wadmin – Page 16 – Brazilian Journal of Pathology and Laboratory Medicine

Underreporting of scientific knowledge: a theme for reflection

Is muscle biopsy still necessary for the diagnosis of mitochondrial disease?

Paulo Victor S. Souza; Wladimir B. V. R. Pinto; Acary S. B. Oliveira Universidade Federal de São Paulo (Unifesp), São Paulo, Brazil Mitochondria are essential organelles for human life and play a central role in diverse cellular processes such as energy production, reactive oxygen species, biosynthetic intermediates, autophagy, amino acid and fatty acid synthesis and […]

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Is muscle biopsy still necessary for the diagnosis of mitochondrial disease?

Article Type, Editorial, Issue, Vol 54, Issue 5 / wadmin

Paulo Victor S. Souza; Wladimir B. V. R. Pinto; Acary S. B. OliveiraJ. Bras. Patol. Med. Lab. 2018;54(5):272DOI:10.5935/1676-2444.20180046 ABSTRACT Mitochondria are essential organelles for human life and play a central role in diverse cellular processes such as energy production, reactive oxygen species, biosynthetic intermediates, autophagy, amino acid and fatty acid synthesis and degradation, heme synthesis,

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Aspartate aminotransferase to platelet ratio index (APRI) for differentiation of primary and secondary infection by dengue virus

Original Article / wadmin

Aplicação do índice de relação aspartato aminotransferase sobre plaquetas (APRI) na diferenciação de infecção primária e secundária pelo vírus da dengue Suellen R. Martins, Melina B. Pinheiro, Luci Maria S. Dusse, Ana Paula L. Mota, Patrícia N. Alpoim 1. Universidade Federal de Minas Gerais (UFMG), Minas Gerais, Brazil2. Universidade Federal de São João del-Rei (UFSJ),

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Aspartate aminotransferase to platelet ratio index (APRI) for differentiation of primary and secondary infection by dengue virus

Article Type, Issue, Original Article, Vol 54, Issue 5 / wadmin

Suellen R. Martins, Melina B. Pinheiro, Luci Maria S. Dusse, Ana Paula L. Mota, Patrícia N. AlpoimJ. Bras. Patol. Med. Lab. 2018;54(5):273-278DOI:10.5935/1676-2444.20180047 RESUMO INTRODUÇÃO: A infecção pelo vírus da dengue (DENV) é considerada um grande problema de saúde pública nos países tropicais. A indisponibilidade de testes sorológicos em centros de saúde pública pode afetar negativamente o

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Evaluation of acute toxicity of β-lapachone associated with chitosan as a cytoprotective agent

Original Article / wadmin

Avaliação da toxicidade aguda da β-lapachona associada à quitosana como agente citoprotetor Maria Eduarda F. A. G. Oliveira1; Érika Cristina G. M. Silva2; Celso A. Câmara3; Ivone Antônia de Souza1; Rosa Valéria S. Amorim1 1. Universidade Federal de Pernambuco (UFPE), Pernambuco, Brazil2. Faculdade Maurício de Nassau, Pernambuco, Brazil3. Universidade Federal Rural de Pernambuco, Pernambuco, Brazil

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FTIR of β-LAP, DpCS and the β-LAP/DpCS conjugate

Evaluation of acute toxicity of β-lapachone associated with chitosan as a cytoprotective agent

Article Type, Issue, Original Article, Vol 54, Issue 5 / wadmin

Maria Eduarda F. A. G. Oliveira; Érika Cristina G. M. Silva; Celso A. Câmara; Ivone Antônia de Souza; Rosa Valéria S. AmorimJ. Bras. Patol. Med. Lab. 2018;54(5):279-287DOI:10.5935/1676-2444.20180048 RESUMO INTRODUÇÃO: A β-lapachona (β-LAP), um potente agente antitumoral, tem uso terapêutico limitado devido a sua baixa solubilidade e elevada toxicidade. Uma possível estratégia para contornar esses inconvenientes pode

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Molecular association of pathogenicity and resistance to multiple antimicrobials in Acinetobacter baumannii strains recovered from patients with diverse infectious diseases

Original Article / wadmin

Associação molecular de fatores de patogenicidade e resistência a múltiplos antimicrobianos em linhagens de Acinetobacter baumannii recuperados de pacientes com doenças infecciosas diversas Rafaela O. França1; Priscila S. Costa1; Guilherme Luiz Milanez1; Maria Rosa Q. Bomfim2; Ricardo Gonçalves1; Luiz M. Farias1; Vandack Nobre1; Simone G. Santos1 1. Universidade Federal de Minas Gerais (UFMG), Minas Gerais, Brazil2. Centro

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Perceptual map via the main components for the variables

Molecular association of pathogenicity and resistance to multiple antimicrobials in Acinetobacter baumannii strains recovered from patients with diverse infectious diseases

Article Type, Issue, Original Article, Vol 54, Issue 5 / wadmin

Rafaela O. França; Priscila S. Costa; Guilherme Luiz Milanez; Maria Rosa Q. Bomfim; Ricardo Gonçalves; Luiz M. Farias; Vandack Nobre; Simone G. SantosJ. Bras. Patol. Med. Lab. 2018;54(5):288-295DOI:10.5935/1676-2444.20180049 RESUMO INTRODUÇÃO: O sucesso das infecções por Acinetobacter baumannii pode ser atribuído a seus vários fatores de virulência e a mecanismos de resistência a antimicrobianos.OBJETIVO: Avaliar a presença e a correlação

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HER2-expressing breast tumors are associated with breast cancer stem-cell phenotype CD44+/CD24-

Article Type, Issue, Original Article, Vol 54, Issue 5 / wadmin

Tumores de mama que superexpressam HER2 estão associados ao fenótipo de células-tronco tumorais CD44+/CD24 Iris Rabinovich1,2; Lúcia de Noronha1; Ana Paula M. Sebastião2; Rubens S. Lima2; Cícero A. Urban3; Eduardo Schunemann Jr.2; Selene Elífio-Esposito1; Cleverton C. Spautz2; Andréa N. Moreno-Amaral1 1. Pontifícia Universidade Católica do Paraná (PUCPR), Paraná, Brazil2. Universidade Federal do Paraná (UFPR), Paraná,

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Table 3 − Distribution of the sample in relation to histological grade, tumor size, and lymph node

HER2-expressing breast tumors are associated with breast cancer stem-cell phenotype CD44+/CD24-

Original Article / wadmin

Iris Rabinovich; Lúcia de Noronha; Ana Paula M. Sebastião; Rubens S. Lima; Cícero A. Urban; Eduardo Schunemann Jr.; Selene Elífio-Esposito; Cleverton C. Spautz; Andréa N. Moreno-AmaralJ. Bras. Patol. Med. Lab. 2018;54(5):310-318DOI:10.5935/1676-2444.20180052 RESUMO INTRODUÇÃO: De acordo com a teoria das células-tronco tumorais, os tumores são originários de uma pequena população de células-tronco que perdem o mecanismo de

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