Laboratory Medicine – Page 8 – Brazilian Journal of Pathology and Laboratory Medicine

Underreporting of scientific knowledge: a theme for reflection

Haplotypes βs-globin and its clinical-haematological correlation in patients with sickle-cell anemia in Triângulo Mineiro, Minas Gerais, Brazil

Haplótipos da βs-globina e sua correlação clínica-hematológica em portadores de anemia falciforme no Triângulo Mineiro, Minas Gerais, Brasil Alexandra S. Leal1; Paulo Roberto J. Martins1,2; Marly Aparecida S. Balarin1; Gilberto A. Pereira1; Gláucia Aparecida D. Resende1 1. Universidade Federal do Triângulo Mineiro (UFTM), Minas Gerais, Brasil2. Fundação Hemominas, Minas Gerais, Brasil DOI: 10.5935/1676-2444.20160001 Corresponding author […]

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epresentation of average HbF level in genotypes F: fetal; HbF-M: mean fetal hemoglobin; ATP: atypical; BEN: Benin; CAR: Central African Republic; p < 0.05.

Haplotypes βs-globin and its clinical-haematological correlation in patients with sickle-cell anemia in Triângulo Mineiro, Minas Gerais, Brazil

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 1 / cadmin

Alexandra S. Leal; Paulo Roberto J. Martins; Marly Aparecida S. Balarin; Gilberto A. Pereira; Gláucia Aparecida D. ResendeJ. Bras. Patol. Med. Lab. 2016;52(1):5-10DOI: 10.5935/1676-2444.20160001 ABSTRACT INTRODUCTION: Sickle-cell anemia (SCA) is the most severe form of sickle-cell disease, and is characterized by homozygous hemoglobin S (α2βS2).OBJECTIVE: Determine the haplotypes frequency in patients with SCA and their correlation with

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Analysis of the frequency of biological sample recollections as quality indicators in a clinical laboratory of Distrito Federal, Brazil

Laboratory Medicine / cadmin

Análise da frequência de recoletas de amostras biológicas como indicadores de qualidade em um laboratório de análises clínicas do Distrito Federal, Brasil Natani L. Coriolano; Izabel Cristina R. Silva; Thaís A. C. Lamounier Faculdade de Ceilândia (FCE), Universidade de Brasília (UnB), Brasília, Brasil DOI: 10.5935/1676-2444.20160002 Corresponding author Thaís A. C. LamounierUniversidade de Brasília; Hospital UniversitárioCentro

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Analysis of the frequency of biological sample recollections as quality indicators in a clinical laboratory of Distrito Federal, Brazil

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 1 / cadmin

Natani L. Coriolano; Izabel Cristina R. Silva; Thaís A. C. LamounierJ. Bras. Patol. Med. Lab. 2016;52(1):11-16DOI: 10.5935/1676-2444.20160002 ABSTRACT INTRODUCTION: Clinical laboratory results influence more than 60% of medical decisions, impacting on disease prevention, diagnosis, and treatment. The use of quality indicators (QIs) is fundamental for quality assurance, once it allows monitoring the process and directs the

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The critical value concept in clinical laboratory

Laboratory Medicine / cadmin

O conceito de valores críticos no laboratório clínico Bruna Cláudia B. Rocha; José Adilson R. Alves; Félix Pedro D. Pinto; Maria Elizabete Mendes; Nairo M. Sumita Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP), São Paulo, Brasil DOI: 10.5935/1676-2444.20160008 Corresponding author Bruna da RochaAv. Dr. Eneas de Carvalho Aguiar, 155;

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The critical value concept in clinical laboratory

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 1 / cadmin

Bruna Cláudia B. Rocha; José Adilson R. Alves; Félix Pedro D. Pinto; Maria Elizabete Mendes; Nairo M. SumitaJ. Bras. Patol. Med. Lab. 2016;52(1):17-20DOI: 10.5935/1676-2444.20160008 ABSTRACT The critical value is a laboratory result representing a pathophysiological state that offers risk to a patient’s life. The communication of these results is a laboratory responsibility and, according to

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Allele frequencies for C282Y and H63D mutations

Prevalence of C282Y and H63D mutations in the HFE gene in patients from São Paulo and Southern Brazil

Article Type, Issue, Laboratory Medicine, Vol 52, Issue 1 / cadmin

Marcos E. Herkenhoff; Ana Kelly Pitlovanciv; Vanessa R. RemualdoJ. Bras. Patol. Med. Lab. 2016;52(1):21-24DOI: 10.5935/1676-2444.20160003 ABSTRACT Hereditary hemochromatosis (HH) is an autosomal recessive disorder caused by mutations in the HFE gene; it is characterized by the risk of iron overload. C282Y and H63D are the most associated mutations in HH. This study aimed to determine the frequency

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Prevalence of C282Y and H63D mutations in the HFE gene in patients from São Paulo and Southern Brazil

Laboratory Medicine / cadmin

Prevalência das mutações C282Y e H63D no gene HFE em pacientes de São Paulo e do Sul do Brasil Marcos E. Herkenhoff1; Ana Kelly Pitlovanciv2; Vanessa R. Remualdo2 1. Universidade Estadual Paulista (Unesp), São Paulo, Brasil2. Genolab, Santa Catarina, Brasil DOI: 10.5935/1676-2444.20160003 Corresponding author Marcos Edgar HerkenhoffLaboratório GenolabRua Marechal Floriano Peixoto, 425; CentroCEP: 89010-325; Blumenau-SC, Brasile-mail: marcos.herkenhoff@gmail.com First

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Comparison between immunofixation and electrophoresis for the early detection of relapsed multiple myeloma

Laboratory Medicine / wadmin

Comparação entre imunofixação e eletroforese na detecção precoce de recidivas do mieloma múltiplo Marta Helena C. Aita; Luiz Claudio Arantes; Bruno C. Aita; José Edson P. Silva Universidade Federal de Santa Maria (UFSM) DOI: 10.5935/1676-2444.20150057 Corresponding author Marta Helena Carlesso AitaEstrada Padre Gabriel Bolzan, 1.777, casa 71; São José, km 3CEP: 97095-500; Santa Maria-RS, Brazile-mail: marta.hc.aita@gmail.com

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Comparison between immunofixation and electrophoresis for the early detection of relapsed multiple myeloma

Article Type, Issue, Laboratory Medicine, Vol 51, Issue 6 / wadmin

Marta Helena C. Aita; Luiz Claudio Arantes; Bruno C. Aita; José Edson P. SilvaJ. Bras. Patol. Med. Lab. 2015;51(6):359-368DOI: 10.5935/1676-2444.20150057 ABSTRACT INTRODUCTION: Multiple myeloma (MM) is an incurable progressive hematological neoplasia characterized by heterogeneous evolution and by relapses after therapy.OBJECTIVE: Compare the effectiveness of serum immunofixation (SIF) and electrophoresis (SPE) techniques in the detection of relapses in

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