lung disease (bronchopulmonary dysplasia) receiving mechanical ventilation Read More »

Morphological and immunohistochemical characteristics of the resected specimens A) urothelial papillary neoplasia, HE 20×; B) invasive urothelial carcinoma with discohesive growth pattern, HE 200×; C) tumor cells showed eosinophilic cytoplasm and visible nucleoli, often with intracytoplasmic vacuoles and peripheral nucleus, HE 400×; D) negative for E-cadherin staining, 200×. HE: hematoxylin and eosin.

Invasive bladder urothelial carcinoma, plasmacytoid variant: case report

Article Type, Issue, Pathology, Vol 52, Issue 4 /

Rui Pedro C. M. Oliveira; Carlos Filipe C. Abrantes; Edgar Miguel C. T. Silva; Carol A. Marinho; Vítor Manuel L. Sousa; Lígia R. C. O. A. P. CastroJ. Bras. Patol. Med. Lab. 2016;52(4):262-265DOI: 10.5935/1676-2444.20160043 ABSTRACT Invasive bladder urothelial carcinoma, plasmacytoid variant is a rare entity with scarce cases reported in the literature. We report a

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Photomicrograph showing areas with mucinous differentiation in urethral adenocarcinoma (100×). In detail (right and below), neoplastic cells with signet-ring appearance (400×)

Adenocarcinoma of the female urethra: a case report

Article Type, Issue, Pathology, Vol 52, Issue 4 /

José de Carvalho Neto; Sydney C. Leão; Ricardo Fakhouri; Roberto Gurgel; Julia Maria G. Dias; Nivaldo F. VieiraJ. Bras. Patol. Med. Lab. 2016;52(4):266-269DOI: 10.5935/1676-2444.20160044 ABSTRACT The urethral adenocarcinoma is a rare malignant tumor that affects predominantly women. Its incidence is higher after the age of 50 in this group. The knowledge about this disease is

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Platelet interference in automated reticulocyte counting

Article Type, Editorial, Issue, Vol 52, Issue 3 /

Thales Gouveia LimeiraJ. Bras. Patol. Med. Lab. 2016;52(3):136DOI: 10.5935/1676-2444.20160027 Retired professor from Universidade Federal do Espírito Santo (Ufes), Espírito Santo, Brazil; Faculdade Multivix, Espírito Santo, Brazil Medicine has gone through an admirable improvement due to the arsenal of resources offered by scientific advancement, what allows for prolongation of life and the enhancement of its quality.

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Performance of anti-AF antibodies to distinguish secondary Sjögren's syndrome in RA patients A) ROC of anti-AF IgA with area = 0.502 (95% CI = 0.38-0.62); p = 0.96; B) ROC of anti- AF IgG with area = 0.52 (95% IC = 0.4-0.64); p = 0.67. AF: alpha-fodrin; RA: rheumatoid arthritis; ROC: receiver operating characteristic; IgA: immunoglobulin class A; CI: confidence interval; IgG: immunoglobulin class G.

Anti-alpha-fodrin antibodies in patients with Sjögren’s syndrome secondary to rheumatoid arthritis

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 3 /

Renato Nisihara; Thelma L. Skare; Elisa Cenci; Denise Gabardo; Flavia Nass; Shirley R. R. UtiyamaJ. Bras. Patol. Med. Lab. 2016;52(3):137-141DOI: 0.5935/1676-2444.20160023 ABSTRACT INTRODUCTION: The Sjögren’s syndrome (SS) is an autoimmune disease characterized by lymphocytic infiltration. The currently most researched antibodies for its diagnosis are anti-La and anti-Ro, which, however, have low specificity in the case of

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Strategy of analysis for reticulocyte count by FC/TO and CD61PE A) selection of the population of interest, R1, based on morphometric aspects for the construction of graph B (FL1 × anti-CD61PE/FL2); B) identification of the homogeneous population, R2, and possible interferents - R3 and R4; C) quantification of the percentage of positive cells in the upper right quadrant (stained with TO) present in the R2 region - graph drawn with the combination of gates in R1 and R2 regions. FC/TO: method of reticulocyte count by flow cytometry, using thiazole orange; SSC: side scatter; FSC: forward scatter.

Evaluation of the interference of platelets in reticulocyte counting by flow cytometry using thiazole orange

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 3 /

Karina Augusta Viana; Olindo A. Martins Filho; Luci Maria S. Dusse; Lis R. V. Antonelli; Danielle M. V. Avelar; Renato S. Avelar; Maria das Graças CarvalhoJ. Bras. Patol. Med. Lab. 2016;52(3):142-148DOI: 10.5935/1676-2444.20160025 ABSTRACT INTRODUCTION: The reticulocyte count by flow cytometry (FC) – an automated counting method – can present errors due to the presence of interfering

Evaluation of the interference of platelets in reticulocyte counting by flow cytometry using thiazole orange Read More »