Brazilian Journal of Pathology and Laboratory Medicine

Please contact: journal@jbpml.org.br

Original Article

CRISP3 glycoprotein: a good biomarker for prostate cancer?

Aparecida de Lourdes Carvalho; Sebastião A. Pinto; Wagner G. dos SantosJ. Bras. Patol. Med. Lab. 2021;57(1):1-7 ABSTRACT INTRODUCTION: Cysteine-rich secretory protein 3 (CRISP3) is expressed at low levels in normal human prostate but often overexpressed in prostate cancer (PCa). The relevance of this overexpression for the malignancy of PCa is still unclear. The prognostic value of […]

CRISP3 glycoprotein: a good biomarker for prostate cancer? Read More »

Impact of urinary selective antibiogram in primary care

Margarida Pereira; Gabriela Poças; Valquíria AlvesJ. Bras. Patol. Med. Lab. 2021;57(1):1-5 ABSTRACT INTRODUCTION: Selective reporting of antibiotic susceptibility test results (selective antibiogram), is increasingly recognized as one of the key strategies of antibiotic stewardship programs. The objective of this study is to determine the impact of selective susceptibility reporting on ciprofloxacin utilization and Escherichia coli susceptibility

Impact of urinary selective antibiogram in primary care Read More »

Bleach-concentrated direct sputum smear microscopy procedure for diagnosis of pulmonary tuberculosis in poverty areas

José L. O. Magalhães; Ana Albertina Araújo; Leonardo O. Silva; Ilyana O. Coutinho; Juliana F. C. Lima; Nilma C. Leal; Alzira M. P. AlmeidaJ. Bras. Patol. Med. Lab. 2021;57(1):1-8 ABSTRACT INTRODUCTION: Pulmonary tuberculosis caused by Mycobacterium tuberculosis is a serious public health problem affecting millions of people worldwide. The development of easy and low-cost diagnostic methods

Bleach-concentrated direct sputum smear microscopy procedure for diagnosis of pulmonary tuberculosis in poverty areas Read More »

HPV detection in oral mucosa samples in pediatric patients

Aline R. Gama; Marcos Antonio B. Carvalho Jr.; Isabela J. Wastowski; Stela O. Rodrigues; Maria Fernanda B. Souza; Lais S. Botacin; Melissa A. G. Avelino; Lilian Carla CarneiroJ. Bras. Patol. Med. Lab. 2021;57(1):1-5 ABSTRACT INTRODUCTION: The human papillomavirus (HPV) detection favors treatments for patients with clinical manifestations and limits future consequences for those with asymptomatic infections.OBJECTIVES: Therefore,

HPV detection in oral mucosa samples in pediatric patients Read More »

Umbilical cord constriction as a cause of intrauterine fetal death

Victor Antônio Kuiava; Henrique M. Pasqual; Ana Luiza S. Garcia; Bianca L. Barbarioli; Fernanda M. Carlotto; Gabriel K. Costa; Laurenlisiê L. H. Brittes; Maiara Christine Macagnan; Nathália Dal Prá Zucco; Rubens RodriguezJ. Bras. Patol. Med. Lab. 2021;57(1):1-5 ABSTRACT The umbilical cord constriction (UCC) is an uncommon condition and an important etiology for stillborn fetuses. The

Umbilical cord constriction as a cause of intrauterine fetal death Read More »

Pie charts showing percentages of patients with CTCs detected by analyses of the expression of TWIST-1, MGA and the combination of expression of both genes CTCs: circulating tumor cells.

The combination of mammaglobin A and TWIST-1 increases detection of circulating tumor cells in breast cancer

Georgina Gallucci; Estefanía Massa; Carlos C. Funes; Roberto Tozzini; Sergio Ghersevich J. Bras. Patol. Med. Lab. 2021;57(1):1-10 ABSTRACT OBJECTIVES: Breast cancer cells that are released into the bloodstream are called circulating tumor cells (CTCs). CTCs can express different genes, like TWIST-1 and mammaglobin A (MGA). The aims of this study were to analyze the expression of TWIST-1 and MGA in the blood

The combination of mammaglobin A and TWIST-1 increases detection of circulating tumor cells in breast cancer Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Relationship between serum concentrations of uric acid, insulin resistance and metabolic alterations in adolescents

Malene L. G. Sodré; Alice S. Ferreira; Andressa C. Ferreira; Anne Caroline S. Silva; Carla Milena A. Sá; Carlos Alberto D. Filho; Sally Cristina M. Monteiro J. Bras. Patol. Med. Lab. 2021;57(1):1-7DOI: 10.5935/1676-2444.20210020 ABSTRACT OBJECTIVE: To verify the possible relationship between serum uric acid concentrations and insulin resistance in adolescents.METHODS: This is a cross-sectional study with 74

Relationship between serum concentrations of uric acid, insulin resistance and metabolic alterations in adolescents Read More »

Fotomicrografias de imunomarcação para TIMP-1 em CCE

Analysis of TIMP-1 expression in leukoplakia and oral squamous cell carcinoma

Susy Carmelita P. Nascimento; Letícia N. G. Souza; Liliana Aparecida P. Barros J. Bras. Patol. Med. Lab. 2021;57(1):1-11 ABSTRACT INTRODUCTION: The current study about transition of oral epithelial dysplasia, present in lesions such as leukoplakia, for squamous cell carcinoma (SCC) involves not only the histopathological aspects, but also the analysis of the presence of biomarkers which

Analysis of TIMP-1 expression in leukoplakia and oral squamous cell carcinoma Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Follow-up of squamous atypia’s and the evaluation of the conducts according to the recommendations of the Ministry of Health

Mateus F. Delabeneta; Dayane B. Costa; Jacqueline Plewka; Maiara Aline Santos; Maurício TurkiewiczJ. Bras. Patol. Med. Lab. 2021;57(1):1-7DOI: 10.5935/1676-2444.20210028 ABSTRACT INTRODUCTION: Cervical cancer is considered a public health problem, ranking fourth among the most common types of cancer worldwide.OBJECTIVE: The present study aimed to gather information on the follow-up, and to verify adherence to the management recommended

Follow-up of squamous atypia’s and the evaluation of the conducts according to the recommendations of the Ministry of Health Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Impact of pre-analytical errors on costs of clinical analysis laboratory

Priscila R. Santos; Camila L. Silva; Magda C. Gall; Allyne Cristina GrandoJ. Bras. Patol. Med. Lab. 2021;57(1):1-5DOI: 10.5935/1676-2444.20210023 ABSTRACT INTRODUCTION: Currently, it is well known that quality assurance systems in healthcare organizations are constantly evolving. Quality improvements can reduce costs by avoiding repetition of exams, which results in a waste of time and money for the

Impact of pre-analytical errors on costs of clinical analysis laboratory Read More »