Brazilian Journal of Pathology and Laboratory Medicine

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Immunohistochemical reaction for IFN-γ (20× magnification); diffuse positivity in lesion cells Source: prepared by the author. IFN-γ: interferon-gamma.

Meningiomas and the tumor microenvironment: expression of pd-l1 and expression of pd-l1 and interferon-gamma in the prognosis

Gunter Gerson; Paulo G. B. Silva; Carlos Eduardo L. Soares; Gabriel C. L. Chagas; Amanda R. Rangel; Aline K. A. Rodrigues; Cleto D. Nogueira; Fábio R. F. TávoraJ. Bras. Patol. Med. Lab. 2020;56(1):1-8DOI: 10.5935/1676-2444.20200028 ABSTRACT INTRODUCTION: Meningiomas are the most common intracranial tumors in adults. One of the mechanisms used by tumor cells to escape death […]

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Underreporting of scientific knowledge: a theme for reflection

Incidence of Chlamydia trachomatis detected by pcr in women’s endocervical samples in Lages, Santa Catarina, Brazil

Rafael L. Miguel; Luiz Claudio Miletti; Bruna Fernanda da SilvaJ. Bras. Patol. Med. Lab. 2020;56(1):1-7DOI: 10.5935/1676-2444.20200029 ABSTRACT INTRODUCTION: Chlamydia trachomatis is one of the major causative agents of sexually transmitted infections (STI) in men and women, but the greatest impact of infection occurs in the reproductive system of women, causing, among other problems, infertility.OBJECTIVE: To estimate the incidence

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Underreporting of scientific knowledge: a theme for reflection

Nonconformities in the pre-analytical phase identified in a public health laboratory

Roberta Kelly L. Souza; Etienne W. Coan; Mauren I. AnghebemJ. Bras. Patol. Med. Lab. 2020;56(1):1-8DOI: 10.5935/1676-2444.20200027 ABSTRACT INTRODUCTION: The nonconformities detected in the pre-analytical phase of laboratory tests sent to the Central Public Health Laboratories (Lacen) culminate in the loss of epidemiological data of great importance for public health and are detrimental to health surveillance. This

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Clinical-pathological aspects of oral lymphoepithelial cyst: case report

Lourival C. O. N. Rocha; Gabriel G. Silva; Mariana C. Xerez; Caio César S. Barros; Juliana C. Pinheiro; Laudenice L. Pereira; Antônio L. L. CostaJ. Bras. Patol. Med. Lab. 2020;56(1):1-4DOI: 10.5935/1676-2444.20200026 ABSTRACT O cisto linfoepitelial oral (CLEO) é uma lesão incomum, cuja patogênese ainda é pouco elucidada. O objetivo deste estudo é relatar um caso

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Eosinophilic granuloma: an unusual finding in adults

Bruno F. B. B. Abreu; Marcio Luís Duarte; Murilo G. Grande; Newton M. Lima Neto; Edimeire F. OttoniJ. Bras. Patol. Med. Lab. 2020;56(1):1-4DOI: 10.5935/1676-2444.20200025 ABSTRACT A 45-year-old man presents with occipital headache for about one month, resistant to analgesic therapy, and palpable nodule at the pain site. At initial evaluation, the nodule was 1.5 cm

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Underreporting of scientific knowledge: a theme for reflection

Performance evaluation of HIV infection diagnostic tests

Márcia Jorge Castejon; Rosemeire Yamashiro; Carmem Aparecida F. Oliveira; Evelyn Helena A. Mata; Luís Fernando M. Brígido; Mark Drew C. Guimarães; Maria Amélia S. M. Veras3J. Bras. Patol. Med. Lab. 2020;56(1):1-7DOI: 10.5935/1676-2444.20200024 ABSTRACT INTRODUCTION: Many factors can impact the performance of diagnostic assays for the human immunodeficiency virus (HIV) infection, affecting the results of population surveys.OBJECTIVE: The

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First report of hemosiderotic adenodermatofibroma in Brazil

Miguel Augusto M. Pereira; Luciana Pantaleão; Mayra C. RochaelJ. Bras. Patol. Med. Lab. 2020;56(1):1-3DOI: 10.5935/1676-2444.20200023 ABSTRACT Hemosiderotic adenodermatofibroma is a recently recognized lesion, characterized by a dermal nodule with cystic structures of an apocrine gland, surrounded by a dermatofibroma-like stroma with hemosiderotic macrophages. We present the first case report of this entity in Brazil together

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Comparison of micronuclei frequency between smokers and non-smokers: a systematic review

Rodrigo B. Andrade; Nadine Alessandra CamposJ. Bras. Patol. Med. Lab. 2020;56(1):1-7DOI: 10.5935/1676-2444.20200022 ABSTRACT INTRODUCTION: Cancer results from the accumulation of several modifications in the genetic material and, therefore, it is possible to carry out its cytogenetic detection using biomarkers. Micronuclei (MN) have been addressed in the literature as biomarkers of genotoxic damage. These markers provide information

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Underreporting of scientific knowledge: a theme for reflection

Evaluation of PSA requests in men under 40 years of age

Fernando Antonio G. R. Araújo; Luana A. Bittencourt; Nairo M. Sumita; Ubirajara O. Barroso Jr.J. Bras. Patol. Med. Lab. 2020;56(1):1-5DOI: 10.5935/1676-2444.20200021 ABSTRACT OBJECTIVES: To evaluate the frequency of PSA requests in men under age 40 years; and to observe the possible influence of medical specialty of the requesting physician.MATERIAL AND METHOD: This is an observational, cross-sectional study

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Underreporting of scientific knowledge: a theme for reflection

Association of the CHGA gene polymorphism in patients with hemorrhagic stroke and/or aneurysm

Joanilson C. M. Santos Jr.; Caroline F. Fratelli; Alan Cristian F. Nóbrega; Suzana Cristina Rodrigues; Ligia Canongia A. C. Duarte; Calliandra Maria S. Silva; Jonathan D. Lima; Luzitano B. Ferreira; Daniel O. Freire; Vivian Taís F. Cipriano; Izabel Cristina R. Silva; Hélia Carla SouzaJ. Bras. Patol. Med. Lab. 2020;56(1):1-6DOI: 10.5935/1676-2444.20200012 ABSTRACT INTRODUCTION: Cerebrovascular diseases have been

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