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Concentration of serum TG of subjects with and without hypercholesterolemia measured after 12-hour fast and during postprandial period Figure shows the serum TG concentration of male subjects without (n = 13) and with (n = 8) hypercholesterolemia (A), and of male subjects with hypercholesterolemia using (n = 5) or not (n = 3) oral drugs (B). It also shows the serum TG concentration of female volunteers without (n = 15) and with (n = 14) hypercholesterolemia (C), and female volunteers with hypercholesterolemia using (n = 8) or not (n = 6) oral medications (D). The data represent the mean ± standard error of mean. TG: triglyceride; *p < 0.05 and ***p < 0.001 when comparing fasting and postprandial values obtained from the same individual (paired samples t-test).

The influence of different types of fasting on lipid profile of volunteers from a city of Rio Grande do Sul, Brazil

Cláudia Regina Colla; Diego Carvalho; Aline P. RemorJ. Bras. Patol. Med. Lab. 2019;55(4):360-377DOI: 10.5935/1676-2444.20190033 ABSTRACT INTRODUCTION: Determination of lipid profile includes triglycerides (TG), total cholesterol and fractions as high-density lipoprotein cholesterol (HDL-c) and low-density lipoprotein cholesterol (LDL-c). These parameters are valuable in the risk assessment of developing cardiovascular disease. However, some pre-analytical factors, such as the […]

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Underreporting of scientific knowledge: a theme for reflection

The influence of different types of fasting on lipid profile of volunteers from a city of Rio Grande do Sul, Brazil

A influência de diferentes tipos de jejum no perfil lipídico em voluntários de um município do Rio Grande do Sul, Brasil Cláudia Regina Colla; Diego Carvalho; Aline P. Remor Universidade do Oeste de Santa Catarina (Unoesc), Joaçaba, Santa Catarina, Brazil Corresponding author Aline Pertile RemorORCID 000-0002-6881-6255e-mail: alineremor@gmail.com First Submission on 2/15/2019 Last Submission on 2/19/2019Accepted for publication on 3/11/2019Published

The influence of different types of fasting on lipid profile of volunteers from a city of Rio Grande do Sul, Brazil Read More »

Underreporting of scientific knowledge: a theme for reflection

Aquios CL flow cytometer performance in the automated quantification of lymphocyte subpopulations

Desempenho do citômetro de fluxo Aquios CL na quantificação automatizada de subpopulações linfocitárias Laiz C. Bento; Rodolfo P. Correia; Eduardo C. Pedro; Anderson M. Alexandre; Andressa C. Vaz; Daniela Schimidell; Rodrigo S. Barroso; Nydia S. Bacal Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil Corresponding author Laiz Cameirão BentoORCID 0000-0003-2258-4150e-mail: laiz.bento@einstein.br First Submission on 12/28/2018 Last

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Gating strategy used in the FC500 cytometer and Kaluza analysis software A) selection of the viable population by means of side scatter × forward scatter; B) side scatter × CD45 with gate in the region of total lymphocytes; C, D, E) inside the gate of lymphocytes, we identified populations of T, B, and NK lymphocytes; F, G, H) still inside the gate of lymphocytes, we identified a population of CD3 T lymphocytes and the CD4 and CD8 subpopulations.

Aquios CL flow cytometer performance in the automated quantification of lymphocyte subpopulations

Laiz C. Bento; Rodolfo P. Correia; Eduardo C. Pedro; Anderson M. Alexandre; Andressa C. Vaz; Daniela Schimidell; Rodrigo S. Barroso; Nydia S. BacalJ. Bras. Patol. Med. Lab. 2019;55(4):378-389DOI: 10.5935/1676-2444.20190034 ABSTRACT Flow cytometry (FC) is an essential tool for diagnosis, prognosis and therapeutic follow-up of several hematologic malignancies. In addition, it performs the quantification of lymphocytes

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Clinical and laboratory evolution of measles IgM and IgG: immunoglobulin class M and G. Source: Adapted from WHO, 2007.

