Brazilian Journal of Pathology and Laboratory Medicine

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Postnatal appearance of the fetus showing the umbilical cord attached to the cephalic pole, in the area cerebrovasculosa (A-C). Along with these structures the presence of a fibrous tissue (see arrow) was also identified, what raised the possibility of an amniotic band (C)

Fetal anencephaly with umbilical cord attached to cerebrovasculosa area: autopsy report

Stephan Philip L. Altmayer; McArthur Alex Barrow; Maiara A. Floriani; Glauco K. Nagata; Matheus Zanon; André C. Cunha; Paulo Renato Krahl Fell; Cristine Dietrich; Paulo Ricardo G. Zen; Rafael Fabiano M. RosaJ. Bras. Patol. Med. Lab. 2019;55(2):210-217DOI: 10.5935/1676-2444.20190012 ABSTRACT Our aim was to report the unusual case of an anencephalic fetus that was born with […]

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Immunohistochemistry: A) positive expression of CD99 marker; B) positive expression of CD56 marker; C) positive expression of CD57 marker; D) Ki-67 marker expression in 70% of tumor cells

Molecular analysis of translocations associated with Ewing sarcoma: case report

Leonardo R. Soares; Hugo A. Bayeh; Izabela Cristina Albuquerque; Marise A. R. Moreira; Miguel A. C. Coutinho; Debora F. Rodrigues; Paula O. C. Queiroz; Ruffo Freitas-JuniorJ. Bras. Patol. Med. Lab. 2019;55(2):218-229DOI: 10.5935/1676-2444.20190020 ABSTRACT We report the case of a 25-year-old female patient having a large lesion in the right breast. The core biopsy revealed a

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Evaluation of the clinical analysis service provided to an emergency department

Angela S. Higioka; Jéssica M. Martins; Flavia MartinelloJ. Bras. Patol. Med. Lab. 2019;55(1):4-18DOI: 10.5935/1676-2444.20190005 ABSTRACT INTRODUCTION: Time for releasing test results and critical value communication by the clinical laboratory are considered important determinants of patients’ length of stay in the Emergency Department (ED). As well as physician satisfaction, they are used as quality indicators of the

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Profile of women with cervical changes from a city in the northeast brazil

Profile of women with cervical changes from a city in the northeast brazil

Thamyres Fernanda M. Pedrosa; Sérgio D. Magalhães Filho; Adrya Lúcia PeresJ. Bras. Patol. Med. Lab. 2019;55(1):29-3DOI: 10.5935/1676-2444.20190004 ABSTRACT INTRODUCTION: In Brazil, cervical cancer is the fourth leading cause of cancer death. It reached 5,430 deaths in the year 2013, with estimated 16,370 new cases by 2018. Its occurrence has been associated with previous human papillomavirus (HPV)

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Histopathological profile of patients diagnosed with malignant tumors assisted in a hospital of reference of agreste pernambucano

Ana Kátia S. Teixeira; Juliana Lúcia A. VasconcelosJ. Bras. Patol. Med. Lab. 2019;55(1):75-84DOI: 10.5935/1676-2444.20190002 ABSTRACT Cancer is considered a public health problem and is commonly known because of its high mortality rate worldwide. The histopathological evaluation is a fundamental requirement to determine the nature of the lesion, thus it is considered the gold standard examination

Histopathological profile of patients diagnosed with malignant tumors assisted in a hospital of reference of agreste pernambucano Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Peritoneal washing in gynecological neoplasias

Marcos Paulo R. Sanches; Anderson Matsubara; Marco Aurélio A. Grande; Luiz M. CollaçoJ. Bras. Patol. Med. Lab. 2019;55(1):19-28DOI: 10.5935/1676-2444.20190010 ABSTRACT INTRODUCTION AND OBJECTIVE: Peritoneal washing cytology is part of pathological staging of adenocarcinomas of the endometrium and ovary. The objective of this study was to verify the prevalence of cytology positive for malignancy in patients diagnosed

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Comparative evaluation of the quality of papanicolaou staining at different intervals of fixation times using 96% ethyl alcohol

Comparative evaluation of the quality of papanicolaou staining at different intervals of fixation times using 96% ethyl alcohol

Shirley Borges S. Quintana; Fabiano L. Carvalho; Glória Regina F. Silva; Maria Beatriz T. Campos; Maria Conceição S. Maia; Mario Lucio C. Araújo Júnior; Marcel S. B. QuintanaJ. Bras. Patol. Med. Lab. 2019;55(1):38-48DOI: 10.5935/1676-2444.20190006 ABSTRACT INTRODUCTION: Fixation of cytological smears consists of immediate immersion in appropriate fixative, in order to preserve cellular morphological characteristics, it is

Comparative evaluation of the quality of papanicolaou staining at different intervals of fixation times using 96% ethyl alcohol Read More »

Reações CISH para detecção de DNA. Fotomicrografia de reação CISH para DNA A) fígado; B) baço; C) pulmão; D) cérebro; ampliação 40×. É possível observar o precipitado marrom no núcleo celular resultante da reação enzimática do DAB com a peroxidase do complexo anticorpo ligado ao híbrido formado entre a sequência-alvo e a sonda nas reações com a sonda positiva (direita) em comparação com as reações com a sonda negativa (esquerda)

Validation of chromogenic in situ hybridization reactions for detection of DNA and RNA in formalin-fixed and paraffin-embedded tissues

Rachel L. Monteiro; Daniela S. Damaceno; Lidia M. Kimura; Cinthya S. Cirqueira; Juliana M. Guerra; Leonardo José T. AraújoJ. Bras. Pathol. Med. Lab. 2019;55(1):49-58doi.org/10.5935/1676-2444.20190008 ABSTRACT INTRODUCTION: Chromogenic in situ hybridization (CISH) is used alternatively to the traditional immunohistochemical methods for the diagnosis of infectious diseases in formalin-fixed paraffin-embedded samples, since it presents high sensitivity and specificity. This type

Validation of chromogenic in situ hybridization reactions for detection of DNA and RNA in formalin-fixed and paraffin-embedded tissues Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Comparative analysis of the histopathological and epidemiological profile of ductal and lobular breast carcinomas diagnosed at the hospital de clínicas da universidade federal do paraná during the period 2008-2013

Heloisa Z. Rocha; Graciele C. M. Manica; Lucia de Noronha; Edneia A. S. Ramos; Giseli KlassenJ. Bras. Patol. Med. Lab. 2019;55(1):59-7410.5935/1676-2444.20190009 ABSTRACT   INTRODUCTION: Breast cancer is the second leading cause of cancer death among women worldwide, and epidemiological studies may help understanding its mechanisms.OBJECTIVE: To carry out a survey of the number of breast cancer cases

Comparative analysis of the histopathological and epidemiological profile of ductal and lobular breast carcinomas diagnosed at the hospital de clínicas da universidade federal do paraná during the period 2008-2013 Read More »

Fetal death: obstetric, placental and fetal necroscopic factors

Fetal death: obstetric, placental and fetal necroscopic factors

Laura M. Giraldi; Thiago Ricardo K. Corrêa; Fabiana Schuelter-Trevisol; Carlos Otávio GonçalvesJ. Bras. Patol. Med. Lab. 2019;55(1):85-98DOI: 10.5935/1676-2444.20190007 ABSTRACT INTRODUCTION: Fetal death is defined as the death of the product of conception, regardless of gestational age.OBJECTIVES: The objective of this study was to investigate the maternal (obstetrical and placental) risk factors and the necropsy findings associated with

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