Ali Abdul Hussein Handooz
Ass. Prof. Medical college at/Al-Qadyssia University
Doaa Faris Jabaz
Al qadesiyah college of medicine
Ali Fawzi Abdalsahib
Physician, University of Al-Qadisiya/ College of Medicine/ department of Internal Medicine, Iraq
ABSTRACT
Background: Diabetic foot ulcers (DFUs) are a major complication of diabetes mellitus, contributing to significant morbidity, prolonged hospitalizations, and lower limb amputations. Advances in wound management and regenerative therapies offer promising solutions for improving ulcer healing and infection control. Objective: This study aimed to evaluate the effectiveness of novel wound management strategies in treating diabetic foot ulcers (DFUs) at Al-Diwaniyah Teaching Hospital, with a focus on biological dressings, advanced wound debridement techniques, and infection control strategies. Methods: A total of 100 diabetic patients with chronic foot ulcers were included in the study and classified into two groups: Group A: Received conventional wound care (debridement, saline irrigation, and standard antibiotics). Group B: Treated with a combination of advanced wound dressings (collagen-based, silver-impregnated, or hydrogel dressings), platelet-rich plasma (PRP) therapy, and topical antimicrobial agents. Patients were monitored for healing progression, infection rates, and need for surgical intervention over a 12-week follow-up period. Results: Group B showed a significantly higher ulcer healing rate (p < 0.05) compared to Group A. Infection control was superior in Group B, with a lower incidence of bacterial colonization and reduced need for systemic antibiotics. Reduced hospitalization duration and lower amputation rates were observed in patients receiving advanced wound management therapies. Conclusion: The use of innovative wound healing approaches, such as PRP therapy, advanced dressings, and targeted infection control strategies, significantly improves DFU healing outcomes compared to conventional care. These findings highlight the importance of integrating new therapeutic protocols into diabetic foot ulcer management to reduce complications and enhance patient recovery. Further research is needed to optimize personalized treatment strategies for DFUs.
Keywords: Diabetic Ulcers, Diabetes Patients, Hydrogels Autolytic Debridement, Hydrotherapy, Negative-Pressure Treatment (NPWT).
