Brazilian Journal of Pathology and Laboratory Medicine

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Editorial

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Is muscle biopsy still necessary for the diagnosis of mitochondrial disease?

Paulo Victor S. Souza; Wladimir B. V. R. Pinto; Acary S. B. OliveiraJ. Bras. Patol. Med. Lab. 2018;54(5):272DOI:10.5935/1676-2444.20180046 ABSTRACT Mitochondria are essential organelles for human life and play a central role in diverse cellular processes such as energy production, reactive oxygen species, biosynthetic intermediates, autophagy, amino acid and fatty acid synthesis and degradation, heme synthesis, […]

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Underreporting of scientific knowledge: a theme for reflection

Is muscle biopsy still necessary for the diagnosis of mitochondrial disease?

Paulo Victor S. Souza; Wladimir B. V. R. Pinto; Acary S. B. Oliveira Universidade Federal de São Paulo (Unifesp), São Paulo, Brazil Mitochondria are essential organelles for human life and play a central role in diverse cellular processes such as energy production, reactive oxygen species, biosynthetic intermediates, autophagy, amino acid and fatty acid synthesis and

Is muscle biopsy still necessary for the diagnosis of mitochondrial disease? Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Transference of CALIPER total alkaline phosphatase reference interval to a Brazilian pediatric population

Natasha Slhessarenko; Adagmar AndrioloJ. Bras. Patol. Med. Lab. 2018;54(4):204-205DOI:10.5935/1676-2444.20180035 ABSTRACT The reference intervals (RI) represent a set of values used to interpret the results of quantitative laboratory tests and are powerful tools that assist health professionals in making decisions during patient care(1). The determination of their own RI gives diagnostic power, but it is one

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Underreporting of scientific knowledge: a theme for reflection

Transference of CALIPER total alkaline phosphatase reference interval to a Brazilian pediatric population

Natasha Slhessarenko1,2; Adagmar Andriolo3 1. Faculdade de Medicina da Universidade Federal de Mato Grosso (UFMT), Mato Grosso, Brazil2. Diagnósticos da América S.A. (DASA), Mato Grosso, Brazil3. Escola Paulista de Medicina da Universidade Federal de São Paulo (UNIFESP), São Paulo, Brazil The reference intervals (RI) represent a set of values used to interpret the results of

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Harmonization efforts add value to clinical laboratory and improve patient safety

Maria Elizabete MendesJ. Bras. Patol. Med. Lab. 2018;54(3):130-131DOI:10.5935/1676-2444.20180034   ABSTRACT Divisão de Laboratório Central do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (DLC-HCFMUSP), São Paulo, Brazil Laboratory tests provide a basis for medical decisions; for this reason they are of great relevance to healthcare, both in clarifying diagnoses, in prescribing

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Standards for the diagnosis and treatment of chronic myeloid leukemia

Paulo CampregherJ. Bras. Patol. Med. Lab. 2018;54(2):68DOI:10.5935/1676-2444.20180023 ABSTRACT Myeloproliferative disorders are a group of clonal myeloid neoplasms characterized by increased proliferation of myeloid cells with preserved cell differentiation. The molecular features of myeloproliferative neoplasms have been efficiently mapped in the last decades(1). Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm defined by the presence of

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Standards for the diagnosis and treatment of chronic myeloid leukemia

Paulo Campregher Laboratório de Genética Molecular do Hospital Israelita Albert Einstein, São Paulo, Brazil Myeloproliferative disorders are a group of clonal myeloid neoplasms characterized by increased proliferation of myeloid cells with preserved cell differentiation. The molecular features of myeloproliferative neoplasms have been efficiently mapped in the last decades(1). Chronic myeloid leukemia (CML) is a myeloproliferative

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

The paradigm for cardiovascular effects of hormonal contraceptives

English PDFPortuguese PDFFull text Zsuzsanna Ilona Katalin de Jármy Di BellaJ. Bras. Patol. Med. Lab. 2018;54(1):4DOI:10.5935/1676-2444.20180004 ABSTRACT Hormonal contraceptives revolutionized the world in the 1960s, allowing women to separate sexual intercourse from procreation. However, since then, doubts exist over the long-term negative side-effects of hormonal contraceptives. Arterial thromboembolic phenomena were soon associated with the estrogen

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

The paradigm for cardiovascular effects of hormonal contraceptives

Zsuzsanna Ilona Katalin de Jármy Di Bella Escola Paulista de Medicina/Universidade Federal de São Paulo (EPM/UNIFESP), São Paulo, Brazil Publicado em 27/03/2018 Hormonal contraceptives revolutionized the world in the 1960s, allowing women to separate sexual intercourse from procreation. However, since then, doubts exist over the long-term negative side-effects of hormonal contraceptives. Arterial thromboembolic phenomena were soon

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Underreporting of scientific knowledge: a theme for reflection

An overview of Acinetobacter baumannii: deciphering this amazing pathogen

Rodrigo CayôJ. Bras. Patol. Med. Lab. 2017;53(6):356-357DOI: 10.5935/1676-2444.20170056 Rodrigo Cayô Escola Paulista de Medicina/Universidade Federal de São Paulo (EPM/UNIFESP), São Paulo, Brazil The genus Acinetobacter comprises several groups of closely related species(1, 2), including the Acinetobacter calcoaceticus-baumannii complex that was initially proposed in 1991(3). At that time, it had not yet been described what would become one of the

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