Brazilian Journal of Pathology and Laboratory Medicine

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Pathology

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Correlation and comparison of immunohistochemistry for HER2/neu, using the antibody SP3 and chromogenic in situ hybridization in breast carcinomas samples

Franciele F. Wolf; Giuliano S. Bublitz; Henrique R. FrigeriJ. Bras. Patol. Med. Lab. 2015;51(6):407-414DOI: 10.5935/1676-2444.20150063 ABSTRACT INTRODUCTION: Advances in the field of molecular biology have provided the differentiation of molecular subtypes of breast tumors, providing better prognosis and important tools for the treatment of patients with breast cancer. Among these subtypes, the changes in the human […]

Correlation and comparison of immunohistochemistry for HER2/neu, using the antibody SP3 and chromogenic in situ hybridization in breast carcinomas samples Read More »

Underreporting of scientific knowledge: a theme for reflection

Immunohistochemical study of macrophages subpopulations associated with squamous cell carcinoma of the tongue, with and without metastasis

Estudo imuno-histoquímico das subpopulações de macrófagos associados a tumores em carcinoma epidermoide de língua, com e sem metástase Natália G. Barbosa; Melka C. Sá; Leão P. Pinto; Roseana A. Freitas Universidade Federal do Rio Grande do Norte (UFRN) DOI: 10.5935/1676-2444.20150064 Corresponding author Roseana de Almeida FreitasUniversidade Federal do Rio Grande do Norte; Departamento de OdontologiaAvenida

Immunohistochemical study of macrophages subpopulations associated with squamous cell carcinoma of the tongue, with and without metastasis Read More »

SCC of the tongue Intense immunohistochemical expression of CD68 (A and B) and CD163 (C and D), showing compressive invasion pattern, with outlined infiltrating border adjacent to abundant inflammatory infiltrate (Panoramic Viewer, Advance). SCC: squamous cell carcinoma.

Immunohistochemical study of macrophages subpopulations associated with squamous cell carcinoma of the tongue, with and without metastasis

Natália G. Barbosa; Melka C. Sá; Leão P. Pinto; Roseana A. FreitasJ. Bras. Patol. Med. Lab. 2015;51(6):415-421DOI: 10.5935/1676-2444.20150064 ABSTRACT INTRODUCTION: Stromal cells interact with tumor cells and play an important role in cancer invasion and metastasis. Tumor-associated macrophages (TAMs) can exhibit M1 phenotype, important immune effector cells, or M2 phenotype, able to suppress the function of

Immunohistochemical study of macrophages subpopulations associated with squamous cell carcinoma of the tongue, with and without metastasis Read More »

Underreporting of scientific knowledge: a theme for reflection

Inflammatory myofibroblastic tumour arising incidentally as a polypoid lesion in the gallbladder

Tumor miofibroblástico inflamatório surgindo incidentalmente como lesão polipoide na vesícula biliar Carlos Filipe C. Abrantes1; Mário Rui Silva1; Rui Caetano Oliveira1; Catarina Eloy2; Maria Augusta Cipriano1; Lígia P. Castro1 1. Centro Hospitalar e Universitário de Coimbra2. Instituto de Patologia e Imunologia Molecular da Universidade do Porto (IPATIMUP) DOI: 10.5935/1676-2444.20150065 Corresponding author Carlos Filipe C. AbrantesCentro

Inflammatory myofibroblastic tumour arising incidentally as a polypoid lesion in the gallbladder Read More »

Gross and microscopic examination: pathological findings of inflammatory myofibroblastic tumour

Inflammatory myofibroblastic tumour arising incidentally as a polypoid lesion in the gallbladder

Carlos Filipe C. Abrantes; Mário Rui Silva; Rui Caetano Oliveira; Catarina Eloy; Maria Augusta Cipriano; Lígia P. CastroJ. Bras. Patol. Med. Lab. 2015;51(6):422-426DOI: 10.5935/1676-2444.20150065 ABSTRACT Inflammatory myofibroblastic tumour (IMT) is a rare mesenchymal neoplasm that usually originates from abdominal soft tissues. A female patient aged 50 years presented with a 1.2 cm gallbladder polyp. The

