Brazilian Journal of Pathology and Laboratory Medicine

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CRISP3 glycoprotein: a good biomarker for prostate cancer?

Issue, Original Article, Vol 57, Issue 1 /

Aparecida de Lourdes Carvalho; Sebastião A. Pinto; Wagner G. dos SantosJ. Bras. Patol. Med. Lab. 2021;57(1):1-7 ABSTRACT INTRODUCTION: Cysteine-rich secretory protein 3 (CRISP3) is expressed at low levels in normal human prostate but often overexpressed in prostate cancer (PCa). The relevance of this overexpression for the malignancy of PCa is still unclear. The prognostic value of […]

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Impact of urinary selective antibiogram in primary care

Issue, Original Article, Vol 57, Issue 1 /

Margarida Pereira; Gabriela Poças; Valquíria AlvesJ. Bras. Patol. Med. Lab. 2021;57(1):1-5 ABSTRACT INTRODUCTION: Selective reporting of antibiotic susceptibility test results (selective antibiogram), is increasingly recognized as one of the key strategies of antibiotic stewardship programs. The objective of this study is to determine the impact of selective susceptibility reporting on ciprofloxacin utilization and Escherichia coli susceptibility

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Bleach-concentrated direct sputum smear microscopy procedure for diagnosis of pulmonary tuberculosis in poverty areas

Issue, Original Article, Vol 57, Issue 1 /

José L. O. Magalhães; Ana Albertina Araújo; Leonardo O. Silva; Ilyana O. Coutinho; Juliana F. C. Lima; Nilma C. Leal; Alzira M. P. AlmeidaJ. Bras. Patol. Med. Lab. 2021;57(1):1-8 ABSTRACT INTRODUCTION: Pulmonary tuberculosis caused by Mycobacterium tuberculosis is a serious public health problem affecting millions of people worldwide. The development of easy and low-cost diagnostic methods

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HPV detection in oral mucosa samples in pediatric patients

Issue, Original Article, Vol 57, Issue 1 /

Aline R. Gama; Marcos Antonio B. Carvalho Jr.; Isabela J. Wastowski; Stela O. Rodrigues; Maria Fernanda B. Souza; Lais S. Botacin; Melissa A. G. Avelino; Lilian Carla CarneiroJ. Bras. Patol. Med. Lab. 2021;57(1):1-5 ABSTRACT INTRODUCTION: The human papillomavirus (HPV) detection favors treatments for patients with clinical manifestations and limits future consequences for those with asymptomatic infections.OBJECTIVES: Therefore,

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Umbilical cord constriction as a cause of intrauterine fetal death

Issue, Original Article, Vol 57, Issue 1 /

Victor Antônio Kuiava; Henrique M. Pasqual; Ana Luiza S. Garcia; Bianca L. Barbarioli; Fernanda M. Carlotto; Gabriel K. Costa; Laurenlisiê L. H. Brittes; Maiara Christine Macagnan; Nathália Dal Prá Zucco; Rubens RodriguezJ. Bras. Patol. Med. Lab. 2021;57(1):1-5 ABSTRACT The umbilical cord constriction (UCC) is an uncommon condition and an important etiology for stillborn fetuses. The

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Complications of idiopathic thrombocytopenic purpura in pregnancy: a review of literature

Issue, Review Article, Vol 57, Issue 1 /

Camila L. Silva; Allyne Cristina GrandoJ. Bras. Patol. Med. Lab. 2021;57(1):1-9 ABSTRACT INTRODUCTION: Idiopathic thrombocytopenic purpura (ITP) is an acquired immune disorder that causes a reduction in platelet count, called thrombocytopenia. ITP during pregnancy usually presents some complications that may impair the outcome of pregnancy.OBJECTIVE: This literature review aimed to identify the main complications of ITP in

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

The influence of tobacco and alcohol in oral cancer: literature review

Issue, Review Article, Vol 57, Issue 1 /

Rafaella B. Leite; Ana Carla O. Marinho; Beatriz L. Costa; Maria Beatriz V. Laranjeira; Kleyber D. T. Araújo; Anaícla F. M. CavalcantiJ. Bras. Patol. Med. Lab. 2021;57(1):1-5 ABSTRACT In Brazil, smoking and drinking are more common in male patients, less frequently affecting female patients. The most diagnosed type of lesion is squamous cell carcinoma. This

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Evaluation of galectin-3 levels in patients with type 2 diabetes mellitus and chronic kidney disease

Article Type, Issue, Original Article, Vol 57, Issue 1 /

Isabella D. P. Souza; Kathryna F. Rodrigues; Nathália T. Pietrani; Adriana A. Bosco; Karina B. Gomes; Michelle T. AlvesJ. Bras. Patol. Med. Lab. 2021;57(1):1-9 ABSTRACT INTRODUCTION: Type 2 diabetes mellitus (T2DM) is the most common manifestation of diabetes, accounting for about 90% of diagnosed cases. The causes of T2DM are not fully understood, but its pathogenesis

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Pie charts showing percentages of patients with CTCs detected by analyses of the expression of TWIST-1, MGA and the combination of expression of both genes CTCs: circulating tumor cells.

The combination of mammaglobin A and TWIST-1 increases detection of circulating tumor cells in breast cancer

Issue, Original Article, Vol 57, Issue 1 /

Georgina Gallucci; Estefanía Massa; Carlos C. Funes; Roberto Tozzini; Sergio Ghersevich J. Bras. Patol. Med. Lab. 2021;57(1):1-10 ABSTRACT OBJECTIVES: Breast cancer cells that are released into the bloodstream are called circulating tumor cells (CTCs). CTCs can express different genes, like TWIST-1 and mammaglobin A (MGA). The aims of this study were to analyze the expression of TWIST-1 and MGA in the blood

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Distribuição dos valores medianos de testosterona total com os participantes da coleta realizando ou não jejum de 8 horas

Evaluation of the influence of pre-analytical factors on total testosterone levels in healthy young men

Article Type, Issue, Original Article, Vol 57, Issue 1 /

Isabela L. Lima; Isabelly M. Neves; Izabela R. Costa; Matheus C. Caplum; Pedro C. B. Oliveira; Rômulo C. Vaz de Mello J. Bras. Patol. Med. Lab. 2021;57(1):1-6 DOI: 10.5935/1676-2444.20210016 Evaluation of the influence of pre-analytical factors on total testostero ABSTRACT INTRODUCTION: Testosterone is the main hormone that regulates male reproductive functions, directly participating in spermatogenesis and

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