Brazilian Journal of Pathology and Laboratory Medicine

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Underreporting of scientific knowledge: a theme for reflection

False-negative result in molecular diagnosis of SARS-CoV-2 in samples with amplification inhibitors

Article Type, Issue, Original Article, Vol 56, Issue 1 /

Marcelo Fruehwirth; Açucena V. Rivas; Andressa F. R. Fitz; Aline Cristiane C. A. Batista; Cleypson Vinicius Silveira; Robson M. DelaiJ. Bras. Patol. Med. Lab. 2020;56(1):1-8DOI: 10.5935/1676-2444.20200060 ABSTRACT INTRODUCTION: Although reverse transcription-polymerase chain reaction (rRT-PCR) is the gold standard method for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), some factors, such as the presence of amplification […]

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Underreporting of scientific knowledge: a theme for reflection

False-negative result in molecular diagnosis of SARS-CoV-2 in samples with amplification inhibitors

Original Article /

Resultado falso negativo no diagnóstico molecular de SARS-CoV-2 em amostras com inibidores de amplificação Marcelo Fruehwirth; Açucena V. Rivas; Andressa F. R. Fitz; Aline Cristiane C. A. Batista; Cleypson Vinicius Silveira; Robson M. Delai Centro de Medicina Tropical da Tríplice Fronteira, Foz do Iguaçu, Paraná, Brazil DOI: 10.5935/1676-2444.20200060 Corresponding author Marcelo FruehwirthORCID 0000-0002-8548-3798e-mail: marcelo.fruehwirth@hmcc.com.br First Submission

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Coronavirus in a patient with hepatitis C: case report

Article Type, Case Report, Issue, Vol 56, Issue 1 /

Lucas R. Mostardeiro; Ellen Cristine A. Antoniolli; Jady W. XavierJ. Bras. Patol. Med. Lab. 2020;56(1):1-3DOI: 10.5935/1676-2444.20200059 ABSTRACT In February 2020, the World Health Organization (WHO) named the infection with the new coronavirus, which appeared in December 2019 in China, as COVID-19, and defined it as a worldwide pandemic. There is not much evidence about the

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Coronavirus in a patient with hepatitis C: case report

Case Report /

Coronavírus em paciente portador de hepatite C: relato de caso Lucas R. Mostardeiro1; Ellen Cristine A. Antoniolli2; Jady W. Xavier2 1. Universidade Católica de Pelotas, Pelotas, Rio Grande do Sul, Brazil2. Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil DOI: 10.5935/1676-2444.20200059 Corresponding author Lucas Rodrigues MostardeiroORCID 0000-0003-4232-3070e-mail: most-l@hotmail.com First Submission on

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Coronavirus in pediatrics: report of two cases and review of the literature

Case Report /

Lucas R. Mostardeiro; Ellen Cristine A. Antoniolli; Jady W. XavierJ. Bras. Patol. Med. Lab. 2020;56(1):1-4DOI: 10.5935/1676-2444.20200058 Coronavírus na pediatria: relato de dois casos e revisão da literatura Lucas R. Mostardeiro1; Ellen Cristine A. Antoniolli2; Jady W. Xavier2 1. Universidade Católica de Pelotas, Pelotas, Rio Grande do Sul, Brazil2. Hospital de Clínicas de Porto Alegre, Porto

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Coronavirus in pediatrics: report of two cases and review of the literature

Article Type, Case Report, Issue, Vol 56, Issue 1 /

Lucas R. Mostardeiro; Ellen Cristine A. Antoniolli; Jady W. XavierJ. Bras. Patol. Med. Lab. 2020;56(1):1-4DOI: 10.5935/1676-2444.20200058 ABSTRACT COVID-19 was identified on December 31, 2019 in China, and has since been the subject of several studies. In the area of pediatrics, the infection appears to affect this population group more mildly when compared to adults. The

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Coronavirus and the puerperium: a case report

Article Type, Case Report, Issue, Vol 56, Issue 1 /

Lucas R. Mostardeiro; Luiza G. Schmitt; Jady W. XavierJ. Bras. Patol. Med. Lab. 2020;56(1):1-4DOI: 10.5935/1676-2444.20200057 ABSTRACT COVID-19 started in China on December 31, 2019 and has since been the subject of several studies in medical field. There is not much evidence about the pregnancy and puerperium with the susceptibility of coronavirus infection (COVID-19). The present

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Underreporting of scientific knowledge: a theme for reflection

Immunopathological mechanisms involved in SARS-CoV-2 infection

Review Article /

Mecanismos imunopatológicos envolvidos na infecção por SARS-CoV-2 Sávio Breno P. Brito1; Isaque O. Braga1; Marília M. Moraes2; Carolina C. Cunha3; Sydney C. Leão1; Iukary Takenami1 1. Universidade Federal do Vale do São Francisco (UNIVASF), Paulo Afonso, Bahia, Brazil2. Escola Paulista de Medicina (UNIFESP), São Paulo, São Paulo, Brazil3. Instituto de Infectologia Emílio Ribas, São Paulo,

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Underreporting of scientific knowledge: a theme for reflection

Immunopathological mechanisms involved in SARS-CoV-2 infection

Article Type, Issue, Review Article, Vol 56, Issue 1 /

Sávio Breno P. Brito; Isaque O. Braga; Marília M. Moraes; Carolina C. Cunha; Sydney C. Leão; Iukary TakenamiJ. Bras. Patol. Med. Lab. 2020;56(1):1-10DOI: 10.5935/1676-2444.20200056 ABSTRACT INTRODUCTION: Coronavirus disease 2019 (Covid-19) has become a global health emergency. Although many scientific advances have been achieved over the last few months, the knowledge about how the etiologic agent SARS-CoV-2

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