Inflammatory myofibroblastic tumour arising incidentally as a polypoid lesion in the gallbladder Read More »

Underreporting of scientific knowledge: a theme for reflection

Squamous odontogenic tumor: report of a case of unusual involvement

Tumor odontogênico escamoso: relato de um caso de envolvimento incomum Priscilla S. C. Lúcio1; Marcelo Augusto O. Sales2; Gustavo P. Godoy3; Rivadávio F. B. Amorim4 1. Universidade Estadual da Paraíba (UEPB)2. Universidade Federal da Paraíba (UFPB)3. Universidade Federal de Pernambuco (UFPE)4. Harvard Medical School DOI: 10.5935/1676-2444.20150066 Corresponding author Priscilla Suassuna Carneiro LúcioRua Desportista Aurélio Rocha,

Squamous odontogenic tumor: report of a case of unusual involvement Read More »

Axial, coronal, sagittal and 3D images Expansive hypodense lesion in the mandibular symphysis and parasymphysis

Squamous odontogenic tumor: report of a case of unusual involvement

Priscilla S. C. Lúcio; Marcelo Augusto O. Sales; Gustavo P. Godoy; Rivadávio F. B. AmorimJ. Bras. Patol. Med. Lab. 2015;51(6):427-431DOI: 10.5935/1676-2444.20150066 ABSTRACT The squamous odontogenic tumor (SOT) is defined as a very rare benign neoplasm, locally infiltrative and can extend to neighboring structures. This study aimed to report a case of SOT unusual involvement. A

Squamous odontogenic tumor: report of a case of unusual involvement Read More »

Metastasis of breast invasive ductal carcinoma in CNS parenchyma

Relationship between age and progesterone receptor expression with presence of central nervous system metastases in breast invasive ductal carcinoma

Eduardo Cambruzzi; Luana R. Gassen; Andrei Reginatto; Andressa Noshang; Fernanda P. Brandão; Larissa R. Roman; Luciana H. Miranda; Karla Lais PêgasJ. Bras. Patol. Med. Lab. 2015;51(5):323-328DOI:10.5935/1676-2444.20150052 ABSTRACT INTRODUCTION: Breast invasive carcinoma of no special type (NST) is characterized by great morphological heterogeneity, and accounts for about 70%-80% of malignant breast tumors. The main prognostic factors are

Relationship between age and progesterone receptor expression with presence of central nervous system metastases in breast invasive ductal carcinoma Read More »

Underreporting of scientific knowledge: a theme for reflection

Relationship between age and progesterone receptor expression with presence of central nervous system metastases in breast invasive ductal carcinoma

Relação entre idade e expressão do receptor de progesterona com presença de metástases no sistema nervoso central no carcinoma ductal invasivo da mama Eduardo Cambruzzi1; Luana R. Gassen2; Andrei Reginatto3; Andressa Noshang2; Fernanda P. Brandão2; Larissa R. Roman2; Luciana H. Miranda2; Karla Lais Pêgas3,4 1. Instituto de Cardiologia-Fundação Universitária de Cardiologia (IC-FUC)2. Universidade Luterana do

Relationship between age and progesterone receptor expression with presence of central nervous system metastases in breast invasive ductal carcinoma Read More »

Thyroid neoplasms at Inca between January 2001 and December 2012. HPD (n = 2,040)

Accuracy of intraoperative consultation in thyroid nodules: analysis of 2,040 cases performed at Instituto Nacional de Câncer in 12 years

Theresinha C. Fonseca; Ana Lúcia A. Eisenberg; Mário Lúcio C. Araújo Jr.J. Bras. Patol. Med. Lab. 2015;51(5):329-334DOI:10.5935/1676-2444.20150053 ABSTRACT INTRODUCTION: The thyroid nodule is the most common clinical manifestation of thyroid diseases, and, among the procedures for its diagnosis, cytological examination is the most used. Due to the high accuracy of cytological examination, the value of intraoperative

Accuracy of intraoperative consultation in thyroid nodules: analysis of 2,040 cases performed at Instituto Nacional de Câncer in 12 years Read More »