Brazilian Journal of Pathology and Laboratory Medicine

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Effectiveness of novel biomarkers of acute kidney injury in critically ill patients: a systematic review

Eficácia dos novos biomarcadores da injúria renal aguda em pacientes críticos:uma revisão sistemática Akeme Laissa N. Coutinho1; Djalma G. Xavier Filho1; Marcel Christian M. Tenório2; Matheus R. Lopes1; Adirlene P. O. Tenório1,2J Bras Patol Med Lab. 2021; 57: 1-10.DOI: 10.5935/1676-2444.20210059 ABSTRACT Introduction: Acute kidney injury (AKI) is defined as an abrupt decrease in the glomerular […]

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Underreporting of scientific knowledge: a theme for reflection

The importance of homocysteine levels in the prognosis of patients with chronic renal disease and in hemodialysis patients

Importância dos níveis de homocisteína no prognóstico de pacientes com doença renal crônica e em pacientes em hemodiálise Bruna M. Martella1; Glaucia Raquel L. Veiga1; Beatriz C. A. Alves1; Ligia A. Azzalis2; Virginia B. C. Junqueira2; Flavia S. Gehrkei3; Fernando Luiz A. Fonseca1, 2; Marcelo R. Bacci1 1. Faculdade de Medicina do ABC (FMABC), São

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Underreporting of scientific knowledge: a theme for reflection

Muscle biopsy with different levels of histological sections: an old procedure as a “still modern” approach

Acary S. B. OliveiraJ. Bras. Patol. Med. Lab. 2017;53(3):148-149DOI: 10.5935/1676-2444.20170026 The history of muscle biopsy dates back to 1860, when Duchenne first performed a biopsy on a patient with symptoms of myopathy(1). Since then, the basic and clinical science of muscle and muscle disease has gone through three stages of development: the classical period, the

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The importance of flow cytometry in the diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria

Lethicia R. Ehlert; Camila L. Silva; Allyne Cristina GrandoJ. Bras. Patol. Med. Lab. 2021;57(1):1-8 ABSTRACT INTRODUCTION: The paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal disease of the hematopoietic stem cells, and it is clinically characterized by chronic intravascular hemolysis, bone marrow failure and hypercoagulability leading to thrombosis. It is a rare disorder of the hematopoietic

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Hereditary hemochromatosis associated with the development of liver cirrhosis

Taylla S. Costa; Jaqueline M. Ferreira; Marina F. Couto; Regina S. NascimentoJ. Bras. Patol. Med. Lab. 2021;57(1):1-10 ABSTRACT Hereditary hemochromatosis (HH) is an autosomal recessive disease, most often associated with mutations in the HFE gene, which result in continuous absorption of iron, causing its overload. Liver tissue is the main site of iron deposition; thus, high levels

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Interference of medicines in laboratory exams

Raquel S. Silva; Caroline P. Domingueti; Marlon S. Tinoco; Júlio César Veloso; Mariana L. Pereira; André O. Baldoni; Danyelle R. A. RiosJ. Bras. Patol. Med. Lab. 2021;57(1):1-15 ABSTRACT OBJECTIVE: Conduct a survey on the interference of drugs in laboratory tests.METHODOLOGY: To identify the interference of each medication in laboratory tests, the Municipal List of Essential Medicines (Remume)

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Interference of medicines in laboratory exams

Raquel S. Silva; Caroline P. Domingueti; Marlon S. Tinoco; Júlio César Veloso; Mariana L. Pereira; André O. Baldoni; Danyelle R. A. RiosJ. Bras. Patol. Med. Lab. 2021;57(1):1-15 ABSTRACT OBJECTIVE: Conduct a survey on the interference of drugs in laboratory tests.METHODOLOGY: To identify the interference of each medication in laboratory tests, the Municipal List of Essential Medicines (Remume)

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Underreporting of scientific knowledge: a theme for reflection

Interference of medicines in laboratory exams

Interferência dos medicamentos nos exames laboratoriais Raquel S. Silva; Caroline P. Domingueti; Marlon S. Tinoco; Júlio César Veloso; Mariana L. Pereira; André O. Baldoni; Danyelle R. A. Rios Universidade Federal de São João del-Rei (UFSJ), Divinópolis, Minas Gerais, Brazil DOi: 10.5935/1676-2444.20210014 Corresponding author Danyelle Romana Alves Rios0000-0001-6377-241Xe-mail: danyelleromana@ufsj.edu.br First Submission on 1/30/2020 Last Submission on 2/11/2020Accepted for

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Underreporting of scientific knowledge: a theme for reflection

Hereditary hemochromatosis associated with the development of liver cirrhosis

Hemocromatose hereditária associada ao desenvolvimento da cirrose hepática Taylla S. Costa; Jaqueline M. Ferreira; Marina F. Couto; Regina S. Nascimento Universidade Salvador, Salvador, Bahia, Brazil DOI: 10.5935/1676-2444.20210017 Corresponding author Taylla dos Santos Costa0000-0002-9192-0384e-mail: taylla.costa13@gmail.com First Submission on 3/11/2020 Last Submission on 3/15/2020Accepted for publication on 5/31/2020Published on 3/20/2021 ABSTRACT Hereditary hemochromatosis (HH) is an autosomal recessive disease, most often

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Imagens obtidas do exame de ressonância magnética Sequências axial T2 (A), coronal T2 (B), axial T1 pós-contraste (C) e sagital T1 pós-contraste (D). Lesão meníngea retroclival com marcado hipossinal em T2 (setas em A e B); há compressão sobre o tronco cerebral, causando edema, com hipersinal em T2 (seta tracejada em A); nota-se realce intenso ao contraste nas sequências T1 pela lesão (setas em C e D).

Hypertrophic pachymeningitis, IgG4-related disease: case report

Paquimeningite hipertrófica, doença relacionada com a IgG4: relato de caso Gunter Gerson1; Carlos Eduardo L. Soares1; Amanda R. Rangel1; Gabriel C. L. Chagas1; Daniel R. F. Távora2; Kellen P. Fermon2 1. Universidade Federal do Ceará, Fortaleza, Ceará, Brasil2. Hospital Geral de Fortaleza, Fortaleza, Ceará, Brasil Corresponding author Gunter GersonORCID 0000-0001-9054-253Xe-mail: gunter_gerson@yahoo.com.br First Submission on 11/12/2019Last Submission on 11/12/2019Accepted

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