Clinical, laboratorial diagnosis and prophylaxis of measles in Brazil

Analucia R. Xavier; Thalles S. Rodrigues; Lucas S. Santos; Gilmar S. Lacerda; Salim KanaanJ. Bras. Patol. Med. Lab. 2019;55(4):390-401DOI: 10.5935/1676-2444.20190035 ABSTRACT Measles is an acute febrile exanthematic disease of viral etiology, highly contagious, being the cause of morbidity and mortality of children in developing countries, whereas it has become rarer in developed countries due to

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Underreporting of scientific knowledge: a theme for reflection

Clinical, laboratorial diagnosis and prophylaxis of measles in Brazil

Analucia R. Xavier1; Thalles S. Rodrigues1; Lucas S. Santos1; Gilmar S. Lacerda1,2; Salim Kanaan1 1. Universidade Federal Fluminense (UFF), Niterói, Rio de Janeiro, Brazil2. Hospital Universitário Antônio Pedro, Niterói, Rio de Janeiro, Brazil Corresponding author Analucia Rampazzo XavierORCID 0000-0003-4501-1857e-mail: analuciaxavier@id.uff.br First Submission on 4/15/2019 Last Submission on 4/16/2019Accepted for publication on 4/16/2019Published on 8/20/2019 ABSTRACT Measles is an acute febrile

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Cadeia de rastreabilidade metrológica Adaptado de ISO 17511:2003(14).

Rastreabilidade em medicina laboratorial: um estímulo global para resultados exatos no cuidado com o paciente

Jane Luíza N. Fernandes; Wagner Wollinger; Bruno C. GarridoJ. Bras. Patol. Med. Lab. 2019;55(4):402-411DOI: 10.5935/1676-2444.20190036 ABSTRACT Laboratory medicine results influence a high percentage of all clinical decisions. Globalization requires that laboratory medicine results should be transferable between methods in the interests of patient safety. International collaboration is necessary to deliver this requirement. That collaboration should

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Underreporting of scientific knowledge: a theme for reflection

Rastreabilidade em medicina laboratorial: um estímulo global para resultados exatos no cuidado com o paciente

Jane Luíza N. Fernandes; Wagner Wollinger; Bruno C. Garrido Instituto Nacional de Metrologia, Qualidade e Tecnologia (Inmetro), Duque de Caxias, Rio de Janeiro, Brasil Corresponding author Bruno Carius GarridoORCID 0000-0001-5068-9879e-mail: garridobrunoc@gmail.com First Submission on 1/23/2019 Last Submission on 1/25/2019Accepted for publication on 4/3/2019Published on 8/20/2019 ABSTRACT Laboratory medicine results influence a high percentage of all clinical decisions. Globalization requires that

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Microscopy, 400×, HE: spindle cells, with elongated nuclei and abundant cytoplasm HE: hematoxylin and eosin.

Giant gastrointestinal stromal tumor of the proximal ileum

Kelen Christina A. BezzerraJ. Bras. Patol. Med. Lab. 2019;55(4):412-415DOI: 10.5935/1676-2444.20190037 ABSTRACT The gastrointestinal stromal tumors (GIST) are rare and consist in mesenchymal neoplasms of the gastrointestinal tract, which may affect any part of the gastrointestinal tract, and is more frequent in stomach. We report a case of a 65-years-old male patient who presented a mass

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Underreporting of scientific knowledge: a theme for reflection

Giant gastrointestinal stromal tumor of the proximal ileum

Tumor estromal gastrointestinal gigante do íleo proximal Kelen Christina A. Bezzerra Hospital São Francisco, Concórdia, Santa Catarina, Brazil Corresponding author Kelen Christina Alves BezzerraORCID 0000-0001-7914-432Xe-mail: drpatologia@hospitalsaofrancisco.com First Submission on 3/29/2019 Last Submission on 4/3/2019Accepted for publication on 4/3/2019Published on 8/20/2019 ABSTRACT The gastrointestinal stromal tumors (GIST) are rare and consist in mesenchymal neoplasms of the gastrointestinal tract, which may affect

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