Brazilian Journal of Pathology and Laboratory Medicine

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Case Report

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Investigation of chagas disease within the same family: case study

Nayore Tamie Takamiya; Erika Alessandra P. N. Costa; Simone B. Lucheis; Rodrigo M. Santos Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Faculdade de Medicina de Botucatu, Botucatu, São Paulo, Brazil DOI:10.5935/1676-2444.20190062 Corresponding author Nayore Tamie TakamiyaORCID 0000-0002-1831-1638e-mail: nayoretk@gmail.com First Submission on 3/18/2019Last Submission on 3/19/2019Accepted for publication on 5/8/2019Published on 12/20/2019 ABSTRACT Chagas disease (CD) is a neglected endemic […]

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Clinical difference between identical twins with sickle cell anemia

Marilia R. Laurentino; Tarcisio Paulo Almeida Filho; Pedro A. Maia Filho; Francisco O. F. Nascimento; Adlene F. Advincula; Clarissa Maria G. Machado; Romelia P. G. LemesJ. Bras. Patol. Med. Lab. 2019;55(6):703-708DOI:10.5935/1676-2444.20190063 ABSTRACT Sickle cell anemia (SCA) is a genetic disease that causes important clinical manifestations due to chronic hemolysis and vascular occlusion. The aim of

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Underreporting of scientific knowledge: a theme for reflection

Clinical difference between identical twins with sickle cell anemia

Diferenças clínicas entre gêmeas idênticas com anemia falciforme Clinical difference between identical twins with sickle cell anemia Diferenças clínicas entre gêmeas idênticas com anemia falciforme Marilia R. Laurentino1; Tarcisio Paulo Almeida Filho1; Pedro A. Maia Filho1; Francisco O. F. Nascimento2; Adlene F. Advincula2; Clarissa Maria G. Machado3; Romelia P. G. Lemes1 1. Universidade Federal do

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Clinical aspect Intraoral aspect of the patient, evidencing a purplish increased volume, located in the gingival region of the maxilla, in the area adjacent to the apex of the element 12.

Adenoid cystic carcinoma: immunohistochemistry and differential diagnosis, a case report

Mara Luana B. Severo; Caio César S. Barros; Lourival C. O. N. Rocha; Lucemário S. Macêdo; Márcia Cristina C. Miguel; Éricka Janine D. SilveiraJ. Bras. Patol. Med. Lab. 2019;55(5):540-549DOI: 10.5935/1676-2444.20190044 ABSTRACT A 52-year-old male patient complained of loss of sensitivity and pain in the maxilla. After examination, root canal treatment of tooth 12 was requested.

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Underreporting of scientific knowledge: a theme for reflection

Adenoid cystic carcinoma: immunohistochemistry and differential diagnosis, a case report

Carcinoma adenoide cístico: imuno-histoquímica e diagnóstico diferencial, um relato de caso Mara Luana B. Severo; Caio César S. Barros; Lourival C. O. N. Rocha; Lucemário S. Macêdo; Márcia Cristina C. Miguel; Éricka Janine D. Silveira Universidade Federal do Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte, Brazil Corresponding author Caio César da Silva

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he microscopic analysis showed intense well-differentiated squamous epithelial proliferation, with frequent invaginations (A, 5×). The fibrovascular stroma showed numerous inflammatory cells (B, 5×). Notice the large area of keratin deposition (asterisk), foci of osseous resorption in close relationship with florid squamous epithelial proliferation with prominent invagination (C, 5× and D, 20×). Hematoxylin and eosin stain

Gingival carcinoma cuniculatum mimicking a reactive/inflammatory process

Rodrigo N. Silva, Heitor A. Silveira, Luciana Y. Almeida, Carla N. B. Colturato, Alexandre Elias Trivellato, Cassio E. Sverzut, Jorge E. LeónJ. Bras. Patol. Med. Lab. 2019;55(5):498-505DOI: 10.5935/1676-2444.20190045 ABSTRACT Carcinoma cuniculatum (CC), a rare variant of oral squamous cell carcinoma, presents well-differentiated neoplastic epithelial cells infiltrating the underlying submucosal or bone tissues, forming the so-called

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Underreporting of scientific knowledge: a theme for reflection

Gingival carcinoma cuniculatum mimicking a reactive/inflammatory process

Carcinoma cuniculado gengival mimetizando um processo inflamatório/reativo Rodrigo N. Silva, Heitor A. Silveira, Luciana Y. Almeida, Carla N. B. Colturato, Alexandre Elias Trivellato, Cassio E. Sverzut, Jorge E. León 1. Universidade de São Paulo (USP), Ribeirão Preto, São Paulo, Brasil2. Universidade do Estado de São Paulo (UNESP), Araraquara, São Paulo, Brasil Corresponding author Jorge Esquiche

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Extraoral and intraoral clinical features of patient case 2 A) patient with short stature and stunted extremities; B) shortened phalanges; C) biprotrusion, bilateral posterior open bite, enamel hypoplasia, dental agenesis and rotated premolar.

Update of dental and maxillofacial alterations in patients with pycnodysostosis

Luiz Carlos Moreira Jr., Glória Maria França, Victor Diniz B. Santos, Hébel C. Galvão, Petrus P. Gomes, Adriano R. GermanoJ. Bras. Patol. Med. Lab. 2019;55(5):506-515DOI: 10.5935/1676-2444.20190046 ABSTRACT Pycnodysostosis is a rare, autosomal recessive genetic condition, which causes a decrease in bone remodeling, resulting in different clinical and radiographic manifestations. This case series aims to describe

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Underreporting of scientific knowledge: a theme for reflection

Update of dental and maxillofacial alterations in patients with pycnodysostosis

Atualização das alterações dentárias e dos ossos gnáticos em pacientes com picnodisostose Luiz Carlos Moreira Jr., Glória Maria França, Victor Diniz B. Santos, Hébel C. Galvão, Petrus P. Gomes, Adriano R. Germano Universidade Federal do Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte, Brazil DOI: 10.5935/1676-2444.20190046 Corresponding author Adriano R. Germano0000-0002-1661-8038e-mail: adrianorgermano@yahoo.com.br First Submission

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Lesion in dermoscopy

Dermatoscopy in polypoid basal-cell carcinoma: a rare histopathological variation

Mariana A. Almeida, Gabriella C. Carmo, Michele R. Feroldi, Gustavo VerardinoJ. Bras. Patol. Med. Lab. 2019;55(5):516-521DOI: 10.5935/1676-2444.20190047 ABSTRACT Polypoid basal-cell carcinoma (BCC) is a rare tumor, considered a clinical and histopathological variant of the nodular BCC, presenting broad exophytic or pedunculated base that connects to the surface of the skin and histopathologically displays the neoplastic

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