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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

CRISPR-Cas9 system: an alternative therapy for lung cancer

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Sistema CRISPR-Cas9: uma alternativa terapêutica para neoplasia pulmonar Amanda S. R. Almeida; Cleide B. SouzaCentro Universitário Lusíada, Santos, São Paulo, Brazil.J Bras Patol Med Lab. 2021; 57: 1-8.DOI: 10.5935/1676-2444.20210051 Correspondence AuthorAmanda Souza Reis AlmeidaORCID: 000-0001-5171-7405e-mail: amandasouzareis@icloud.com First Submission on 02/10/21Last Submission on 02/11/21Accepted for publication on 05/20/21Published on 12/20/21 ABSTRACT Neoplasms are caused by mutations […]

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

CRISPR-Cas9 system: an alternative therapy for lung cancer

Article Type, Issue, Review Article, Vol 57, Issue 1 /

Sistema CRISPR-Cas9: uma alternativa terapêutica para neoplasia pulmonar Amanda S. R. Almeida; Cleide B. SouzaJ Bras Patol Med Lab. 2021; 57: 1-8.DOI: 10.5935/1676-2444.20210051 ABSTRACT Neoplasms are caused by mutations in deoxyribonucleic acid (DNA) characterized by debilitating treatments and difficult early diagnosis. In 2018, there were 27,200 deaths from lung cancer and 31,270 new cases of

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Eficácia dos novos biomarcadores da injúria renal aguda em pacientes críticos: uma revisão sistemática

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Effectiveness of novel biomarkers of acute kidney injury in critically ill patients:a systematic review Akeme Laissa N. Coutinho1; Djalma G. Xavier Filho1; Marcel Christian M. Tenório2; Matheus R. Lopes1; Adirlene P. O. Tenório1,21Universidade Federal do Vale do São Francisco (UNIVASF), Paulo Afonso, Bahia, Brazil.2Clínica de Doenças Renais do Vale do São Francisco (CLIRENAL), Paulo Afonso,

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Effectiveness of novel biomarkers of acute kidney injury in critically ill patients: a systematic review

Article Type, Issue, Original Article, Vol 57, Issue 1 /

Eficácia dos novos biomarcadores da injúria renal aguda em pacientes críticos:uma revisão sistemática Akeme Laissa N. Coutinho1; Djalma G. Xavier Filho1; Marcel Christian M. Tenório2; Matheus R. Lopes1; Adirlene P. O. Tenório1,2J Bras Patol Med Lab. 2021; 57: 1-10.DOI: 10.5935/1676-2444.20210059 ABSTRACT Introduction: Acute kidney injury (AKI) is defined as an abrupt decrease in the glomerular

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The importance of flow cytometry in the diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria

Article Type, Issue, Review Article, Vol 57, Issue 1 /

Lethicia R. Ehlert; Camila L. Silva; Allyne Cristina GrandoJ. Bras. Patol. Med. Lab. 2021;57(1):1-8 ABSTRACT INTRODUCTION: The paroxysmal nocturnal hemoglobinuria (PNH) is an acquired clonal disease of the hematopoietic stem cells, and it is clinically characterized by chronic intravascular hemolysis, bone marrow failure and hypercoagulability leading to thrombosis. It is a rare disorder of the hematopoietic

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Hereditary hemochromatosis associated with the development of liver cirrhosis

Issue, Review Article, Vol 57, Issue 1 /

Taylla S. Costa; Jaqueline M. Ferreira; Marina F. Couto; Regina S. NascimentoJ. Bras. Patol. Med. Lab. 2021;57(1):1-10 ABSTRACT Hereditary hemochromatosis (HH) is an autosomal recessive disease, most often associated with mutations in the HFE gene, which result in continuous absorption of iron, causing its overload. Liver tissue is the main site of iron deposition; thus, high levels

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Interference of medicines in laboratory exams

Article Type, Issue, Review Article, Vol 57, Issue 1 /

Raquel S. Silva; Caroline P. Domingueti; Marlon S. Tinoco; Júlio César Veloso; Mariana L. Pereira; André O. Baldoni; Danyelle R. A. RiosJ. Bras. Patol. Med. Lab. 2021;57(1):1-15 ABSTRACT OBJECTIVE: Conduct a survey on the interference of drugs in laboratory tests.METHODOLOGY: To identify the interference of each medication in laboratory tests, the Municipal List of Essential Medicines (Remume)

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Interference of medicines in laboratory exams

Article Type, Issue, Review Article, Vol 57, Issue 1 /

Raquel S. Silva; Caroline P. Domingueti; Marlon S. Tinoco; Júlio César Veloso; Mariana L. Pereira; André O. Baldoni; Danyelle R. A. RiosJ. Bras. Patol. Med. Lab. 2021;57(1):1-15 ABSTRACT OBJECTIVE: Conduct a survey on the interference of drugs in laboratory tests.METHODOLOGY: To identify the interference of each medication in laboratory tests, the Municipal List of Essential Medicines (Remume)

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Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

Timeline analysis of IgA and IgG levels in Covid-19 hospitalized patients according to the clinical outcome

Issue, Original Article, Vol 57, Issue 1 /

Thalia Medeiros; Fabiana R. Carvalho; Renan Faustino; Gabriel M. C. Guimarães; Lilian S. Alves; Any Caroline Oliveira; Elzinandes L. Azeredo; Jorge R. Almeida; Luzia Maria O. Pinto; Andrea Alice SilvaJ. Bras. Patol. Med. Lab. 2021;57(1): ABSTRACT INTRODUCTION: Studies suggest the association between antibody production and the severity of coronavirus disease 2019 (Covid-19). Objectives: To evaluate the

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Evaluation of urinalysis pre-analytical phase in a private laboratory of Maringá city, Paraná, Brazil

Issue, Original Article, Vol 57, Issue 1 /

Mariana M. Saramela; Talma R. L. FernandesJ. Bras. Patol. Med. Lab. 2021;57(1):1-6 ABSTRACT INTRODUCTION: Routine urinalysis is among the most requested exams in the clinical laboratory, assisting in the diagnosis of various diseases and treatment follow-up. In this case, the pre-analytical phase is extremely important because the quality of the sample directly influences the analysis and

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