Brazilian Journal of Pathology and Laboratory Medicine

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DGC representative area selected for convolutional neural network training with at least 70% of the image, containing DGC DGC: dyscohesive/diffuse gastric carcinoma.

Multi-categorical classification using deep learning applied to the diagnosis of gastric cancer

Article Type, Issue, Original Article, Vol 56, Issue 1 /

Jonas Kloeckner; Tatiana K. Sansonowicz; Áttila L. Rodrigues; Tatiana W. N. NunesJ. Bras. Patol. Med. Lab. 2020;56(1):1-8DOI: 10.5935/1676-2444.20200013 ABSTRACT INTRODUCTION: Pathologists currently face a substantial increase in workload and complexity of their diagnosis work on different types of cancer. This is due to the increased incidence and detection of neoplasms, associated with diagnostic subspecialization and the […]

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Underreporting of scientific knowledge: a theme for reflection

Progesterone and estradiol receptors and Ki-67 in the superficial and deep infiltrating endometriosis

Article Type, Issue, Original Article, Vol 56, Issue 1 /

Luiz F. Sampaio Neto; Maria Cecilia Ferro; Laura D. Garcia; Beatriz C. RibeiroJ. Bras. Patol. Med. Lab. 2020;56(1):1-6DOI: 10.5935/1676-2444.20200014 ABSTRACT INTRODUCTION: Endometriosis is a hormone-dependent disease characterized by ectopic presence of endometrial tissue responsive to ovarian steroids. Estrogen and progesterone are the main regulators of endometrial tissue, and the expression of receptors of these hormones in

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Underreporting of scientific knowledge: a theme for reflection

Ductal carcinoma in situ of the breast: correlation of architectural, cytological, IHC findings and recurrence analysis

Article Type, Issue, Original Article, Vol 56, Issue 1 /

Thiago Acrux; Daniel Athanazio; Débora Gaudêncio; Caroline RochaJ. Bras. Patol. Med. Lab. 2020;56(1):1-8DOI: 10.5935/1676-2444.20200018 ABSTRACT OBJECTIVE: This study evaluated the histopathological features of ductal carcinoma in situ (DCIS), including cytological grade, architectural pattern and immunohistochemistry (IHC) in pure DCIS and DCIS associated with invasive carcinoma of no special type (ICNST).METHODS: We evaluated a series of 232 cases of pure

Ductal carcinoma in situ of the breast: correlation of architectural, cytological, IHC findings and recurrence analysis Read More »

Underreporting of scientific knowledge: a theme for reflection

Performance analysis of commercial rapid tests for serum troponin detection

Article Type, Issue, Original Article, Vol 56, Issue 1 /

Raquel Ida Ferreira; Marcela R. Amaral; Maytê S. R. Brito; Matheus P. Pinto; Ana Carolina R. Maranhão; Lucas R. R. Costa; Rômulo C. Vaz de MeloJ. Bras. Patol. Med. Lab. 2020;56(1):1-5DOI: 10.5935/1676-2444.20200020 ABSTRACT INTRODUCTION: Rapid tests represent an important diagnostic tool, providing results in a short period of time and eliminating the use of large automated

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The value of fasting in the diagnosis of medium-chain acyl-CoA dehydrogenase deficiency

Article Type, Case Report, Issue, Vol 56, Issue 1 /

Carmen R. Vargas; Marion Deon; Angela Sitta; Daniella M. Coelho; Patricia D. Silva; Larissa Murussi; Laura V. Fleith; Luis Pablo Gravina; Carolina Crespo; Moacir Wajner; Maria Teresa V. SanseverinoJ. Bras. Patol. Med. Lab. 2020;56(1):1-6DOI: 10.5935/1676-2444.20200011 ABSTRACT Female patient carrier of medium-chain acyl-CoA dehydrogenase deficiency (MCADD) with recurrent clinical episodes of hypoglycemia and altered level of

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Mucoepidermoid carcinoma of the retromolar region: case report

Article Type, Case Report, Issue, Vol 56, Issue 1 /

Rani Iani C. Gonçalo; Afonso N. Dantas; Everton F. Morais; Roseana A. FreitasJ. Bras. Patol. Med. Lab. 2020;56(1):1-4DOI: 10.5935/1676-2444.20200015 ABSTRACT The present study aimed to report a case of mucoepidermoid carcinoma (MEC), focusing on its clinical-pathological characteristics. At intraoral clinical examination, a nodular lesion was observed in the right pterygomandibular raphe region, with three years

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Disseminated and cutaneous cryptococcosis by C. neoformans VNI in an immunocompetent patient

Article Type, Case Report, Issue, Vol 56, Issue 1 /

Fernanda Cristina A. Maranhão; Douglas L. H. Fonseca; Graciella S. A. Santos; Luisa Andrea V. Fonseca; Eduardo José L. Santos; Denise Maria W. SilvaJ. Bras. Patol. Med. Lab. 2020;56(1):1-4DOI: 10.5935/1676-2444.20200017 ABSTRACT Cryptococcosis is caused by yeasts of the Cryptococcus neoformans/C. gattii complex, presenting cutaneous, respiratory and disseminated forms. A 44-year-old immunocompetent male with facial lesion and latent

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Granular cell tumor in female neonate: a case report

Article Type, Case Report, Issue, Vol 56, Issue 1 /

Henrique M. Pasqual; Andreza Maldaner; Maiara Christine Macagnan; Rafaela A. Link; Nathalia B. Correa; Renata S. Borges; Vitor B. SantanaJ. Bras. Patol. Med. Lab. 2020;56(1):1-3DOI: 10.5935/1676-2444.20200019 ABSTRACT The granular cell tumor (GCT) is a neoplasm of connective tissue which rarely occurs in children. This case report aims to describe and discuss the presentation of this

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Evaluation of HLA-G immune checkpoint molecule in melanocytic lesions

Article Type, Brief Communication, Issue, Vol 56, Issue 1 /

Raylane P. Gomes; Gabriela Tayrine Caetano; Lucas Henrique F. Sampaio; Camila R. Silva; Maurício B. Costa; Maria Auxiliadora Cysneiro; Isabela Jubé WastowskiJ. Bras. Patol. Med. Lab. 2020;56(1):1-4DOI: 10.5935/1676-2444.20200016 ABSTRACT The human leukocyte antigen-G (HLA-G) is a non-classical molecule of the major histocompatibility complex. HLA-G has been associated with the process of tumorigenesis and tumor escape.

Evaluation of HLA-G immune checkpoint molecule in melanocytic lesions Read More »

Underreporting of scientific knowledge: a theme for reflection

The usefulness of high-risk HPV hybrid capture in patients with squamous cell atypia in cervical cytological examination

Article Type, Issue, Original Article, Vol 56, Issue 1 /

Flora A. Adorno; Daniele Cristina F. Lousada; Karina M. P. A. Coelho; Paulo Henrique C. FrançaJ. Bras. Patol. Med. Lab. 2020;56(1):1-6DOI: 10.5935/1676-2444.20200006 ABSTRACT INTRODUCTION: The cervical cytological examination and the investigation of high-risk human papillomavirus (HPV) deoxyribonucleic acid (DNA) are well-known valuable tools for screening of cervical lesions, since they allow the early diagnosis of cancer

The usefulness of high-risk HPV hybrid capture in patients with squamous cell atypia in cervical cytological examination Read More »