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Morphological and immunohistochemical characteristics of the resected specimens A) urothelial papillary neoplasia, HE 20×; B) invasive urothelial carcinoma with discohesive growth pattern, HE 200×; C) tumor cells showed eosinophilic cytoplasm and visible nucleoli, often with intracytoplasmic vacuoles and peripheral nucleus, HE 400×; D) negative for E-cadherin staining, 200×. HE: hematoxylin and eosin.

Invasive bladder urothelial carcinoma, plasmacytoid variant: case report

Rui Pedro C. M. Oliveira; Carlos Filipe C. Abrantes; Edgar Miguel C. T. Silva; Carol A. Marinho; Vítor Manuel L. Sousa; Lígia R. C. O. A. P. CastroJ. Bras. Patol. Med. Lab. 2016;52(4):262-265DOI: 10.5935/1676-2444.20160043 ABSTRACT Invasive bladder urothelial carcinoma, plasmacytoid variant is a rare entity with scarce cases reported in the literature. We report a […]

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Underreporting of scientific knowledge: a theme for reflection

Invasive bladder urothelial carcinoma, plasmacytoid variant: case report

Carcinoma urotelial invasor de bexiga, variante plasmocitoide: relato de caso Rui Pedro C. M. Oliveira; Carlos Filipe C. Abrantes; Edgar Miguel C. T. Silva; Carol A. Marinho; Vítor Manuel L. Sousa; Lígia R. C. O. A. P. Castro Centro Hospitalar e Universitário de Coimbra (CHUC), Portugal DOI: 10.5935/1676-2444.20160043 Corresponding author Rui Pedro Caetano Moreira de

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Photomicrograph showing areas with mucinous differentiation in urethral adenocarcinoma (100×). In detail (right and below), neoplastic cells with signet-ring appearance (400×)

Adenocarcinoma of the female urethra: a case report

José de Carvalho Neto; Sydney C. Leão; Ricardo Fakhouri; Roberto Gurgel; Julia Maria G. Dias; Nivaldo F. VieiraJ. Bras. Patol. Med. Lab. 2016;52(4):266-269DOI: 10.5935/1676-2444.20160044 ABSTRACT The urethral adenocarcinoma is a rare malignant tumor that affects predominantly women. Its incidence is higher after the age of 50 in this group. The knowledge about this disease is

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Underreporting of scientific knowledge: a theme for reflection

Adenocarcinoma of the female urethra: a case report

Adenocarcinoma de uretra feminina: relato de caso José de Carvalho Neto1; Sydney C. Leão2; Ricardo Fakhouri1; Roberto Gurgel1; Julia Maria G. Dias1; Nivaldo F. Vieira1 1. Universidade Federal de Sergipe (UFS), Sergipe, Brazil2. Universidade Federal de São Paulo (Unifesp), São Paulo, Brazil DOI: 10.5935/1676-2444.20160044 Corresponding author Sydney Correia LeãoUniversidade Federal de São Paulo (Unifesp)Departamento de

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Platelet interference in automated reticulocyte counting

Thales Gouveia LimeiraJ. Bras. Patol. Med. Lab. 2016;52(3):136DOI: 10.5935/1676-2444.20160027 Retired professor from Universidade Federal do Espírito Santo (Ufes), Espírito Santo, Brazil; Faculdade Multivix, Espírito Santo, Brazil Medicine has gone through an admirable improvement due to the arsenal of resources offered by scientific advancement, what allows for prolongation of life and the enhancement of its quality.

