Brazilian Journal of Pathology and Laboratory Medicine

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Description of the quality indicators defined in the National Reference Laboratory in Tuberculosis of CRPHF/Ensp/Fiocruz by means of the process mapping methodology

Article Type, Issue, Original Article, Vol 53 issue 3 /

Aila Maronna; Renata A. Souza; Fatima Cristina O. F. MontesJ. Bras. Patol. Med. Lab. 2017;53(3):165-176DOI: 10.5935/1676-2444.20170028 ABSTRACT INTRODUCTION: The National Reference Laboratory (LRN) in Tuberculosis (TB) is a laboratory unit of highly specialized technical excellence that has developed projects involving training in human resources and the enhancement of techniques essential for the diagnosis of TB. Its […]

Description of the quality indicators defined in the National Reference Laboratory in Tuberculosis of CRPHF/Ensp/Fiocruz by means of the process mapping methodology Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Antimicrobial susceptibility of Streptococcus pneumoniae isolated from patients in the northeastern macroregion of São Paulo state, Brazil, 1998-2013

Article Type, Issue, Original Article, Vol 53 issue 3 /

Marta Inês C. Medeiros; Samanta Cristine G. Almeida; Sérgio Bokermann; Evandro Watanabe; Maria Luiza L. S. Guerra; Denise de AndradeJ. Bras. Patol. Med. Lab. 2017;53(3):177-182DOI: 10.5935/1676-2444.20170029 ABSTRACT INTRODUCTION: There are reports worldwide about the increase in infections caused by Streptococcus pneumoniae resistant to antimicrobials.OBJECTIVE: Evaluate the susceptibility profile of serotypes of Streptococcus pneumoniae associating them with pneumococcal invasive diseases (PID), as

Antimicrobial susceptibility of Streptococcus pneumoniae isolated from patients in the northeastern macroregion of São Paulo state, Brazil, 1998-2013 Read More »

No association between glutathione S-transferase M1 and T1 gene polymorphisms and susceptibility to endometriosis

Article Type, Issue, Original Article, Vol 53 issue 3 /

Letícia C. Batista; Mariangela T. Ruiz-Cintra; Marco Fábio P. Lima; Alessandra Bernadete Trovó de MarquiJ. Bras. Patol. Med. Lab. 2017;53(3):183-187DOI: 10.5935/1676-2444.20170024 ABSTRACT INTRODUCTION: Endometriosis is a common gynecologic disorder influenced by genetic and environmental factors. The glutathione S-transferase family is associated with endometriosis because its main function is cellular detoxification, so the absence of those enzymes

No association between glutathione S-transferase M1 and T1 gene polymorphisms and susceptibility to endometriosis Read More »

Study on the stability of HIV and syphilis reference materials under varied temperature conditions during their transportation

Article Type, Issue, Original Article, Vol 53 issue 3 /

Márcia J. Castejon; Rosemeire Yamashiro; Camila C. Oliveira; Elaine L. Oliveira; Edilene P. R. Silveira; Carmem Aparecida F. OliveiraJ. Bras. Patol. Med. Lab. 2017;53(3):188-195DOI: 10.5935/1676-2444.20170025 ABSTRACT INTRODUCTION: The objective of this study was to evaluate the short-term stability of the serum samples used as internal quality control (IQC) of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (Aids)

Study on the stability of HIV and syphilis reference materials under varied temperature conditions during their transportation Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Muscle biopsies in dermatomyositis and polymyositis: practical relevance of analyzing different levels of histological sections of the same muscular compartment

Article Type, Issue, Original Article, Vol 53 issue 3 /

Monica T. M. Diaz; Priscila S. Fraga; Marilda G. Silva; Samuel K. ShinjoJ. Bras. Patol. Med. Lab. 2017;53(3):196-201DOI: 10.5935/1676-2444.20170031 ABSTRACT INTRODUCTION: It is frequent in medical practice to have findings with normal aspects in histological muscle biopsies from patients with dermatomyositis (DM) or polymyositis (PM). This happens because, for example, the inflammatory infiltrate occurs in foci.OBJECTIVES: To

Muscle biopsies in dermatomyositis and polymyositis: practical relevance of analyzing different levels of histological sections of the same muscular compartment Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Blended learning strategies in teaching general pathology at a medical course

Article Type, Issue, Original Article, Vol 53 issue 3 /

Juliana A. Fermozelli; Mario Luis R. Cesaretti; Maria Lourdes P. BarboJ. Bras. Patol. Med. Lab. 2017;53(3):202-209DOI: 10.5935/1676-2444.20170032 ABSTRACT INTRODUCTION: In many medical schools, it is evident that learning of general pathology is deficient, mainly due to the disinterest in knowledge not directly related to professional practice and the lack of pedagogical resources that motivate learning. Blended

Blended learning strategies in teaching general pathology at a medical course Read More »

Underreporting of scientific knowledge: a theme for reflection

Creation of a comprehensive proficiency testing program for molecular diagnosis in Brazil

Article Type, Issue, Letter To Editor, Vol 53 issue 3 /

Gustavo B. Barra; Rafael H. Jácomo; Jéssica S. Gomes; Rafael M. LopesJ. Bras. Patol. Med. Lab. 2017;53(3):194-195DOI: 10.5935/1676-2444.20170030 External quality assessment (EQA) consists in the comparison of results from a laboratory with those from an external source – a group of laboratories or a reference laboratory. The implementation of a program of this nature helps

Creation of a comprehensive proficiency testing program for molecular diagnosis in Brazil Read More »

Giant nodular pseudoangiomatous stromal hyperplasia of the breast with fibroadenomatoid myxoid changes: a potential pitfall in the differential diagnosis of phyllodes tumor

Article Type, Case Report, Issue, Vol 53 issue 3 /

Roberto José Medeiros; Patricia Z. Rebutini; Thamyres G. V. Vargas; Fabiola Medeiros; Ana Paula M. SebastiãoJ. Bras. Patol. Med. Lab. 2017;53(3):210-214DOI: 10.5935/1676-2444.20170033 ABSTRACT A 21-year old woman presented with a 17-cm left breast mass. Physical examination and ultrasound revealed the mass to be well-circumscribed, homogeneous and freely mobile, suggestive of giant fibroadenoma or phyllodes tumor.

Giant nodular pseudoangiomatous stromal hyperplasia of the breast with fibroadenomatoid myxoid changes: a potential pitfall in the differential diagnosis of phyllodes tumor Read More »

Influence of obesity on the serum concentration of retinol-binding protein 4 (RBP4) in young adults

Article Type, Issue, Laboratory medicine, vol 53 issue 2 /

Eduardo O. Chielle; Aline Feltez; Eliandra M. RossiJ. Bras. Patol. Med. Lab. 2017;53(2):81-86DOI: 10.5935/1676-2444.20170012 ABSTRACT INTRODUCTION: Obesity is a chronic low-grade inflammation, in which macrophages play an important role in the maintenance of inflammation by producing pre-inflammatory and inflammatory substances such as retinol-binding protein 4 (RBP4), which acts as a trigger for adipose tissue inflammation and

Influence of obesity on the serum concentration of retinol-binding protein 4 (RBP4) in young adults Read More »