Brazilian Journal of Pathology and Laboratory Medicine

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Issue

Analysis of necrotic areas

Daily intake of watercress causes inhibition of experimental Ehrlich tumor growth

Débora Aparecida de Souza; Poliane M. Costa; Rosy Iara M. A. Ribeiro; Paula V. T. Vidigal; Flávia C. H. PintoJ. Bras. Patol. Med. Lab. 2016;52(6):393-399DOI: 10.5935/1676-2444.20160063 ABSTRACT INTRODUCTION: Increasing cruciferous vegetable intake has been associated with reduced risk of cancer. Experimental and epidemiological studies suggest that the watercress it is a cruciferous vegetable with high concentration […]

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Photomicrography, stained with HE, of the skeletal musculature of BALB/c mice after implantation of Linnea Safe

Polymethyl methacrylate (Linnea Safe) causes local inflammatory response after intramuscular implant in BALB/c mice but it is not observed in distant organs

Eduardo Luiz Costa; Anália C. Milhomem; Ronaldo Moisés de Moura Filho; Ruy S. Lino Jr.J. Bras. Patol. Med. Lab. 2016;52(6):400-406DOI: 10.5935/1676-2444.20160058 ABSTRACT INTRODUCTION: Among its different therapeutic functions, the use of polymethyl methacrylate (PMMA) for more than a decade has has stood out in the replacement of the volumes lost with the aging process and filling

Polymethyl methacrylate (Linnea Safe) causes local inflammatory response after intramuscular implant in BALB/c mice but it is not observed in distant organs Read More »

Immunohistochemical reaction

Immunohistochemical analysis of apoptosis and cell proliferation in lungs of premature infants with chronic lung disease (bronchopulmonary dysplasia)

Sandra Mara Witkowski; Lúcia de Noronha; Cristina T. Okamoto; Carlos F. Oldenburg Neto; Tammy Almeida; Seigo Nagashima; João A. BahrJ. Bras. Patol. Med. Lab. 2016;52(6):407-415DOI: 10.5935/1676-2444.20160064 ABSTRACT INTRODUCTION: The pathophisiology of chronic lung disease (CLD), clinically known as bronchopulmonary dysplasia is not clear. It is believed that protective mechanisms, such as the release of inflammatory mediators

Immunohistochemical analysis of apoptosis and cell proliferation in lungs of premature infants with chronic lung disease (bronchopulmonary dysplasia) Read More »

ISH Sample number 30 (lymph node) labeled by the five probes A-E. A-E) positive cells are labeled in brown or purple (bold arrows); F) RNA negative probe. Original magnification 400× from A to F. ISH: in situ hybridization; RNA: ribonucleic acid.

Comparative study of five commercial probes for the detection of Epstein-Barr virus (EBV) by in situ hybridization in cases of nodular sclerosis Hodgki’s lymphoma

Suely Nonogaki; Neuza K. Shirata; Lidia M. Kimura; Juliana M. Guerra; Raphael S. S. Medeiros; Roberto Antonio P. Paes; Cristina T. Kanamura; Camila C. Oliveira; Yara de MenezesJ. Bras. Patol. Med. Lab. 2016;52(6):416-425DOI: 10.5935/1676-2444.20160065 ABSTRACT INTRODUCTION: Epstein-Barr virus (EBV) may serve as a target in therapeutic treatments, thus reliable diagnostic results are necessary.OBJECTIVE: The aim of this

Comparative study of five commercial probes for the detection of Epstein-Barr virus (EBV) by in situ hybridization in cases of nodular sclerosis Hodgki’s lymphoma Read More »

Autopsy findings A) acute pneumonia with bacterial colonies; B) bacterial colony in the lung (highest increase) with suspicious histiocytic aggregates; C) suspected histiocytic aggregates in hepatic parenchyma; D) suspicious histiocytic aggregates in the gallbladder wall.

