Brazilian Journal of Pathology and Laboratory Medicine

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Underreporting of scientific knowledge: a theme for reflection

Frequency of classes I and II HLA alleles in deceased donors of solid organs in Espírito Santo, Brazil

Frequência alélica HLA de classes I e II em doadores falecidos de órgãos sólidos no Espírito Santo, Brasil Fabiana Regina Barbosa1; Karla O. Freitas1; Rafaela C. Silva1; Sarah P. C. Pires1; Rodrigo Pratte-Santos1, 2 1. Faculdade PIO XII, Espírito Santo, Brazil2. Universidade Federal do Espírito Santo (UFES), Espírito Santo, Brazil Corresponding author Rodrigo Pratte-SantosAvenida Afonso […]

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Underreporting of scientific knowledge: a theme for reflection

JBPML puts its commitment to the care of safety in the laboratory

Silvana Maria Eloi-Santos Jornal Brasileiro de Patologia e Medicina Laboratorial (JBPML); Universidade Federal de Minas Gerais (UFMG) DOI: 10.5935/1676-2444.20150056 In 2009, the US Food and Drug Administration (FDA) approved the Clinical and Laboratory Standards Institute ([CLSI] – formerly NCCLS) consensus standard for auto verification of clinical laboratory test results(1). That guideline provides a general framework

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

JBPML puts its commitment to the care of safety in the laboratory

Silvana Maria Eloi-SantosJ. Bras. Patol. Med. Lab. 2015;51(6):358DOI: 10.5935/1676-2444.20150056 ABSTRACT In 2009, the US Food and Drug Administration (FDA) approved the Clinical and Laboratory Standards Institute ([CLSI] – formerly NCCLS) consensus standard for auto verification of clinical laboratory test results(1). That guideline provides a general framework that allows clinical laboratories to propose, implement, validate, and

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Comparison between immunofixation and electrophoresis for the early detection of relapsed multiple myeloma

Marta Helena C. Aita; Luiz Claudio Arantes; Bruno C. Aita; José Edson P. SilvaJ. Bras. Patol. Med. Lab. 2015;51(6):359-368DOI: 10.5935/1676-2444.20150057 ABSTRACT INTRODUCTION: Multiple myeloma (MM) is an incurable progressive hematological neoplasia characterized by heterogeneous evolution and by relapses after therapy.OBJECTIVE: Compare the effectiveness of serum immunofixation (SIF) and electrophoresis (SPE) techniques in the detection of relapses in

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Underreporting of scientific knowledge: a theme for reflection

Comparison between immunofixation and electrophoresis for the early detection of relapsed multiple myeloma

Comparação entre imunofixação e eletroforese na detecção precoce de recidivas do mieloma múltiplo Marta Helena C. Aita; Luiz Claudio Arantes; Bruno C. Aita; José Edson P. Silva Universidade Federal de Santa Maria (UFSM) DOI: 10.5935/1676-2444.20150057 Corresponding author Marta Helena Carlesso AitaEstrada Padre Gabriel Bolzan, 1.777, casa 71; São José, km 3CEP: 97095-500; Santa Maria-RS, Brazile-mail: marta.hc.aita@gmail.com

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Autoverification of the automated blood cell counter (CBC) in a reference laboratory in Bogota, Colombia

Oscar Martinez-Nieto; Adriana Lozano-Gaitán; Paola Beltrán-Diaz; Ivan Leonardo Mojica-Figueroa; Olga Lucia Morales-Reyes; Mario A. Isaza-RugetJ. Bras. Patol. Med. Lab. 2015;51(6):369-375DOI: 10.5935/1676-2444.20150058 ABSTRACT INTRODUCTION: The clinical laboratory is part of the group of actors in health systems that are under increasing pressure by users and administrators to increase their productivity in order to respond efficiently to the

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Underreporting of scientific knowledge: a theme for reflection

Autoverification of the automated blood cell counter (CBC) in a reference laboratory in Bogota, Colombia

Autoverificação do contador de células automatizado de sangue (CBC) em um laboratório de referência em Bogotá, Colômbia Oscar Martinez-Nieto1; Adriana Lozano-Gaitán1; Paola Beltrán-Diaz1; Ivan Leonardo Mojica-Figueroa1; Olga Lucia Morales-Reyes1; Mario A. Isaza-Ruget2 1. Clínica Colsanitas S.A., Bogotá, Colômbia2. Organización Sanitas S.A., Bogotá, Colômbia DOI: 10.5935/1676-2444.20150058 Corresponding author Oscar Martínez-NietoRua Carrera 69 C, 99-45Bogotá DC, Colombia;

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Cerebrospinal fluid biomarkers for the differential diagnosis of Alzheimer’s disease

Carolina A. Magalhães; Micheli Figueiró; Vanessa G. Fraga; Elvis C. Mateo; André A. S. F. Toledo; Maria das Graças Carvalho; Paulo Caramelli; Karina B. GomesJ. Bras. Patol. Med. Lab. 2015;51(6):376-382DOI: 10.5935/1676-2444.20150059 ABSTRACT INTRODUCTION: Several studies have been conducted in order to validate cerebrospinal fluid biomarkers for the diagnosis of Alzheimer’s disease (AD), aiming primarily to facilitate

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Underreporting of scientific knowledge: a theme for reflection

Cerebrospinal fluid biomarkers for the differential diagnosis of Alzheimer’s disease

Aplicação de biomarcadores do fluido cerebrospinal no diagnóstico diferencial da doença de Alzheimer Carolina A. Magalhães1; Micheli Figueiró1; Vanessa G. Fraga1; Elvis C. Mateo2; André A. S. F. Toledo1; Maria das Graças Carvalho1; Paulo Caramelli1; Karina B. Gomes1 1. Universidade Federal de Minas Gerais (UFMG)2. Instituto Hermes Pardini DOI: 10.5935/1676-2444.20150059 Corresponding author Karina Braga GomesFaculdade

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Quantification of cardiac and oxidative stress makers in different experimental groups A) total CK; B) CK-MB; C) TBARS. Data are expressed as mean ± SEM; * p < 0.05 when compared to group without MI. CK: creatine kinase; CK-MB: creatine-kinase MB fraction; TBARS: thiobarbituric acid reactive substances; SEM: standard error of the mean; MI: myocardial infarction.

Use of ischemia modified albumin for the diagnosis of myocardial infarction

Nariélle F. Bonorino; Adroaldo Lunardelli; Jarbas R. OliveiraJ. Bras. Patol. Med. Lab. 2015;51(6):383-388DOI: 10.5935/1676-2444.20150060 ABSTRACT INTRODUCTION: Literature reports addressing ischemia modified albumin (IMA) as a good marker for the early diagnosis of myocardial ischemia through albumin cobalt binding (ACB) test, that is before myocardial infarction (MI) occurs.OBJECTIVE: To evaluate the IMA plasmatic levels in infarcted patients, in

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