Brazilian Journal of Pathology and Laboratory Medicine

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Reações CISH para detecção de DNA. Fotomicrografia de reação CISH para DNA A) fígado; B) baço; C) pulmão; D) cérebro; ampliação 40×. É possível observar o precipitado marrom no núcleo celular resultante da reação enzimática do DAB com a peroxidase do complexo anticorpo ligado ao híbrido formado entre a sequência-alvo e a sonda nas reações com a sonda positiva (direita) em comparação com as reações com a sonda negativa (esquerda)

Validation of chromogenic in situ hybridization reactions for detection of DNA and RNA in formalin-fixed and paraffin-embedded tissues

Rachel L. Monteiro; Daniela S. Damaceno; Lidia M. Kimura; Cinthya S. Cirqueira; Juliana M. Guerra; Leonardo José T. AraújoJ. Bras. Pathol. Med. Lab. 2019;55(1):49-58doi.org/10.5935/1676-2444.20190008 ABSTRACT INTRODUCTION: Chromogenic in situ hybridization (CISH) is used alternatively to the traditional immunohistochemical methods for the diagnosis of infectious diseases in formalin-fixed paraffin-embedded samples, since it presents high sensitivity and specificity. This type […]

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Underreporting of scientific knowledge: a theme for reflection

Validation of chromogenic in situ hybridization reactions for detection of DNA and RNA in formalin-fixed and paraffin-embedded tissues

Validation of chromogenic in situ hybridization reactions for DNA and RNA detection in formalin-fixed paraffin-embedded tissue Raquel L. Monteiro; Daniela S. Damaceno; Lidia M. Kimura; Cinthya S. Cirqueira; Juliana M. Guerra; Leonardo José T. Araújo Instituto Adolfo Lutz (IAL), São Paulo, São Paulo, Brasil Endereço para correspondência Leonardo José Tadeu de Araújo0000-0002-5427-4053e-mail: biomedleonardo@gmail.com Primeira Submissão em 06/03/2018 Última Submissão

Validation of chromogenic in situ hybridization reactions for detection of DNA and RNA in formalin-fixed and paraffin-embedded tissues Read More »

Underreporting of scientific knowledge: a theme for reflection

Comparative analysis of the histopathological and epidemiological profile of ductal and lobular breast carcinomas diagnosed at the hospital de clínicas da universidade federal do paraná during the period 2008-2013

Análise comparativa do perfil histopatológico e epidemiológico dos carcinomas ductal e lobular da mama diagnosticados no Hospital de Clínicas da Universidade Federal do Paraná entre 2008 e 2013 Heloisa Z. Rocha; Graciele C. M. Manica; Lucia de Noronha; Edneia A. S. Ramos; Giseli Klassen Universidade Federal do Paraná (UFPR), Curitiba, Paraná, Brazil Corresponding author Giseli

Comparative analysis of the histopathological and epidemiological profile of ductal and lobular breast carcinomas diagnosed at the hospital de clínicas da universidade federal do paraná during the period 2008-2013 Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Comparative analysis of the histopathological and epidemiological profile of ductal and lobular breast carcinomas diagnosed at the hospital de clínicas da universidade federal do paraná during the period 2008-2013

Heloisa Z. Rocha; Graciele C. M. Manica; Lucia de Noronha; Edneia A. S. Ramos; Giseli KlassenJ. Bras. Patol. Med. Lab. 2019;55(1):59-7410.5935/1676-2444.20190009 ABSTRACT   INTRODUCTION: Breast cancer is the second leading cause of cancer death among women worldwide, and epidemiological studies may help understanding its mechanisms.OBJECTIVE: To carry out a survey of the number of breast cancer cases

Comparative analysis of the histopathological and epidemiological profile of ductal and lobular breast carcinomas diagnosed at the hospital de clínicas da universidade federal do paraná during the period 2008-2013 Read More »

Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Fetal death: obstetric, placental and fetal necroscopic factors

Óbito fetal: fatores obstétricos, placentários e necroscópicos fetais Laura M. Giraldi; Thiago Ricardo K. Corrêa; Fabiana Schuelter-Trevisol; Carlos Otávio Gonçalves Universidade do Sul de Santa Catarina, Tubarão, Santa Catarina, Brazil Corresponding author Laura Martins Giraldi0000-0002-8586-1437e-mail: lauramgiraldi@gmail.com First Submission on 9/15/2018Last Submission on 9/15/2018Accepted for publication on 12/5/2018Published on 2/20/2019 ABSTRACT INTRODUCTION: Fetal death is defined as the death of the product

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Fetal death: obstetric, placental and fetal necroscopic factors

Fetal death: obstetric, placental and fetal necroscopic factors

Laura M. Giraldi; Thiago Ricardo K. Corrêa; Fabiana Schuelter-Trevisol; Carlos Otávio GonçalvesJ. Bras. Patol. Med. Lab. 2019;55(1):85-98DOI: 10.5935/1676-2444.20190007 ABSTRACT INTRODUCTION: Fetal death is defined as the death of the product of conception, regardless of gestational age.OBJECTIVES: The objective of this study was to investigate the maternal (obstetrical and placental) risk factors and the necropsy findings associated with

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Glomus tumor in the abdominal wall

Tumor glômico de parede abdominal Kelen Chistina A. Bezzerra; Djulienne Marly K. Reis; Franciele Carla Prichoa Hospital São Francisco, Concórdia, Santa Catarina, Brazil Corresponding author Kelen Chistina Alves Bezzerra0000-0001-7914-432Xe-mail: ke_b@zipmail.com.br First Submission on 9/4/2018Last Submission on 9/4/2018Accepted for publication on 10/29/2018Published on 2/20/2019 ABSTRACT The glomus tumor is a rare benign soft tissue tumor. We report a case of a

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Histopathology, 100× HE: encapsulated lesion composed of small round cells HE: hematoxylin and eosin stain.

Glomus tumor in the abdominal wall

Kelen Chistina A. Bezzerra; Djulienne Marly K. Reis; Franciele Carla PrichoaJ. Bras. Patol. Med. Lab. 2019;55(1):99-102DOI: 10.5935/1676-2444.20190001 ABSTRACT The glomus tumor is a rare benign soft tissue tumor. We report a case of a 45-year-old male patient who presented with a painful mass in the abdominal wall. The patient underwent total tumor resection and the

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Underreporting of scientific knowledge: a theme for reflection

Solitary fibrous tumor of the kidney: a report of two cases

Tumor fibroso solitário do rim: relato de dois casos Rui Pedro Caetano M. Oliveira1,2; Edgar Miguel C. L. T. Silva1; Carol dos Anjos Marinho1; José Ignacio Lopez3; Lígia Romana O. A. P. Castro1 1. Centro Hospitalar e Universitário de Coimbra (CHUC), Portugal2. Universidade de Coimbra, Coimbra, Portugal3. Hospital Universitario Cruces, Biocruces Institute, Euskal Herriko Unibertsitatea

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A) peripheral right tumor on CT scan; B) gross examination revealed a brown and capsulated lesion; C) histologically it was composed of elongated cells, with little atypia, intercalated by collagen bundles; D) the tumor cells were positive for CD34 CT: computed tomography.

Solitary fibrous tumor of the kidney: a report of two cases

Rui Pedro Caetano M. Oliveira; Edgar Miguel C. L. T. Silva; Carol dos Anjos Marinho; José Ignacio Lopez; Lígia Romana O. A. P. CastroJ. Bras. Patol. Med. Lab. 2019;55(1):103-109DOI: 10.5935/1676-2444.20190003 ABSTRACT Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm, composed of monotonous spindle cells, intermingled with collagen fibers. Kidney location is sporadic, with few

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