Multisystemic Langerhans cell histiocytosis: case report

Larissa A. Paiva; Daniela M. Takano; Valeska A. S. Queiroz; Laís S. PríncipeJ. Bras. Patol. Med. Lab. 2016;52(6):426-428DOI: 10.5935/1676-2444.20160066 ABSTRACT Langerhans cell histiocytosis is the designated name for a spectrum of rare diseases that affects children from one- to three-years-old, which name refers to the proliferation of cells morphologically and immunophenotypically similar to the specialized

Multisystemic Langerhans cell histiocytosis: case report Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Bacterial resistance in enterobacteria

Cecilia Godoy CarvalhãesJ. Bras. Patol. Med. Lab. 2016;52(5):282-283DOI: 10.5935/1676-2444.20160048 ABSTRACT The increase on antimicrobial resistance rates worldwide is a fact that has received great emphasis, not only in the scientific community, but also within the governmental, economic and social scope. In 2013, at the World Economic Forum in Davos, bacterial resistance was described as one

Bacterial resistance in enterobacteria Read More »

Antibiotic resistance genes detected in ESBL-producing K. pneumoniae ESBL: extended-spectrum beta-lactamases.

Detection of antimicrobial resistance genes in beta-lactamase- and carbapenemase-producing Klebsiella pneumoniae by patient surveillance cultures at an intensive care unit in Rio de Janeiro, Brazil

Claudia Flores; Célia Maria C. P. A. Romão; Kayo Bianco; Catia Chaia de Miranda; Angela Breves; Ana Paula S. Souza; Rosana Maria R. Santos; Bianca O. Fonseca; Ivano de Filippis; Maysa M. ClementinoJ. Bras. Patol. Med. Lab. 2016;52(5):284-292DOI: 10.5935/1676-2444.20160049 ABSTRACT INTRODUCTION: The increasing incidence of multi-resistant microorganisms has been considered a public health problem. One of

Detection of antimicrobial resistance genes in beta-lactamase- and carbapenemase-producing Klebsiella pneumoniae by patient surveillance cultures at an intensive care unit in Rio de Janeiro, Brazil Read More »

Prevalence of microorganisms isolated from PU exudate among internal medicine inpatients, Petrolina (PE) PU: pressure ulcer.

Biofilm production and resistance profile of Enterobacter sp. strains isolated from pressure ulcers in Petrolina, Pernambuco, Brazil

Gleise G. Soares; Joice F. Costa; Flávia B. S. Melo; Rachel Mola; Tereza Cristina L. BalbinoJ. Bras. Patol. Med. Lab. 2016;52(5):293-298DOI: 10.5935/1676-2444.20160045 ABSTRACT INTRODUCTION: The Enterobacter genus is formed by lactose-fermenting bacteria. These microorganisms cause a wide range of hospital infections such as pneumonia, urinary tract infections and wounds; and they are associated with the colonization of medical

Biofilm production and resistance profile of Enterobacter sp. strains isolated from pressure ulcers in Petrolina, Pernambuco, Brazil Read More »

Sample selection – flow chart Flow chart showing the process followed by every newborn in our institution and then used in the present study to select our study population.

Hemoglobinopathy detection through an institutional neonatal screening program in Colombia

Sandra Johanna Echeverry-Coral; Claudia Carolina Colmenares-Mejía; Zuli Ximena Yepes-Molina; Oscar Martínez-Nieto; Mario A. Isaza-RugetJ. Bras. Patol. Med. Lab. 2016;52(5):299-306DOI: 10.5935/1676-2444.20160050 ABSTRACT INTRODUCTION: Hemoglobinopathies are among the most common genetic disorders of hemoglobin worldwide and a public health problem. In Colombia, even though geographical areas with high incidence of this disorder have been reported, the absence of

Hemoglobinopathy detection through an institutional neonatal screening program in Colombia Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Report of a case of paroxysmal nocturnal hemoglobinuria (PNH) with complex evolution and liver transplant

Railene Célia B. Alencar; Andréa M. Guimarães; Lacy C. Brito JuniorJ. Bras. Patol. Med. Lab. 2016;52(5):307-311DOI: 10.5935/1676-2444.20160051 ABSTRACT The paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired disease, with thrombotic episodes and frequent pancytopenia. We report the case of a 32 year-old female PNH patient with bone marrow aplasia, which followed a complex course, diagnosed

Report of a case of paroxysmal nocturnal hemoglobinuria (PNH) with complex evolution and liver transplant Read More »