Brazilian Journal of Pathology and Laboratory Medicine

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Images of the patient at 10 years of age showing diffuse and irregular alopecia with hair rupture at different levels, giving an appearance of hypotrichosis (A and B)

Description of clinical aspects and microscopy of the hair shaft of a carrier of familial monilethrix

Article Type, Issue, Vol 54, Issue 5 /

Maria Angélica T. Ferreira; João Francisco O. Gonzales; Bruna L. Diniz; Maiara A. Floriani; Ana Elisa K. Bau; Rosana C. M. Rosa; Rafael Fabiano M. Rosa; Paulo Ricardo G. ZenJ. Bras. Patol. Med. Lab. 2018;54(5):333-335DOI:10.5935/1676-2444.20180055 ABSTRACT Monilethrix is a genetic condition that affects the hair shaft. We describe a family with this disease, focusing on […]

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The cysts were lined by cubic or flat epithelia, sometimes with hobnail cells

Cystic nephroma and DICER1 mutations: report of a hitherto unreported mutation

Article Type, Issue, Original Article, Vol 54, Issue 5 /

Rui Caetano Oliveira; Mónica Jerónimo; Alexandra Paúl; Carol Marinho; Fátima HeitorJ. Bras. Patol. Med. Lab. 2018;54(5):336-339DOI:10.5935/1676-2444.20180056 ABSTRACT Paediatric cystic nephroma is a neoplasm of uncertain pathogenesis characterized by a multilocular architecture that develops in children. Some cases may be sporadic, and others may present a familial association, together with other neoplasms, as part of a

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Yellow fever: laboratorial diagnosis and clinical manifestations

Article Type, Issue, Review Article, Vol 54, Issue 5 /

Analúcia R. Xavier; Gabriela S. Freitas; Caroline F. Santos; Werlley A. Januzzi; Gilmar S. Lacerda; Edimilson R. M. Carvalho; Salim KanaanJ. Bras. Patol. Med. Lab. 2018;54(5):296-305DOI:10.5935/1676-2444.20180050 ABSTRACT Yellow fever is an infectious disease of acute evolution, initially non-contagious, transmitted by a ribonucleic acid (RNA) virus that belongs to the Flaviviridae family. In the period from December 2016

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Sample transport validation: experience of a medium-sized laboratory

153 Comments / Article Type, Brief Communication, Issue, Vol 54, Issue 5 /

Vivianne A. Lopes; Juliana S. Silveira; Letícia B. S. Santos; Missilene da Conceição P. Nunes; Manuel S. FariaJ. Bras. Patol. Med. Lab. 2018;54(5):306-309DOI:10.5935/1676-2444.20180051 ABSTRACT INTRODUCTION: The adequacy of biological samples is a critical and important item in the clinical laboratory, so that reliable results can be obtained for patients.OBJECTIVE: To ensure integrity and stability of biological samples

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Transference of CALIPER total alkaline phosphatase reference interval to a Brazilian pediatric population

Article Type, Editorial, Issue, Vol 54, Issue 4 /

Natasha Slhessarenko; Adagmar AndrioloJ. Bras. Patol. Med. Lab. 2018;54(4):204-205DOI:10.5935/1676-2444.20180035 ABSTRACT The reference intervals (RI) represent a set of values used to interpret the results of quantitative laboratory tests and are powerful tools that assist health professionals in making decisions during patient care(1). The determination of their own RI gives diagnostic power, but it is one

Transference of CALIPER total alkaline phosphatase reference interval to a Brazilian pediatric population Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Evaluation of MALDI-TOF mass spectrometry (VITEK-MS) compared to the ANC card (VITEK 2) for the identification of clinically significant anaerobes

Article Type, Issue, Original Article, Vol 54, Issue 4 /

Eliane R. Tsukimoto; Flávia RossiJ. Bras. Patol. Med. Lab. 2018;54(4):206-212DOI:10.5935/1676-2444.20180036 RESUMO INTRODUÇÃO: A identificação das bactérias anaeróbias por métodos convencionais empregados nos laboratórios clínicos demanda muito trabalho e um longo tempo de resposta (TAT). A espectrometria de massa por ionização e dessorção a laser assistida por matriz (MALDI-TOF MS) é uma técnica precisa, rápida e barata,

Evaluation of MALDI-TOF mass spectrometry (VITEK-MS) compared to the ANC card (VITEK 2) for the identification of clinically significant anaerobes Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Oxidative, inflammatory and cardiometabolic biomarkers of clinical relevance in patients with metabolic syndrome

Article Type, Issue, Original Article, Vol 54, Issue 4 /

Eduardo O. Chielle; Fagner Gens; Eliandra M. RossiJ. Bras. Patol. Med. Lab. 2018;54(4):213-219DOI:10.5935/1676-2444.20180037 RESUMO INTRODUÇÃO: A obesidade caracteriza-se pela deposição excessiva de gordura no tecido adiposo e está associada ao desenvolvimento de danos patológicos em vários processos metabólicos que estão relacionados com o estresse oxidativo e a inflamação.OBJETIVO: Avaliar os níveis de adiponectina, marcadores inflamatórios e marcadores

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Procedure for choosing ICU and patients ICU: intensive care unit.

Review of peripheral blood smear slides: assessment of the compliance with criteria used by analysts in a laboratory of a public hospital in Bahia, Brazil

Article Type, Issue, Original Article, Vol 54, Issue 4 /

Anna Karla N. Souza; Palloma Grazielly M. Cordeiro; Cláudio L. Souza; Márcio V. OliveiraJ. Bras. Patol. Med. Lab. 2018;54(4):220-226DOI:10.5935/1676-2444.20180038 RESUMO INTRODUÇÃO: Recomendações em literatura e publicações de sociedades científicas têm proposto sistemas e níveis de classificação para comunicar alterações hematoscópicas no hemograma. Visando a uniformização dos resultados liberados no laboratório clínico, a padronização em hematoscopia apresenta-se

Review of peripheral blood smear slides: assessment of the compliance with criteria used by analysts in a laboratory of a public hospital in Bahia, Brazil Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Alkaline phosphatase: reference interval transference from CALIPER to a pediatric Brazilian population

Article Type, Issue, Original Article, Vol 54, Issue 4 /

Rosita Fontes; Emanuela Cavalari; Leonardo Vieira Neto; Yolanda Shrank; Antonio S. Santos; Dalva Margareth Gomes; Maria Fernanda C. Pinheiro; Paula Bruna M. C. AraujoJ. Bras. Patol. Med. Lab. 2018;54(4):227-231DOI:10.5935/1676-2444.20180039 RESUMO INTRODUÇÃO: A interpretação de exames laboratoriais necessita de intervalos de referência (IR) que podem variar entre diferentes populações. Para o diagnóstico de hipofosfatasia, deve-se determinar limites

Alkaline phosphatase: reference interval transference from CALIPER to a pediatric Brazilian population Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Assessment of the pre-analytical phase of a clinical analyses laboratory

Article Type, Issue, Original Article, Vol 54, Issue 4 /

Jéssica M. Martins; Elayne Cristina M. Rateke; Flávia MartinelloJ. Bras. Patol. Med. Lab. 2018;54(4):232-240DOI:10.5935/1676-2444.20180040 RESUMO INTRODUÇÃO: A fase pré-analítica abrange os procedimentos antes da execução dos testes laboratoriais, sendo eles a requisição, o cadastro de clientes e exames, a coleta e o transporte de amostras. Essa fase envolve diferentes profissionais e é responsável pela maioria dos

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