Hawraa Yousif Abed
Basic Sciences Branch, College of Nursing, University of Kerbala, Kerbala, Iraq
Asaad Abbas Khalaf
Basic Sciences Branch, College of Nursing, University of Kerbala, Kerbala, Iraq
Fatimah Ali Kareem
Basic Sciences Branch, College of Nursing, University of Kerbala, Kerbala, Iraq
ABSTRACT
Triglycerides are regarded as a primary contributor to metabolic syndrome and are being investigated as potential biomarkers for dyslipidemia that increase the risk of insulin resistance (IR). This study aimed to evaluate the reliability of triglyceride levels in diagnosing dyslipidemia and their correlation with IR in patients with type 2 diabetes mellitus (T2DM). The findings demonstrated a positive correlation between triglycerides and IR, as well as with other clinical and biochemical parameters. Linear regression analysis revealed that the risk of developing IR increased with advancing age, higher body mass index, longer disease duration, elevated total cholesterol, triglycerides, low-density lipoprotein (LDL), very low-density lipoprotein (VLDL), and HbA1c levels. Multiple logistic regression further showed that the risk of T2DM was higher in elderly individuals (≥60 years), followed by those aged 50–59 years, obese patients compared to normal-weight individuals, and those with longer duration (≥16 years). Elevated total cholesterol (≥240 mg/dL), triglycerides (200–499 mg/dL), and LDL (160–189 mg/dL) also contributed to higher risk, whereas increased high-density lipoprotein (≥60 mg/dL) was protective. In conclusion, elevated triglyceride levels are strongly indicative of dyslipidemia, and their association with insulin resistance highlights their role in obesity-, diabetes-, and cardiovascular-related complications. Emphasizing triglyceride monitoring in clinical practice is essential for better risk stratification and preventive healthcare strategies.
Keywords: Dyslipidemia, Insulin Resistance, Lipid Profilel, Triglycerides, Type 2 Diabetes.
