Review Article – Brazilian Journal of Pathology and Laboratory Medicine

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Lung cancer biomarkers. A literature review

Biomarcadores de câncer de pulmão. Uma revisão de literatura Amanda Angelo Soares Costa1; Glaucia Luciano da Veiga2; Beatriz da Costa Aguiar Alves2; Thaís Moura Gascón2; Edimar Cristiano Pereira1; Ligia Ajaime Azzalis1; Fernando Luiz Affonso Fonseca1,2 1 Department of Pharmaceutical Sciences, Federal University of São Paulo/UNIFESP-Diadema, Brazil.2 Clinical Analysis Laboratory, ABC Faculty of Medicine, Santo André, […]

Lung cancer biomarkers. A literature review Read More »

CRISPR-Cas9 system: an alternative therapy for lung cancer

Article Type, Issue, Review Article, Vol 57, Issue 1 / admin

Sistema CRISPR-Cas9: uma alternativa terapêutica para neoplasia pulmonar Amanda S. R. Almeida; Cleide B. SouzaJ Bras Patol Med Lab. 2021; 57: 1-8.DOI: 10.5935/1676-2444.20210051 ABSTRACT Neoplasms are caused by mutations in deoxyribonucleic acid (DNA) characterized by debilitating treatments and difficult early diagnosis. In 2018, there were 27,200 deaths from lung cancer and 31,270 new cases of

CRISPR-Cas9 system: an alternative therapy for lung cancer Read More »

Underreporting of scientific knowledge: a theme for reflection

The importance of homocysteine levels in the prognosis of patients with chronic renal disease and in hemodialysis patients

Review Article / wadmin

Importância dos níveis de homocisteína no prognóstico de pacientes com doença renal crônica e em pacientes em hemodiálise Bruna M. Martella1; Glaucia Raquel L. Veiga1; Beatriz C. A. Alves1; Ligia A. Azzalis2; Virginia B. C. Junqueira2; Flavia S. Gehrkei3; Fernando Luiz A. Fonseca1, 2; Marcelo R. Bacci1 1. Faculdade de Medicina do ABC (FMABC), São

The importance of homocysteine levels in the prognosis of patients with chronic renal disease and in hemodialysis patients Read More »

The importance of flow cytometry in the diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria

Article Type, Issue, Review Article, Vol 57, Issue 1 / admin

Lethicia R. Ehlert; Camila L. Silva; Allyne Cristina GrandoJ. Bras. Patol. Med. Lab. 2021;57(1):1-8 ABSTRACT INTRODUCTION: The paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal disease of the hematopoietic stem cells, and it is clinically characterized by chronic intravascular hemolysis, bone marrow failure and hypercoagulability leading to thrombosis. It is a rare disorder of the hematopoietic

The importance of flow cytometry in the diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria Read More »

Interference of medicines in laboratory exams

Review Article / wadmin

Interferência dos medicamentos nos exames laboratoriais Raquel S. Silva; Caroline P. Domingueti; Marlon S. Tinoco; Júlio César Veloso; Mariana L. Pereira; André O. Baldoni; Danyelle R. A. Rios Universidade Federal de São João del-Rei (UFSJ), Divinópolis, Minas Gerais, Brazil DOi: 10.5935/1676-2444.20210014 Corresponding author Danyelle Romana Alves Rios0000-0001-6377-241Xe-mail: danyelleromana@ufsj.edu.br First Submission on 1/30/2020 Last Submission on 2/11/2020Accepted for

Interference of medicines in laboratory exams Read More »

Hereditary hemochromatosis associated with the development of liver cirrhosis

Review Article / wadmin

Hemocromatose hereditária associada ao desenvolvimento da cirrose hepática Taylla S. Costa; Jaqueline M. Ferreira; Marina F. Couto; Regina S. Nascimento Universidade Salvador, Salvador, Bahia, Brazil DOI: 10.5935/1676-2444.20210017 Corresponding author Taylla dos Santos Costa0000-0002-9192-0384e-mail: taylla.costa13@gmail.com First Submission on 3/11/2020 Last Submission on 3/15/2020Accepted for publication on 5/31/2020Published on 3/20/2021 ABSTRACT Hereditary hemochromatosis (HH) is an autosomal recessive disease, most often

Hereditary hemochromatosis associated with the development of liver cirrhosis Read More »

Flow cytometry as a diagnostic tool in childhood solid tumors

Article Type, Issue, Review Article, Vol 57, Issue 1 / wadmin

Gislaine Furlanetto; Fabiane Spagnol; Ana Paula Alegretti; Mariela G. Farias; Victor J. Soares; Liane E. Daudt; Jiseh F. Loss; Mariana B. MichalowskiJ. Bras. Patol. Med. Lab. 2021;57(1):1-9DOI: 10.5935/1676-2444.20210042 ABSTRACT Childhood solid tumors represent about 30% of all pediatric cancers. In recent years, there has been some expansion in the use of flow cytometry (FC) in

Flow cytometry as a diagnostic tool in childhood solid tumors Read More »

The influence of tobacco and alcohol in oral cancer: literature review

Review Article / wadmin

A influência da associação de tabaco e álcool no câncer bucal: revisão de literatura Rafaella B. Leite; Ana Carla O. Marinho; Beatriz L. Costa; Maria Beatriz V. Laranjeira; Kleyber D. T. Araújo; Anaícla F. M. Cavalcanti Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil DOI: 10.5935/1676-2444.20210001 Corresponding author Rafaella Bastos

The influence of tobacco and alcohol in oral cancer: literature review Read More »

Complications of idiopathic thrombocytopenic purpura in pregnancy: a review of literature

Review Article / wadmin

Complicações da púrpura trombocitopênica idiopática na gravidez: uma revisão da literatura Camila L. Silva; Allyne Cristina Grando Universidade Luterana do Brasil, Canoas, Rio Grande do Sul, Brazil. DOI: 10.5935/1676-2444.20210006 Corresponding author Camila Lima da SilvaORCID 0000-0002-8132-4546e-mail: camila.bio.95@gmail.com First Submission on 12/1/2019 Last Submission on 12/4/2019Accepted for publication on 1/10/2020Published on 1/15/2021 ABSTRACT INTRODUCTION: Idiopathic thrombocytopenic purpura (ITP) is an acquired

Complications of idiopathic thrombocytopenic purpura in pregnancy: a review of literature Read More »

The importance of flow cytometry in the diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria

Review Article / wadmin

A importância da citometria de fluxo no diagnóstico e monitoramento da hemoglobinúria paroxística noturna Lethicia R. Ehlert; Camila L. Silva; Allyne Cristina Grando Universidade Luterana do Brasil, Canoas, Rio Grande do Sul, Brazil DOI: 10.5935/1676-2444.20210019 Corresponding author Allyne Cristina Grando0000-0001-9384-0313e-mail: allynegrando@gmail.com First Submission on 4/3/2020 Last Submission on 4/5/2020Accepted for publication on 4/5/2020Published on 3/20/2021 ABSTRACT INTRODUCTION: The paroxysmal nocturnal

The importance of flow cytometry in the diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria Read More »