Ahmed Salim Atea Ahmed
Department of Biology, College of Education for Pure Sciences, Tikrit University, Iraq
Qasim Azeez Razooqi
Department of Biology, College of Education for Pure Sciences, Tikrit University, Iraq
ABSTRACT
A laboratory study was conducted to evaluate the negative effects of cadmium chloride and lead acetate on the offspring of male albino rats, at the Department of Life Sciences/Faculty of Pure Sciences Education/University of Tikrit during 2023. The experiment included dividing the males into six groups: the first was a control group, the second was injected with 5 mg/kg of cadmium chloride, the third was injected with 10 mg/kg of cadmium chloride, the fourth was injected with 75 mg/kg of lead acetate, the fifth was injected with 150 mg/kg of lead acetate, and the sixth was injected with 5 mg/kg of cadmium chloride and 75 mg/kg of lead acetate per body weight. The injection was applied for 30 days. Groups of females (5 animals per group) were mated with 2 of the males that were injected with pollutants. After mating healthy female albino rats with male albino rats injected with different concentrations of cadmium chloride and lead acetate, the results were as follows: The presence of an effect of cadmium chloride at a concentration of 60 mg/kg on the embryos, as half of the number of embryos were deformed. The deformity was shortening of the forelimbs, protrusion of the mouth, difference in the curvature of the back, small size of the embryo, and difference in the shape and size of the placenta. At a concentration of 120 mg/kg of cadmium chloride on the embryos, the number of embryos was eight embryos and all were abnormal. At a concentration of 600 mg/kg of lead acetate after five days, one of the females died. A concentration of 1200 mg/kg of lead acetate recorded deformities that included small size of the embryo, straight back, body crack, swollen placenta, and black color. The effect of a concentration of 60 mg/kg of cadmium chloride and 60 mg/kg of lead acetate was that the first female gave birth after 20 days and the second female gave birth after 22 days and an abortion occurred in the third female after 14 days. Upon dissection, it was found that the embryos were not equal in the horns of the uterus, the size of the fetus was small, and the placenta was large.
Keywords: Cadmium Chloride, Lead Acetate, Offspring.