Platelet interference in automated reticulocyte counting Read More »

Underreporting of scientific knowledge: a theme for reflection

Platelet interference in automated reticulocyte counting

Thales Gouveia Limeira Retired professor from Universidade Federal do Espírito Santo (Ufes), Espírito Santo, Brazil; Faculdade Multivix, Espírito Santo, Brazil Medicine has gone through an admirable improvement due to the arsenal of resources offered by scientific advancement, what allows for prolongation of life and the enhancement of its quality. Among these resources, laboratory tests stand

Platelet interference in automated reticulocyte counting Read More »

Performance of anti-AF antibodies to distinguish secondary Sjögren's syndrome in RA patients A) ROC of anti-AF IgA with area = 0.502 (95% CI = 0.38-0.62); p = 0.96; B) ROC of anti- AF IgG with area = 0.52 (95% IC = 0.4-0.64); p = 0.67. AF: alpha-fodrin; RA: rheumatoid arthritis; ROC: receiver operating characteristic; IgA: immunoglobulin class A; CI: confidence interval; IgG: immunoglobulin class G.

Anti-alpha-fodrin antibodies in patients with Sjögren’s syndrome secondary to rheumatoid arthritis

Renato Nisihara; Thelma L. Skare; Elisa Cenci; Denise Gabardo; Flavia Nass; Shirley R. R. UtiyamaJ. Bras. Patol. Med. Lab. 2016;52(3):137-141DOI: 0.5935/1676-2444.20160023 ABSTRACT INTRODUCTION: The Sjögren’s syndrome (SS) is an autoimmune disease characterized by lymphocytic infiltration. The currently most researched antibodies for its diagnosis are anti-La and anti-Ro, which, however, have low specificity in the case of

Anti-alpha-fodrin antibodies in patients with Sjögren’s syndrome secondary to rheumatoid arthritis Read More »

Underreporting of scientific knowledge: a theme for reflection

Anti-alpha-fodrin antibodies in patients with Sjögren’s syndrome secondary to rheumatoid arthritis

Anticorpos antialfafodrina em pacientes com síndrome de Sjögren’ secundária a artrite reumatoide Renato Nisihara1, 2; Thelma L. Skare1; Elisa Cenci1; Denise Gabardo1; Flavia Nass3; Shirley R. R. Utiyama3 1. Faculdade Evangélica do Paraná (Fepar), Paraná, Brazil2. Universidade Positivo (UP), Paraná, Brazil3. Universidade Federal do Paraná (UFPR), Paraná, Brazil DOI: 0.5935/1676-2444.20160023 Corresponding author Renato NisiharaRua João

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Strategy of analysis for reticulocyte count by FC/TO and CD61PE A) selection of the population of interest, R1, based on morphometric aspects for the construction of graph B (FL1 × anti-CD61PE/FL2); B) identification of the homogeneous population, R2, and possible interferents - R3 and R4; C) quantification of the percentage of positive cells in the upper right quadrant (stained with TO) present in the R2 region - graph drawn with the combination of gates in R1 and R2 regions. FC/TO: method of reticulocyte count by flow cytometry, using thiazole orange; SSC: side scatter; FSC: forward scatter.

Evaluation of the interference of platelets in reticulocyte counting by flow cytometry using thiazole orange

Karina Augusta Viana; Olindo A. Martins Filho; Luci Maria S. Dusse; Lis R. V. Antonelli; Danielle M. V. Avelar; Renato S. Avelar; Maria das Graças CarvalhoJ. Bras. Patol. Med. Lab. 2016;52(3):142-148DOI: 10.5935/1676-2444.20160025 ABSTRACT INTRODUCTION: The reticulocyte count by flow cytometry (FC) – an automated counting method – can present errors due to the presence of interfering

Evaluation of the interference of platelets in reticulocyte counting by flow cytometry using thiazole orange Read More »

Underreporting of scientific knowledge: a theme for reflection

Evaluation of the interference of platelets in reticulocyte counting by flow cytometry using thiazole orange

Avaliação da interferência de plaquetas na contagem de reticulócitos por citometria de fluxo, utilizando laranja de tiazol Karina Augusta Viana1; Olindo A. Martins Filho2; Luci Maria S. Dusse1; Lis R. V. Antonelli2; Danielle M. V. Avelar3; Renato S. Avelar3; Maria das Graças Carvalho1 1. Universidade Federal de Minas Gerais (UFMG), Minas Gerais, Brazil2. Centro de

Evaluation of the interference of platelets in reticulocyte counting by flow cytometry using thiazole orange Read More »